Controlling Cholesterol in Microglia Alleviates Chronic Pain, Opioid-Free

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment. Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used a mouse model to demonstrate the pivotal role of cholesterol in CIPN, and proposed a novel therapeutic approach to reverse it.

Understanding ‘Chemo Brain’ in Children: Researchers Secure $4.6 Million NIH Grant to Identify Those at Risk

Chemotherapy usually cures children diagnosed with acute lymphoblastic leukemia (ALL), but the treatment may hamper brain development and impact key cognitive functions including sensory processing, memory, and attention. Researchers at Albert Einstein College of Medicine, Children’s Hospital at Montefiore (CHAM), and Rutgers Cancer Institute of New Jersey have received a five-year, $4.6 million grant from the National Institutes of Health (NIH) to determine how chemotherapy exerts its damaging effects on the brain. Their long-term objective is to use this information to develop protective interventions that can prevent permanent harm.

Cardioprotective Drug Prevents Severe Cardiac Events in Children Undergoing Chemotherapy for Acute Myeloid Leukemia

The cardioprotective drug dexrazoxane preserved cardiac function in pediatric patients undergoing chemotherapy for acute myeloid leukemia (AML) without compromising overall patient survival and potentially improving it, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP). The results suggest dexrazoxane should be considered for cardioprotection in all pediatric patients undergoing standard chemotherapy for AML.

Baylor University Interior Design Team Helps Prepare a Hyperclean Play Space for Children with Compromised Immunity

A Baylor University interior design team is assisting Decon7 Systems — manufacturer of a powerful disinfectant used by the military, first responders and, most recently, hospitals in China as they battle Coronavirus Disease (COVID-19) 19 — in designing a hyperclean play space for children with diseases that compromise their immunity.

Exercise during Chemo, Activity Breaks Enhance Mood, Reducing Diabetes Risk in African American Men & More from Medicine & Science in Sports & Science

If you’re looking for health and fitness story ideas, view these research highlights from Exercise and Sport Sciences Reviews and Medicine & Science in Sports & Exercise®, ACSM’s flagship research journal.