The finding could help prevent deaths linked to sepsis and acute lung disease
Tag: Cell Biology
Novel paradigm in drug development
Understanding resistance mechanisms to targeted protein degradation
K+ Channel Study Could Help Develop Drugs for Life-Threatening Conditions
TTUHSC’s Cuello has Research Published in PNAS
A novel technology for genome-editing a broad range of mutations in live organisms
Salk scientists develop a new gene-editing tool that could help treat many disorders caused by gene
Evolution designed by parasites
While analyzing interactions between parasites and hosts, a substantial amount of research has been devoted to studying the methods parasitic organisms use to control host behavior. In “Invisible Designers: Brain Evolution Through the Lens of Parasite Manipulation,” published in the…
Computer model could help test new sickle cell drugs
PROVIDENCE, R.I. [Brown University] — A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease. The model, described in a paper published in Science Advances…
E-cigs can trigger same lung changes seen in smokers, emphysema
In a new UNC School of Medicine study led by Rob Tarran, PhD, biomedical researchers show how high l
UC San Diego Researchers Convert Pro-Tumor Macrophages into Cancer Killers
University of California San Diego School of Medicine researchers identified a new therapeutic approach in mouse models that halts drug resistance and cancer progression by using an antibody that induces the immune system via macrophages to seek and kill cancer cells.
Genetic redundancy aids competition among bacteria in symbiosis with squid
The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments. Some strains of luminescent bacteria that compete to colonize the…
TGen team links gene to children with physical and intellectual disabilities
DDX6 among a growing list of genes identified by TGen’s Center for Rare Childhood Disorders
WPI biologist’s discovery gives evolution clues and may affect drug interaction research
Worcester, Mass. – August 15, 2019 – A biologist at Worcester Polytechnic Institute (WPI) has shown that a key biological component in a worm’s communication system can be repurposed to take on a different job, a critical finding about the…
Immune cells drive gallstone formation
Sticky meshworks of DNA and proteins extruded by white blood cells called neutrophils act as the glue that binds together calcium and cholesterol crystals during gallstone formation, researchers in Germany report August 15 in the journal Immunity . Both genetic…
Pores for thought: Ion channel study beckons first whole-brain simulation
Blue Brain Project’s ‘Channelpedia’ is open to brain modellers and pharmacologists everywhere
Dartmouth receives $12.5 million grant to establish Center for Quantitative Biology
Dartmouth’s Geisel School of Medicine has been awarded a 5-year, $12.5 million grant from the National Institutes of Health (NIH) to establish a Center for Quantitative Biology (CQB) that will bring together and enhance initiatives in computational biology, bioinformatics, and…
Finnish discovery brings new insight on the functioning of the eye and retinal diseases
Finnish researchers have found cellular components in the epithelial tissue of the eye, which have previously been thought to only be present in electrically active tissues, such as those in nerves and the heart. A study at Tampere University found…
New drug targets early instigator of Alzheimer’s disease
Over a hundred years after they were first identified, two ominous signposts of Alzheimer’s disease (AD) remain central topics of research–both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies into senile plaques, which congregate in the…
Simple protocol for assessing maturation of HPCs from induced pluripotent stem cells
New Rochelle, NY, August 13, 2019-Researchers have developed a guide to help labs standardize the production of mature hepatic-like cells (HPCs) from stem cells and easily compare gene expression of HPCs to actual human liver tissue. This moderately high throughput…
Cambridge scientists reverse aging process in rat brain stem cells
New research, published today in Nature , reveals how increasing brain stiffness as we age causes brain stem cell dysfunction, and demonstrates new ways to reverse older stem cells to a younger, healthier state. The results have far reaching implications…
Sticky proteins help plants know when — and where — to grow
New research uncovers a mechanism that keeps hormone auxin in its place
Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes
The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.
Using 3D-Printing to Stop Hair Loss
In a new study, aimed at using stem cells for hair growth, Columbia researchers have created a way to grow human hair in a dish, which could open up hair restoration surgery to more people, including women, and improve the…
No cell is an island – ‘doublet’ immune cells
LJI team finds that ‘doublet’ immune cells are much more common—and more important in disease—than previously thought. LA JOLLA, CA – Sorting through individual immune cells is a handy way to see how the body responds to disease. For years,…
Frozen sperm retains its viability in outer space conditions
Human sperm samples exposed to microgravity are just as active and concentrated as on Earth Vienna, 24 June 2019: Zillionaires like Amazon founder Jeff Bezos who see the ‘colonisation’ of space as an answer to the Earth’s ever threatened resources…
Scientists hit pay dirt with new microbial research technique
A better method for studying microbes in the soil will help scientists understand large-scale environmental cycles Long ago, during the European Renaissance, Leonardo da Vinci wrote that we humans “know more about the movement of celestial bodies than about the…