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UrduGRAND RAPIDS, Mich. (JULY 30, 2021) — The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight — not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today in Science Advances.
Tag: UVA
Brain sensor offers Alzheimer’s answers
Scientists have found an explanation for why Alzheimer’s drugs have limited effectiveness and why patients get much worse after going off of them.
Cold sores: Discovery reveals how stress, illness and even sunburn trigger flareups
The finding could lead to new ways to prevent cold sores and herpes-related eye disease from reoccurring, the researchers report.
Cancer’s dangerous renovations to our chromosomes revealed
Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, new research reveals.
New tools to improve care for cancer that has spread to the brain
The tools will help doctors and patients make better-informed treatment decisions, enhance the care of brain metastases, and enable hospitals to improve the coordination and effectiveness of their interdisciplinary treatment programs.
Genetic differences in fat shape men and women’s health risks
New findings about body fat help explain the differing health risks men and women face – and set the stage for better, more targeted treatments.
HIV drugs could prevent diabetes, study suggests
Patients taking drugs called NRTIs to treat HIV and hepatitis B had a 33% lower risk of developing diabetes.
Concussion discovery reveals dire, unknown effects of even mild brain injury
Even mild concussions cause severe and long-lasting impairments in the brain’s ability to clean itself, and this may seed it for Alzheimer’s, dementia and other neurodegenerative problems.
American Heart Association Honors UVA Endocrinologist for Life’s Work on High Blood Pressure
Robert M. Carey, MD, has been named a Distinguished Scientist of the American Heart Association for his “extraordinary contributions” to cardiovascular research.
Strokes in babies are surprisingly common. Here’s how the body rushes to the rescue.
New research is shedding light on the development of the brain’s immune defenses – and how those defenses respond to strokes that strike one in 4,000 babies in the first month of life.
Women surgeons earn their cut of NIH funding – and then some
Women are underrepresented in academic surgery, but women surgeons are earning a disproportionate share of research grants from the National Institutes of Health, a new study has found.
When can kids return to sports after COVID-19? Doctors weigh in
Pediatric cardiologists are offering important advice on if and when it is safe for children and teens to return to playing sports after recovering from COVID-19.
UVA pioneers study of genetic diseases with quantum computers
Scientists are harnessing the mind-bending potential of quantum computers to help us understand genetic diseases – even before quantum computers are a thing. ]
Brain Cancer: UVA IDs Gene Responsible for Deadly Glioblastoma
The discovery of the oncogene responsible for glioblastoma could be the brain tumor’s Achilles’ heel, one researcher says.
Single-Dose Flu Drug Reduces Spread Within Households
Only 1.9% of uninfected household contacts who took a single dose of baloxavir marboxil came down with the flu.
Discovery reveals how plants make cellulose for strength and growth
The new discovery unveils the molecular machinery that plants use to weave cellulose chains into cable-like structures called “microfibrils.”
Lack of lockdown increased COVID-19 deaths in Sweden
Sweden’s controversial decision not to lock down during COVID-19 produced more deaths and greater healthcare demand than seen in countries with earlier, more stringent interventions, a new analysis finds.
Exercise can slow or prevent vision loss, study finds
Exercise can slow or prevent the development of macular degeneration and may benefit other common causes of vision loss, such as glaucoma and diabetic retinopathy, new research suggests.
Blood test at COVID-19 diagnosis can predict disease severity
In addition to its predictive value, the discovery could lead to new treatments to prevent deadly cytokine storms. It also may help explain why diabetes contributes to worse outcomes in patients with COVID-19.
Focused ultrasound shows promise against deadliest brain tumor
An innovative use of focused ultrasound is showing promise against glioblastoma, the deadliest brain tumor, and could prove useful against other difficult-to-treat cancers.
COVID-19 Collaboration Reducing Infections in Long-Term Care Facilities
A collaborative program developed at UVA Health to work with local long-term care facilities to control COVID-19 is saving lives and offers a model for communities across the country, a new scientific paper reports.
Essential key to hearing sensitivity discovered in inner ear
New research is shedding light on the biological architecture that lets us hear – and on a genetic disorder that causes both deafness and blindness.
Spinal cord injuries: Scientists probe individual cells to find better treatments
Two top scientists are seeking answers to questions about spinal cord injuries that have long frustrated the development of effective treatments.
Genetics Researchers Find Easy Way to Improve Cancer Outcomes
By mining a vast trove of genetic data,researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients. The researchers have identified inherited variations in our genes that affect how well a patient will do after diagnosis and during treatment.
Understanding How COVID-19 Affects Children Vital to Slowing Pandemic, Doctors Say
Though COVID-19 so far appears to be largely sparing children, researchers are cautioning that it is critical to understand how the virus affects kids to model the pandemic accurately, limit the disease’s spread and ensure the youngest patients get the care they need.
Discovered: Why obesity causes high blood pressure — and potential ways to fix it
The researchers have already confirmed their discovery in human tissue samples and used it to reverse high blood pressure in lab mice.
Breastfeeding Guide Aims to Help Docs Ease Moms Through Tough 1st Week
A new guide seeks to ensure healthcare providers are ready to help new mothers with the challenging first week of breastfeeding – and to address gaps in knowledge and support created in previous decades when breastfeeding was far less common.
Major Asian Gene Study to Help Doctors Battle Disease
“Under-representation of Asian populations in genetic studies has meant that medical relevance for more than half of the human population is reduced,” one researcher said.
Potential Way to Halt Blinding Macular Degeneration Identified
It would be the first treatment for “dry” age-related macular degeneration and could significantly improve treatment for wet AMD.
Fertilization discovery reveals new role for the egg, could lead to new male contraceptive
An unexpected discovery about fertilization reveals new insights on how sperm and egg fuse and could have major implications for couples battling infertility – and may lead to a future male contraceptive.
Depression, Anxiety Linked to Opioid Use in Women With Breast Cancer
The findings should encourage doctors to better manage mental health in patients with breast cancer and spur care providers to consider alternative pain management such as physical therapy, massage and acupuncture, the researchers say.
Depression, Anxiety Linked to Opioid Use in Women With Breast Cancer
The findings should encourage doctors to better manage mental health in patients with breast cancer and spur care providers to consider alternative pain management such as physical therapy, massage and acupuncture, the researchers say.