Newly Identified Pathway, Biomarkers May Be Tools to Prevent Kidney Injury-induced Lung Damage

Article title: Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury

Authors: Mark Hepokoski, Jing Wang, Kefeng Li, Ying Li, Purva Gupta, Tina Mai, Alex Moshensky, Mona Alotaibi, Laura E. Crotty Alexander, Atul Malhotra, Prabhleen Singh

From the authors: “These findings provide a rationale for bench and translational studies using therapies that are already available, such as inhaled DNase or mitochondrial transplantation, to prevent lung injury and improve mortality due to [acute kidney injury].” 

This study is highlighted as one of April’s “best of the best” as part of the American Physiological Society’s APSselect program.

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