A multicenter, longitudinal study, co-led by investigators at the Vanderbilt Diabetes Research and Training Center (DRTC), has discovered that a small pancreas size predicts a faster progression to stage 3 Type 1 diabetes (T1D), the point at which clinical diagnosis occurs.
Tag: Autoantibodies
Proteins Predict Significant Step Toward Development of Diabetes
Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.
Novel autoantibody adds fuel to COVID-19 “firestorm” of inflammation, blood clots
Researchers at Michigan Medicine have discovered another functional autoantibody in COVID-19 patients that contributes to the disease’s development and the “firestorm” of blood clots and inflammation it induces. The autoantibody makes it harder for the body to degrade neutrophil extracellular traps, the toxic webs of DNA and proteins produced by overactive immune cells at heightened levels in COVID patients.
New Cause of COVID-19 Blood Clots Identified
A new study reveals that COVID-19 triggers production of antibodies circulating through the blood, causing clots in people hospitalized with the disease.
Some Severe COVID-19 Cases Linked to Genetic Mutations or Antibodies that Attack the Body
Two new studies offer an explanation for why COVID-19 cases can be so variable. A subset of patients has mutations in key immunity genes; other patients have auto-antibodies that target the same components of the immune system. Both circumstances could contribute to severe forms of the disease.