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UrduThe discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.
Tag: Protein Interactions
Blind dating in bacteria evolution
Proteins are the key players for virtually all molecular processes within the cell. To fulfil their diverse functions, they have to interact with other proteins. Such protein-protein interactions are mediated by highly complementary surfaces, which typically involve many amino acids that are positioned precisely to produce a tight, specific fit between two proteins. However, comparatively little is known about how such interactions are created during evolution.
The clever glue keeping the cell’s moving parts connected
Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue.
What the mechanical forces behind protein folding can tell us about metastatic cancer
Cells communicate with themselves and their cellular environment through mechanical bonds. This work advances understanding of the role of these forces on proteins as they interact to accomplish their biological functions, including the control of cancer.
AF2Complex: Researchers Leverage Deep Learning to Predict Physical Interactions of Protein Complexes
Proteins are the molecular machinery that makes life possible, and researchers have long been interested in a key trait of protein function: their three-dimensional structure. A new study by Georgia Tech and Oak Ridge National Laboratory details a computational tool able to predict the structure protein complexes – and lends new insights into the biomolecular mechanisms of their function.