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UrduRepeatedly heading a soccer ball has been previously associated with negative long-term brain health for professional players. However, a new study found that a small number of repeated soccer headers equivalent to a throw-in did not cause immediate neurophysiological deficits for teens, suggesting that limited soccer heading exposure in youth sports may not result in irreversible harm if players are properly trained.
Tag: Pediatrics
New Computational Tool Identifies Novel Targets for Cancer Immunotherapy
Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets. The tool, called “Isoform peptides from RNA splicing for Immunotherapy target Screening” (IRIS), was described in a paper published today in the Proceedings of the National Academy of Sciences.
Pandemic stress reshapes the placentas of expectant moms
Elevated maternal stress during the COVID-19 pandemic changed the structure, texture and other qualities of the placenta in pregnant mothers – a critical connection between mothers and their unborn babies – according to new research from the Developing Brain Institute at Children’s National Hospital.
When rural hospitals stop delivering babies, fewer mothers receive adequate pre-natal care
A study of Iowa hospitals finds that when a rural county loses its last labor and delivery unit, fewer expectant mothers who live there get adequate pre-natal care, even though that care is still available.
Children’s Hospital of Philadelphia, Princeton Researchers Identify Novel Genetic Disorder
Researchers have discovered a novel genetic disorder associated with neurodevelopmental differences. The discovery identified the disorder in 21 families from all over the world.
UT Southwestern, Children’s Health to lead clinical trial on pediatric cancer patients
UT Southwestern Medical Center will lead a national multicenter clinical trial to test a treatment strategy for pediatric cancer patients that has shown promising results in adults. The trial will examine the effects of combining several chemotherapy agents with an immunotherapy drug in children with solid tumors that have recurred or shown no significant response after initial treatment.
Extreme poverty a key driver for relapse in kids with ALL
Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren’t as poor, according to a study published in today’s issue of Blood.
Scientists narrow down pool of potential height genes
When it comes to height, our fate is sealed along with our growth plates—cartilage near the ends of bones that hardens as a child develops. Research publishing April 14 in the journal Cell Genomics shows that cells in these plates determine the length and shape of our bones and can hint at our stature.
Researchers Find Earlier Intervention Leads to Greater Improvements in Young Children on the Autism Spectrum
Researchers have demonstrated that starting intervention coaching parents of autistic toddlers as early as 18 months leads to better gains in language, social communication, and daily living skills.
From tragedy, a new potential cancer treatment
Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors’ location. Chemotherapy has debilitating side effects. New treatment options are desperately needed.
Wireless pacemakers may be safe, effective for children with irregular heart rhythms
Wireless or leadless pacemakers, commonly implanted in adults, may be a safe and effective short-term option for children with slow heartbeats, according to new research published today in Circulation: Arrhythmia and Electrophysiology, a peer-reviewed journal of the American Heart Association.
UT Southwestern surgeon offers insight on elbow injuries among young baseball players
Spring marks the arrival of baseball, and with it the risk of elbow injuries among young players. Tears or ruptures of the ulnar collateral ligament (UCL) are the most common elbow injury among baseball players from youth leagues to the major leagues, especially pitchers. The most severe cases require reconstructive surgery, commonly known as Tommy John surgery.
UT Southwestern researchers create model to assess post-tonsillectomy bleed rates
Researchers led by a team at UT Southwestern Medical Center have created a statistical model to identify standards for typical, high, or low rates of bleeding after pediatric tonsillectomies. The findings, published in JAMA Otolaryngology-Head & Neck Surgery, could help doctors and hospitals improve outcomes for the third-most common pediatric surgery in the U.S.
Shh! Intensive care incubators resonate sounds and risk damage to premature babies’ hearing, scientists say
For vulnerable premature babies, an incubator in the neonatal intensive care unit (NICU) is a lifesaver, but the consequences can last a lifetime.
Saint Joseph’s University Expert Available to Comment on Adderall Shortage in U.S.
What: According to a recent Washington Post article, prescriptions for Adderall rose more than 30% over the past five years and accelerated during the pandemic. Now, there is a nationwide shortage of the drug. Nearly 40% of all prescriptions for stimulants, including…
CHOP Researchers Develop First-Of-Its-Kind Prediction Model for Newborn Seizures
Researchers have developed a prediction model that determines which newborn babies are likely to experience seizures in the Neonatal Intensive Care Unit (NICU). This model could be incorporated into routine care to help the clinical team decide which babies will need electroencephalograms (EEGs) and which babies can be safely managed in the Neonatal Care Unit without monitoring through EEGs. This would allow families and providers to care for babies without intrusive and unnecessary procedures.
CHOP Researchers Find Strong Adolescent-Parent Relationships Lead to Better Long-term Health Outcomes in Young Adults
Researchers have found that adolescents who report strong relationships with their parents have better long-term health outcomes. Study findings suggest that investments in improving parent–adolescent relationships could help improve general health, mental health and sexual, health while also reducing substance use in young adulthood.
