A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington’s disease and multiple cancers.
Tag: Human Genome
Breakthrough microscopy technique “supersizes” cells to reveal genetic activity
Breakthrough microscopy techniques are helping researchers visualize the ways our molecules interact with the human genome. Researchers at Yale School of Medicine used a series of expandable gels to pull apart a cell and expand it to 4000 times its…
Identifying the Underlying Causes of Ovarian Cancer
Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women’s tumors do not respond to therapy.
The Human Genome at Super Resolution
Five-year NIH grant funds new Center for Genome Imaging @ HarvardMed, three other institutions.
The future of personalized medicine is in unlocking the hidden mechanism that controls which genes are activated, researcher says
New research by McMaster University evolutionary biologist Rama Singh suggests there is a layer hidden in our cells that controls how genes interact, and how the many billions of possible combinations produce certain results.
Leading Scientist Working to Complete the Human Genome to Join UCSC Faculty
Leading scientist known for working to complete the human genome will join UCSC faculty; Karen Miga is a longtime Genomics Institute researcher, recently named “one to watch” by the journal Nature.
Are Heavy Metals Toxic? Scientists Find Surprising New Clues in Yeast
Scientists at Berkeley Lab and UC Berkeley have compiled the most complete library yet of lanthanide heavy metals and their potential toxicity – by exposing baker’s yeast to lanthanides. Their findings could help researchers uncover hidden pathways between lanthanide metals and disease.
Genetic Code Evolution and Darwin’s Evolution Theory Should Consider DNA an ‘Energy Code’
Darwin’s theory of evolution should be expanded to include consideration of a DNA stability “energy code” – so-called “molecular Darwinism” – to further account for the long-term survival of species’ characteristics on Earth, according to Rutgers scientists. The iconic genetic code can be viewed as an “energy code” that evolved by following the laws of thermodynamics (flow of energy), causing its evolution to culminate in a nearly singular code for all living species, according to the Rutgers co-authored study in the journal Quarterly Review of Biophysics.
FSU biologist uses genome database to investigate cancer cells
Florida State University Professor of Biological Science David Gilbert is using the latest information about the human genome as a guide to better understand cancer. Gilbert and his FSU colleagues were part of a team that compared different cancer cell types to a database of normal human cells using a new method he developed that can identify the cell type from which cancers derive.
UAH collaboration with HudsonAlpha expands knowledge of how our cells work
In an effort to better understand how our cells work, scientists have studied the function of 208 proteins responsible for orchestrating the regulation genes in the human genome. A paper appearing in the journal “Nature” describes the collaborative effort.
Campus 20th anniversary of posting the assembled genome to the Internet
UC Santa Cruz researchers played a crucial role in early planning of the human genome project, in assembling the genome sequence, developing tools for its visualization and ensuring it remained in the public domain. They continue to have a major role in the ongoing analysis of the human genome.
Pioneering research reveals certain human genes relate to gut bacteria
The role genetics and gut bacteria play in human health has long been a fruitful source of scientific enquiry, but new research marks a significant step forward in unraveling this complex relationship.