A forte resposta imunológica relacionada com a covid -19 contribui para lesões renais

Os pesquisadores da Mayo Clinic descobriram que a lesão renal aguda associada com a COVID-19 é muito similar à lesão renal causada por sepse e que a resposta imunológica ativada pela doença exerce um papel central.

Detrás de la insuficiencia renal aguda relacionada con la COVID-19, hay una fuerte reacción inmunitaria

Los investigadores de Mayo Clinic descubrieron que la insuficiencia renal aguda relacionada con la COVID-19 actúa de forma similar al daño renal causado por la sepsis y que la reacción inmunitaria producida por la infección tiene un papel fundamental.

Strong immune response underlies acute kidney injury related to COVID-19

Mayo Clinic researchers have found that acute kidney injury associated with COVID-19 resembles sepsis-caused kidney injury, and the immune response triggered by the infection plays a pivotal role.

The findings, published in Mayo Clinic Proceedings, also suggest that mitochondrial dysfunction — a loss of function in cellular energy production — is commonly found in kidney injury related to COVID-19.

American Physiological Society (APS)

Low Dose of Bacterial Toxin Could Be Protective for Men at Risk of Acute Kidney Injury

Lipopolysaccharide improved outcomes for male, but not female, rats Charlottesville, Va. (June 25, 2019)—In a counterintuitive result, researchers found that giving male rats a low dose of the endotoxin lipopolysaccharide (LPS) prior to inducing a model of acute kidney injury…