Suggests a more proactive, innate immune response among females
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include new targets involved in protecting DNA replication forks and preventing inflammatory responses, a new treatment option for elderly patients with late-stage acute myeloid leukemia, insights into the breast cancer tumor microenvironment, biomarkers of response to targeted and immune therapies, a novel cellular therapy option for osteosarcoma and a new target for inducing ferroptosis in cancer cells.
Researchers report the biological effects of influenza protein NS1 binding to RIG-I — the binding directly quiets the alarm that activates the cellular innate immunity defense against the infection. This is a newly described way for flu to antagonize the host cellular antiviral response.