Vitamin A may reduce pancreatitis risk during ALL treatment
Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.
Simmons Cancer Center investigators receive nearly $15 million in CPRIT funding
Ten scientists in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $15 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to advance research on a wide range of cancer issues.
Healthy gut bacteria can help fight cancer in other parts of the body, UTSW researchers find
Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs. The findings, published in Science Immunology, shed light on why antibiotics can weaken the effect of immunotherapies and could lead to new cancer treatments.
CHOP Researchers Find Rate of Fatal Opioid Poisonings Among Children More Than Doubled Over 13-Year Span
Researchers found opioids were responsible for more than half of all fatal poisonings in children ages 5 and younger, more than double the proportion of fatal poisonings caused by opioids in 2005. Additionally, over-the-counter drugs still contribute to fatal poisonings in this age group despite increased regulation. The findings, published today in the journal Pediatrics, underscore the need for improved intervention to prevent further fatal poisonings.
Splicing Deregulation Detected and Targeted in Type of Childhood Leukemia
UC San Diego researchers delve deep into the unknown cause of pediatric acute myeloid leukemia to identify a gene splicing dysregulation and potential target for treating the disease, which often becomes treatment-resistant.
Kids with Cerebral Palsy Have More Small Muscle Fibers, More Stem Cells in Contractured Muscles
Article title: Resident muscle stem myogenic characteristics in postnatal muscle growth impairments in children with cerebral palsy Authors: Ryan E. Kahn, Timothy Krater, Jill E. Larson, Marysol Encarnacion, Tasos Karakostas, Neeraj M. Patel, Vineeta T Swaroop, Sudarshan Dayanidhi From the…
How do parents decide if they should vaccinate their kids against SARS-CoV-2?
For parents, the decision to vaccinate their kids against SARS-CoV-2 is complex, influenced by scientific evidence, political and social pressures, and views about individual versus collective benefits of vaccination.
Paying Family Members for At-Home Medical Care of Their Children Found to Be a Viable Answer to Healthcare Worker Shortage
A recent study found that a Medicaid program in Colorado can help address the shortage of home healthcare workers for children with complex medical needs by offering family members certified nursing assistant (CNA) training and paying them for at-home medical care their child requires. Results show that children who received family-CNA care were not more likely to be hospitalized than children cared for by a non-family CNA. Children with family-CNA caregivers also experienced greater care continuity since turnover was not an issue as it tends to be with traditional home healthcare workers. Findings were published in the Journal of Pediatrics.
Nationwide Children’s Hospital Emphasizes Importance of Lifesaving AED & CPR Training for Schools and Communities
While sudden cardiac arrest is rare, it can happen to anyone at any time – including children, non-athletes and healthy individuals. Educating youth and adults to act swiftly and use an AED when they witness medical emergencies can help save lives. The AED is a portable electronic device that automatically diagnoses potentially life-threatening heart rhythms and delivers a shock only if necessary.
CHOP Study Finds Multidisciplinary Approach Best When Assisting Families with Limited English Proficiency
Pediatric patients with limited English proficiency (LEP) may face additional challenges when they present to an emergency room. However, researchers found that a multidisciplinary approach helped implement the services of interpreters earlier and significantly improved the identification of these patients to help them receive the care they need.
Young pregnant adolescents at increased risk of preeclampsia, C-section, UTSW study shows
Young adolescents face different challenges in pregnancy compared with their older teenage peers and adults that are sometimes exacerbated by high rates of obesity, a new study by UT Southwestern researchers suggests. The findings, published in the American Journal of Obstetrics & Gynecology MFM, could highlight at-risk populations for targeted prevention efforts.
Youth Suicide Rates Increased During COVID-19 Pandemic, Especially Among Particular Subgroups
In a study published today in Pediatrics, researchers in the Center for Suicide Prevention and Research at Nationwide Children’s Hospital found that in the United States, youth suicides increased during COVID-19, with significantly more suicides than expected among males, non-Hispanic American Indian/Alaskan Native youth, and non-Hispanic Black youth.
School dental program prevents 80 percent of cavities with one-time, non-invasive treatment
In a study of nearly 3,000 schoolchildren, silver diamine fluoride—a liquid that is brushed onto the surface of teeth to prevent cavities or keep them from worsening—was as effective against cavities as dental sealants, the standard of care.
UCI to launch pre-health program with support from state of California
Irvine, Calif., Feb. 9, 2023 — Increasing underrepresented students’ access to careers in medicine is the focus of a new interdisciplinary, pre-health professional development program at the University of California, Irvine. A five-year, $3.6 million grant from the California Department of Health Care Access and Information will support UC PRIME Pre-Health Pathways, a resource for undergraduates from underserved communities who are interested in pursuing careers in healthcare.
