Tag: Muscle Loss

Blood Flow-restricted Resistance Exercise Could Help Counteract Age-related Muscle Loss

sarah JonasResearch Results

Low-load blood flow-restricted resistance exercise helped counter age-related muscle decay “with a modest exercise volume and in a very time-efficient manner.” The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for May.

Selenoprotein P Could Become Therapeutic Target for Muscle Loss Caused by Inactivity

sarah JonasResearch Alert

Article title: Selenoprotein P deficiency protects against immobilization-induced muscle atrophy by suppressing atrophy-related E3 ubiquitin ligases Authors: Halimulati Abuduwaili, Kyoko Kamoshita, Kiyo-Aki Ishii, Kenta Takahashi, Tuerdiguli Abuduyimiti, Li Qifang, Yuki Isobe, Hisanori Goto, Yujiro Nakano, Yumie Takeshita, Hiroaki Takayama, Kenichi…

Study Explores Effects of Resistance Training in Older Adults at the Cellular Level

sarah JonasResearch Results

Aging and related diseases are associated with alterations in oxidative status and low-grade inflammation, as well as a decreased endoplasmic reticulum (ER) unfolded protein response (UPR). UPR is a functional mechanism by which cells attempt to protect themselves against ER stress. Researchers analyzed these proteins in peripheral blood mononuclear cells of elderly subjects and used computer simulation to predict the key proteins associated with these biomolecules underlying physiological adaptations to exercise. They collected blood samples about five to six days before and after the training period and analyzed various oxidative stress biomarkers in peripheral blood mononuclear cells. The study takes research one step further in helping to elucidate the benefits of exercise in this population.