Therapeutic Potential of Bizarre ‘Jumbo’ Viruses Tapped for $10M HHMI Emerging Pathogens Project

UC San Diego and its collaborating partners have been awarded $10 million from the Howard Hughes Medical Institute to leverage the biomedical promise of viruses known as bacteriophages as new therapeutic agents in the fight against the rising crisis of antibiotic-resistant bacterial infections.

Hydrogel Injections Treat Antibiotic-Resistant Infections After Hip, Knee Replacements

In APL Bioengineering, researchers develop an injectable hydrogel that treats infections around prosthetics without the problems caused by current treatments. The black phosphorus-enhanced gel has a porous structure, excellent injectability, and rapid self-healing properties. Tests show it has good stability and low toxicity to tissue cells, and irradiating the gel with near infrared light causes it to release silver ions. This process was highly efficient at inhibiting S. aureus, common bacteria that cause disease in humans.