Claudia Padilla, MD, at Baylor Scott & White Health, discusses Alzheimer’s and a new treatment. What You Need to Know: Alzheimer’s disease is a type of dementia. The most common sign is short-term memory loss. New medication targets the protein…
Tag: Amyloid
Researchers Identify the Role of an Alzheimer’s Disease Risk Gene in the Brain
Inflammatory response linked to amyloid plaque buildup
Whole blood exchange could offer disease-modifying therapy for Alzheimer’s disease, study finds
A novel, disease-modifying therapy for Alzheimer’s disease may involve the whole exchange of blood, which effectively decreased the formation of amyloid plaque in the brains of mice, according to a new study from UTHealth Houston.
Do Some Diabetes Drugs Reduce the Risk of Alzheimer’s?
MINNEAPOLIS – People taking certain drugs to lower blood sugar for type 2 diabetes had less amyloid in the brain, a biomarker of Alzheimer’s disease, when compared to both people with type 2 diabetes not taking the drugs and people without diabetes. The new study, published in the August 11, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology, also found people taking these drugs, called dipeptidyl peptidase-4 inhibitors, showed slower cognitive decline than people in the other two groups.
Alzheimer’s microbe hypothesis gets major NIH funding
After years of paltry funding, research on the possible role of microbes in the causation of Alzheimer’s disease will now get a major infusion of grants from the NIH’s National Institute on Aging
Drug-Induced Liver Injury, Translational microRNA Biomarkers, and More Featured in January 2021 Toxicological Sciences
in the January 2021 issue, Toxicological Sciences offers an engaging slate of research in toxicology, from endocrine toxicology and biomarkers to genetic and epigenetic toxicology and mixtures toxicology.
Building better vaccines for the elderly
Chemist Meredith Jackrel studies protein misfolding and how it leads to disease. She is collaborating engineers to develop amyloid-inspired vaccine technologies specifically tailored for seniors. The approach could be relevant to COVID-19 as the elderly are particularly susceptible to its severe complications.
UCI-led study finds modifiable risk factors could play a role in Alzheimer’s disease
Amyloid is a key feature of Alzheimer’s disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer’s disease, according to a new study published this week. Other, modifiable risk factors, such as the amount of fats in our blood and how efficiently our bodies generate energy could also play important roles.
New Target for Drug Intervention in Alzheimer’s Disease Identified
BIRMINGHAM, Ala. – Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer’s disease and other dementias. The researchers suggest that the enzyme, a serine/threonine…