DALLAS – May 28, 2021 – A study of gene activity in the brain’s hippocampus, led by UT Southwestern researchers, has identified marked differences between the region’s anterior and posterior portions. The findings, published today in Neuron, could shed light on a variety of brain disorders that involve the hippocampus and may eventually help lead to new, targeted treatments.
Tag: Peter O’Donnell Jr. Brain Institute
Exercise Boosts Blood Flow to The Brain, Study Finds
DALLAS – March 23, 2021 – It’s not just your legs and heart that get a workout when you walk briskly; exercise affects your brain as well. A new study by researchers at UT Southwestern shows that when older adults with mild memory loss followed an exercise program for a year, the blood flow to their brains increased. The results were published online today in the Journal of Alzheimer’s Disease.
The a7 Protein is Ready For Its Close-Up
DALLAS – March 17, 2021 – UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes. The work, published online today in Cell, could eventually lead to new pharmaceutical treatments for a large range of diseases or infections including schizophrenia, lung cancer, and even COVID-19.
Riding The Wave to Memory-Forming Genetics
UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The findings, published online this week in Nature Neuroscience, could eventually be used to develop novel therapies for people with memory loss disorders such as Alzheimer’s disease and other forms of dementia.
Hope For Children With Bow Hunter Syndrome
DALLAS – Feb. 11, 2021 – Fusing the neck’s top two vertebrae can prevent repeat strokes in children with bow hunter syndrome, a rare condition that affects a handful of U.S. pediatric patients each year, UT Southwestern researchers suggest in a recent study. The finding, published online in Child’s Nervous System, offers a new way to treat these children and protect them from potentially lifelong neurological consequences.
Bringing Bad Proteins Back Into The Fold
DALLAS – Feb. 11, 2021 – A study led by UT Southwestern has identified a mechanism that controls the activity of proteins known as chaperones, which guide proteins to fold into the right shapes. The findings, published online today in Nature Communications, could shed light on hundreds of degenerative and neurodegenerative diseases caused by protein misfolding, such as Alzheimer’s, Parkinson’s, and Huntington’s, potentially leading to new treatments for these devastating conditions.
Protein That Can Be Toxic in The Heart And Nerves May Help Prevent Alzheimer’s
A protein that wreaks havoc in the nerves and heart when it clumps together can prevent the formation of toxic protein clumps associated with Alzheimer’s disease, a new study led by a UT Southwestern researcher shows. The findings, published recently in the Journal of Biological Chemistry, could lead to new treatments for this brain-ravaging condition, which currently has no truly effective therapies and no cure.
Scientists Identify New Gene Involved In Autism Spectrum Disorder
DALLAS – Dec. 22, 2020 – UT Southwestern scientists have adapted a classic research technique called forward genetics to identify new genes involved in autism spectrum disorder (ASD). In a study published this week in eLife, the researchers used this approach in mice to find one such gene called KDM5A.
Dallas Heart Study Yields New Insights About Depression
DALLAS – Dec. 14, 2020 – Recently published UT Southwestern research reveals new insights about risk factors for depression based on data from a landmark longitudinal study focused on heart disease.
How The Brain Remembers Right Place, Right Time
DALLAS – Dec. 8, 2020 – Two studies led by UT Southwestern researchers shed new light on how the brain encodes time and place into memories. The findings, published recently in PNAS and Science, not only add to the body of fundamental research on memory, but could eventually provide the basis for new treatments to combat memory loss from conditions such as traumatic brain injury or Alzheimer’s disease.