An international team of researchers has used nanoparticles to deliver a drug—one that previously failed in clinical trials for pain—into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats. The findings are published Nov. 4 in Nature Nanotechnology.
Tag: Opioid
Opioid-Related Gifts from Pharma Companies Linked to Physician Prescribing by Specialty
Physicians who received gifts from pharmaceutical companies related to opioid medications were more likely to prescribe opioids to their patients in the following year, according to a new analysis.
Of All Professions, Construction Workers Most Likely to Use Opioids and Cocaine
Construction workers are more likely to use drugs than workers in other professions, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU College of Global Public Health.
Sanford Burnham Prebys awarded $3.58 million NIH grant to advance potential treatment for opioid-use disorders
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.
Designing a new class of drugs to treat chronic pain
A UC Davis research team, led by Vladimir Yarov-Yarovoy and Heike Wulff, will receive a $1.5 million grant from the National Institutes of Health (NIH) to develop a novel class of peptides that are better at treating pain and don’t have the side effects of opioids. The grant is part of the NIH initiative Helping to End Addiction Long-Term (HEAL Initiative).
Nearly 1 in 3 Patients with Lupus Use Prescription Opioids for Pain
A new study finds nearly one in three adults with lupus use prescription opioids to manage pain, despite a lack of evidence that opioids are effective for reducing pain from rheumatic diseases.
In the Near Future, Synthetic Opioids will have a Tougher Time Sneaking into the U.S. via International Mail or Express Carriers
CBP recently joined forces with DHS S&T for a project called Synthetic Opioid Detection at Speed (SODAS).
Other treatments can reduce need for addictive pain medication
Hardly a day goes by without the public being warned about the dangers of opioids. But still, according to the National Institute on Drug Abuse, more than 130 people die every day of opioid overdose and the problem is getting worse. A Houston Methodist pain specialist says new advancements in pain management are giving patients options.
Bankruptcy filing by Purdue Pharma not likely to protect Sackler Family
On Sunday, Purdue Pharma, the company that made billions from the sale of OxyContin, filed for bankruptcy days after reaching a tentative settlement with many of the state and local governments suing it over the toll of opioids. Indiana University…
Patients in the U.S. and Canada are Seven Times as Likely as those in Sweden to Receive Opioids After Surgery
Patients in the United States and Canada are seven times as likely as those in Sweden to receive a prescription for opioid medications after surgery, according to a new multi-institutional study led by researchers from Penn Medicine.
Aftermath of J&J ruling: Opioid expert available for comment
On Monday, an Oklahoma judge ruled Johnson & Johnson must more than half a billion dollars for its role in the state’s opioid crisis. Stefan Kertesz, M.D., an addiction scholar and professor at the University of Alabama at Birmingham School…
New Data Indicate Rise in Opioid Use for Migraine Treatment
An increasing number of Americans are using opioids to treat their migraine headaches, despite the fact that opioids are not the recommended first-line therapy for migraine in most cases. Migraine care specialist Sait Ashina, MD, a neurologist and Director of the Comprehensive Headache Center at the Arnold-Warfield Pain Center at Beth Israel Deaconess Medical Center, presented the survey findings at the 61st annual meeting of the American Headache Society.
Factors Orthopaedic Surgeons Should Consider When Prescribing Opioids
Orthopaedic surgeons are the third-highest physician prescribers of opioids, writing more than 6 million prescriptions a year. Because over-dispensing of opioids is a factor contributing to the ongoing opioid epidemic, researchers at Johns Hopkins surveyed orthopaedic providers to better understand…