Screening teens for vaping history key to diagnosing lung disease during pandemic
The severity of a lung disease associated with e-cigarettes in teens decreased during the COVID-19 pandemic, but hospitalizations from the disease continued to mount, according to a study of more than three dozen patients by UT Southwestern researchers published in Pediatric Pulmonology.
Large Study Identifies Risk Factors in Children with Chronic Kidney Disease
In a new study led by Children’s Hospital of Philadelphia (CHOP) and Nemours Children’s Health, researchers have overcome the obstacle of scale by analyzing electronic health record data from PEDSnet, a national multicenter pediatric network, to identify a large cohort of children with CKD, evaluate CKD progression, and examine clinical risk factors for kidney function decline. The findings were published in the Clinical Journal of the American Society of Nephrology.
Save children from common cold with higher physical activity
Higher physical activity levels associated with reduced respiratory infection such as the common cold susceptibility in children.
Rest isn’t best: Getting kids back to school sooner after a concussion can mean a faster recovery
Contrary to popular belief, rest may not always be the best cure after a concussion, new study published in JAMA Network Open finds.
Santhanam Suresh Will Receive ASRA Pain Medicine’s Prestigious Gaston Labat Award
Santhanam Suresh, MD, MBA, FAAP, FASA, has been named the 2023 Gaston Labat Award recipient and will present the Gaston Labat lecture at the ASRA Pain Medicine 48th Annual Regional Anesthesiology and Acute Pain Medicine Meeting, April 22, 2023, in Hollywood, FL.
New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children
Although rare compared to adult liver cancers, hepatoblastoma is the most common pediatric liver malignancy, and its incidence is increasing.
New drug for effective treatment of childhood brain tumor
Researchers at the University of Colorado Anschutz Medical Campus have discovered a drug combination that may offer a better prognosis for children diagnosed with MYC amplified Medulloblastoma, an often deadly form of brain cancer.
New study finds relatively few hospital NICU’s screen for social determinants of health
Social determinants of health (SDH) are the conditions in which people are born, grow, work, live and age that contribute to health outcomes across the lifespan.
Happy, Healthy Holiday Tips — Johns Hopkins Children’s Center Experts Available to Discuss Staying Safe and Healthy this Holiday Season
Navigating RSV, COVID-19 and the Flu As more people travel and gather with family and friends this holiday season, cases of COVID-19, RSV and the flu are high and, in some areas, rising across the country. How can we keep…
CHOP Researchers Identify Potential Genetic Variants Linked to Increased Cancer Risk in Children with Birth Defects
Researchers have identified several genetic variants associated with increased risk of cancer in children with non-chromosomal birth defects, such as congenital heart disease and defects of the central nervous system. While the risk of developing cancer is not as high as children with chromosomal birth defects, it is significantly higher than children with no birth defects at all, and the findings may provide a basis for early detection in these understudied patients.
CHOP Researchers Discover Genetic Variant Associated with Earlier Onset Childhood Epilepsy
Researchers have discovered a specific genetic variant in SCN1A, the most common genetic epilepsy, that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies. The researchers also identified a potentially effective treatment strategy.
Brain Organoids Reveal in Detail the Harms of Prenatal Alcohol Exposure
UC San Diego researchers used human brain organoids to study the effects of prenatal alcohol exposure on neural development, revealing significant harms in molecular detail.
Children’s Primary Care Medical Group Joins UC San Diego Health Network
Children’s Primary Care Medical Group and UC San Diego Health have affiliated to better serve the health care needs of families with children in the San Diego region.
UTSW scientists identify brain circuit that triggers rare, blood sugar-dependent epilepsy
A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.
Researchers uncover cellular signature to detect pediatric sleep apnea
Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.
New Tool Predicts Risk of Hospital Readmission for Children Before Discharge
Readily available electronic health record (EHR) data can be used to reliably identify readmission risk for children of all ages while they are still in the hospital, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago published in the journal JAMA Network Open. The newly developed and validated tool will be key in efforts to reduce hospitalizations within 30 days of discharge, which also should help free up scarce pediatric hospital beds.
How parents can help their kids with asthma avoid serious attacks
UTSW pediatric pulmonologist highlights how to reduce risk of serious asthma attack
Hülya Bayır Named Chief of Critical Care and Hospital Medicine in Pediatrics at Columbia University Vagelos College of Physicians and Morgan Stanley Children’s Hospital
Bayır is internationally known for her transformative work in neuronal injury, oxidative lipidomics, and lipid-based biomarker discovery, which will lead the way to novel redox therapies to protect the brains of critically ill patients.
“The Ripple Effect” New Study Illustrates Vast Influence Children’s Mental Health Concerns have on Workforce Challenges in America
“The Ripple Effect” study from On Our Sleeves found that the mental health of their children remains a concern for the large majority of working parents, with almost half of all parents reporting that in the past year their child’s mental health has been somewhat or extremely disruptive to their ability to work on most days.