Study Explores Effects of Resistance Training in Older Adults at the Cellular Level

Aging and related diseases are associated with alterations in oxidative status and low-grade inflammation, as well as a decreased endoplasmic reticulum (ER) unfolded protein response (UPR). UPR is a functional mechanism by which cells attempt to protect themselves against ER stress. Researchers analyzed these proteins in peripheral blood mononuclear cells of elderly subjects and used computer simulation to predict the key proteins associated with these biomolecules underlying physiological adaptations to exercise. They collected blood samples about five to six days before and after the training period and analyzed various oxidative stress biomarkers in peripheral blood mononuclear cells. The study takes research one step further in helping to elucidate the benefits of exercise in this population.

Is weakness the new smoking? Muscle strength tied to biological age, study shows

Muscle weakness marked by grip strength is associated with accelerated biological age, a new study suggests. Results were found using “age acceleration clocks” based on DNA methylation, a process that provides a molecular biomarker and estimator of the pace of aging. Researchers say this suggests potential to adopt use of grip strength as a way to screen individuals for future risk of functional decline, chronic disease and early mortality.

UNH Expert Stresses Importance of Exercise For Seniors During Pandemic

During the pandemic, many people have been getting less physical activity and becoming more sedentary, especially seniors who are homebound for safety reasons. Experts at the University of New Hampshire say it is more important than ever for older adults to find safe and accessible ways to remain physically active to help strengthen muscles, improve balance, enhance their immune system and reduce stress while being safe at home.

Strength Training Improves Muscle Strength, Neuromuscular Function in Parkinson’s Disease

Article title: Maximal strength training in patients with Parkinson’s disease: Impact on efferent neural drive, force generating capacity, and functional performance Authors: Jan Helgerud, Simon Nørskov Thomsen, Jan Hoff, Arild Strandbråten, Gunnar Leivseth, Runar Jakobsen Unhjem, Eivind Wang From the…