Mutational Signatures | sciencenewsnet.in

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Mutational signature linking bladder cancer and tobacco smoking found with new AI tool

September 26, 2022 sarah JonasResearch Results

UC San Diego researchers have for the first time discovered a pattern of DNA mutations that links bladder cancer to tobacco smoking. The work could help researchers identify what environmental factors, such as exposure to tobacco smoke and UV radiation, cause cancer in certain patients. It could also lead to more customized treatments for a patient’s specific cancer.

Researchers Develop New Method for Identifying Mutational Signatures in Cancer

March 30, 2021 sarah JonasResearch Results

Researchers at the Johns Hopkins Kimmel Cancer Center used machine learning techniques to detect mutational signatures in cancer patients. Their algorithm outperformed the current standard of analysis and revealed new mutational signatures associated with obesity, which is believed by cancer prevention experts to be becoming the most significant lifestyle factor contributing to cancer in the U.S. and most of the Western world.