A research team has created CAR T cells that target an alternative B cell-specific surface marker, allowing them to effectively kill blood cancer cells that lack the prototypical target for CAR T therapy, CD19. The new T cells could help…
Tag: TOXICOLOGY
Study estimates more than 100,000 cancer cases could stem from contaminants in tap water
WASHINGTON – A toxic cocktail of chemical pollutants in U.S. drinking water could result in more than 100,000 cancer cases, according to a peer-reviewed study from Environmental Working Group – the first study to conduct a cumulative assessment of cancer…
A promising HIV vaccine shows signs of cross-protective benefits
One of the most successful candidate HIV vaccines to date – initially tested in Thailand, where it had modest effects – showed surprisingly strong efficacy when evaluated in a South African cohort, where a different strain of HIV is known…
Complexity of plastics make it impossible to know which are dangerous
Secret formulations and complex chemical cocktails make assessing safety a challenge
Controversial insecticides shown to threaten survival of wild birds
New research at the University of Saskatchewan (USask) shows how the world’s most widely used insecticides could be partly responsible for a dramatic decline in songbird populations. A study published in the journal Science on Sept. 13 is the first…
Some cancer drugs in clinical trials don’t work by hitting their targets
Multiple cancer drug candidates in clinical trials kill tumor cells through off-target effects instead of by interacting with their intended molecular targets, according to a new study. The unexpected findings demonstrate that the targets of these drugs are not essential…
IIVS receives support for non-animal testing from RIFM
September 10, 2019, Gaithersburg, MD – The Institute for In Vitro Sciences, Inc. (IIVS) is excited to announce that it has received a grant from the Research Institute for Fragrance Materials (RIFM) to support its mission to promote non-animal methods.…
UTEP School of Pharmacy awarded NIH grant to study thirdhand smoke
Researchers at The University of Texas at El Paso’s School of Pharmacy have been awarded $1.8 million from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to study the effects of thirdhand smoke…
E-cigarettes disrupt lung function and raise risk of infection
A study led by researchers at Baylor College of Medicine raises health concerns about the use of electronic cigarettes. Published in the Journal of Clinical Investigation , the work shows that chronic exposure to e-cigarette vapors disrupts normal lung function…
A new drug could revolutionize the treatment of neurological disorders
The international team of scientists from Gero Discovery LLC, the Institute of Biomedical Research of Salamanca, and Nanosyn, Inc. has found a potential drug that may prevent neuronal death through glucose metabolism modification in stressed neurons. The positive results obtained…
Biological risk potential of nanoparticles studied
Publication in Scientific Reports
How to practice safer sunscreening
Toxicity screening of cosmetics, sunscreens and pharmaceuticals is made easier with microfluidic dev
University Hospitals awarded $1 million from Ohio Opioid Technology Challenge
UH Care Continues technology kept more than 12,000 opioid pills out of circulation in just six month
Prenatal pesticide exposure linked to changes in teen’s brain activity
New study is one of the first to use advanced brain imaging to reveal how exposure to these chemical
University Hospitals awarded $1 million from Ohio Opioid Technology Challenge
UH Care Continues technology kept more than 12,000 opioid pills out of circulation in just six month
Prenatal pesticide exposure linked to changes in teen’s brain activity
New study is one of the first to use advanced brain imaging to reveal how exposure to these chemical
Metal particles abraded from tattooing needles travel inside the body
Allergic reactions are common side effects of tattoos and pigments have been blamed for this. Now researchers prove, for the first time, that particles wear from the needle during the tattooing process and contain the allergens nickel and chromium and…
Wild ground-nesting bees might be exposed to lethal levels of neonics in soil
In a first-ever study investigating the risk of neonicotinoid insecticides to ground-nesting bees, University of Guelph researchers have discovered at least one species is being exposed to lethal levels of the chemicals in the soil. Examining the presence of these…
Scientists use a new method to track pollution from cooking
Cooking organic aerosol (COA) is one of the most important primary sources of pollution in urban environments. There is growing evidence that exposure to cooking oil fumes is linked to lung cancer. Currently, the most effective method to identify and…
E-cigs can trigger same lung changes seen in smokers, emphysema
In a new UNC School of Medicine study led by Rob Tarran, PhD, biomedical researchers show how high l
Solving the big problem of measuring tiny nanoparticles
Tiny nanoparticles play a gargantuan role in modern life, even if most consumers are unaware of their presence. They provide essential ingredients in sunscreen lotions, prevent athlete’s foot fungus in socks, and fight microbes on bandages. They enhance the colors…