news, journals and articles from all over the world.
Nonfood, plant-based biofuels have potential as a green alternative to fossil fuels, but the enzymes required for production are too inefficient and costly to produce. However, new research is shining a light on enzymes from fungi that could make biofuels economically viable.
Researchers have developed a novel synthetic substance that has the potential to be a more effective and safer way of delivering drugs around the body.
A team of researchers from Chula Faculty of Science in cooperation with the Faculty of Medicine, Khon Kaen University has developed the “Jelly Nata Probiotics” jelly drink made from pineapple to benefit the mental wellbeing of the elderly, add value to pineapple while also solving the oversupply of pineapples.
Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.
“The distinction between the past, present and future is only a stubbornly persistent illusion,” Albert Einstein wrote. Now, researchers have used evolutionary “time travel” to study how an enzyme has evolved, with implications for future design. They will present their results at ACS Fall 2021.
A new Iowa State University study details the structure of a critical enzyme present in SARS-CoV-2, the coronavirus that causes COVID-19. This enzyme removes nucleoside antiviral medications from the virus’s RNA, rendering many treatments ineffective. Scientists could use data uncovered in the new study to find ways to inhibit the enzyme, possibly leading to more effective treatments.
An international research group, led by Jamey Marth, Ph.D., a professor at Sanford Burnham Prebys, has shown that the Neuraminidase 3 (Neu3) enzyme is responsible for the onset and progression of colitis—a chronic digestive disease caused by inflammation of the colon.
The University of Portsmouth is now a key member of a collaborative effort funded by the United States Department of Energy (DOE) and industry to tackle the growing global crisis of plastic waste.
The enzyme manganese superoxide dismutase helps maintain human health by keeping the amount of reactive oxygen molecules in cells under control. Using neutron scattering at ORNL, researchers obtained a complete atomic portrait of the enzyme, revealing key information about its catalytic mechanism.
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health.
Researchers from the Cancer Science Institute of Singapore at the National University of Singapore found that little-known genes called “onco-requisite factors” can enlist other genes to assist them in helping cancer cells proliferate. The gene produces an enzyme called aldehyde dehydrogenase that recruits other enzymes to supply cancer cells with energy for growth. As such, depriving cells of aldehyde dehydrogenase may be a possible way to treat cancer.
Scientists discovered that histones act as an enzyme that converts copper into a form that can be used by the cells. The finding refutes earlier theories that copper spontaneously converts in the body into a usable state.
As the COVID-19 pandemic continues to spread, many researchers are studying epidemiological models to predict its propagation. However, a mathematician and expert in complex systems decided to focus on finding targets within SARS-CoV-2 for new drugs to attack. In the journal Chaos, he discusses the dramatic increase in the sensitivity of the main protease of SARS-CoV-2 to small disturbances, which made him suspect there is a role for inhibitors to play in killing the virus.
Article title: Helicobacter pylori infection impairs chaperone-assisted maturation of Na,K-ATPase in gastric epithelium Authors: Elizabeth A. Marcus, Elmira Tokhtaeva, Jossue L. Jimenez, Yi Wen, Bita V. Naini, Ashley N. Heard, Samuel Kim, Joseph Capri, Whitaker Cohn, Julian P. Whitelegge, Olga Vagin…
Researchers identified the mechanisms underlying the innate immune function of the enzyme caspase-6, offering ways to combat viral infection, inflammatory diseases and cancer.
Chemists and biochemists at UC San Diego took the first look at the onset of DNA-editing activity in an RNA-editing enzyme called “TadA” that served as the precursor to a class of base editors known as ABEs.
Canadian chemists discover a natural process to control the shape of “macrocycles,” molecules of large rings of atoms, for use in pharmaceuticals and electronics.
Researchers from Arts & Sciences have solved the X-ray crystal structure of the enzyme that makes obafluorin — a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria. This new class of antibiotics might provide a powerful antidote to the growing scourge of antibiotic resistance.
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