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UrduReducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer’s disease in a mouse model, according to a new study publishing March 7th in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China. The results illuminate one pathway for entrance of peripheral immune cells into the brain, and may provide a new target for treatment of Alzheimer’s disease.
Tag: Messenger Rna
Messenger RNA COVID-19 vaccines greatly reduce risk of asymptomatic COVID-19 infection, spread to others
Ten days after receiving a second dose of a messenger RNA, or mRNA, vaccine for COVID-19, patients without COVID-19 symptoms are far less likely to test positive and unknowingly spread COVID-19, compared to patients who have not been vaccinated for COVID-19. The Pfizer-BioNTech and Moderna messenger RNA vaccines for COVID-19 are authorized for emergency use in the U.S.
Profiling the COVID-19 Coronavirus
The Weizmann Institute of Science and the Israel Institute for Biological Research took a new approach to fighting COVID: tracing the contacts between the virus’s genetic material and the cells’ protein-producing machinery. This could lead to better diagnostics and new treatments, as well as help clarify why COVID is so skilled in the process of infection.
Experimental vaccine that boosts antigen production shows promise against COVID-19
A bioengineering technique to boost production of specific proteins could be the basis of an effective vaccine against the novel coronavirus that causes COVID-19, new research suggests.
Tiny engineered therapeutic delivery system safely solves genetic problems in mice
Researchers report in Science Advances that the lipid-based nanoparticles they have engineered, carrying two sets of protein-making instructions, showed in animal studies that they have the potential to function as therapies for two genetic disorders.