Two New Artificial Intelligence Models Seek to Make MRI More Accurate, Reliable

Two new models, developed by researchers in the lab of Li Wang, PhD, associate professor of radiology in the UNC School of Medicine, can produce more accurate and reliable analysis of brain structures, which is critical for early detection, medical diagnosis, and neurological research.

Staying sharp: Study explores how brain changes may affect financial skills

A new paper co-written by faculty at Binghamton University, State University of New York sheds light on how age-related changes may affect the way we handle finances — and how we can stay sharp as we age.

FAU Acquires State-of-the-Art MRI System to Advance Research Capabilities

FAU has added a new state-of-the-art Magnetic Resonance Imaging (MRI) system to its research infrastructure. This cutting-edge technology marks a transformative step forward for FAU’s research capabilities, enabling groundbreaking studies in neuroscience, clinical health and medical advancements.

Researchers solve medical mystery of neurological symptoms in kids

Researchers at WashU Medicine collaborated with an international team of doctors and scientists to identify the cause of a rare disorder involving intellectual disability and brain malformations. The team found a link between the child’s neurological symptoms and a genetic change that affects how proteins are properly folded within cells, providing the parents with a molecular diagnosis and identifying an entirely new type of genetic disorder. The findings are published in Science.

Dramatic Drop in Marijuana Use Among U.S. Youth Over a Decade: (2011 to 2021)

Among 88,183 U.S. high school students, marijuana use declined from 23.1% in 2011 to 15.8% in 2021, with first-time use before age 13 dropping from 8.1% to 4.9%. In 2021, use was highest among 12th graders (22.4%) and 11th graders (18.7%). Notably, girls (17.8%) surpassed boys (13.6%) in reported use in 2021, reversing past trends. While Asian, Hispanic, and white adolescents saw declines, Black adolescents had a higher usage rate of 20.5% in 2021, indicating ongoing racial disparities.

Brain Imaging of Neuromelanin May be Key to Understanding Extensive Substance Use

A study that used a specialized type of magnetic resonance imaging (MRI), named neuromelanin-sensitive MRI, showed that this type of MRI signal was increased in regions of the midbrain in young adults ages 20 to 24 who had an extensive alcohol and drug use history. The findings are published early online in the American Journal of Psychiatry.

Challenging Current Understanding, Study Reveals Rapid Release of Dopamine Not Needed for Initiating Movement

At a glance: Study in mice reveals rapid release of dopamine is not needed for initiating movement but is important for activities related to reward-seeking and motivation. The findings help explain why the widely used Parkinson’s drug levodopa improves movement-related symptoms but often fails to ameliorate some cognitive ones. The work may inform the development of new therapies that restore both slow and fast dopamine action to treat multiple symptoms.

UTSW study explores link between high school IQ and alcohol use

A person’s IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism. Participants with higher IQ levels were significantly more likely to be moderate or heavy drinkers, as opposed to abstaining.

Novel motion simulator reveals key role of airflow in rodent navigation

With the assistance of a novel motion simulator, researchers at Bar-Ilan University in Israel have discovered that rats rely on airflow to navigate their surroundings. When they move, the flow of air relative to their bodies provides crucial information, complementary to their sense of balance, to perceive their own motion in space. This might explain their agility in the dark as they scurry through pipes and tunnels, turn corners, and effortlessly travel from one location to another, all while knowing exactly where they’re headed.

Autism Spectrum Disorders Linked to Neurotransmitter Switching in the Brain

Neurobiologists studying the emergence of autism spectrum disorders have found evidence of altered early development of the nervous system. They linked environmentally induced forms of ASD to changes in neurotransmitters, the chemical messengers that allow neurons to communicate with each other.

Natural grass may pose greater risk for football concussions

Young football players who sustained a head-to-ground concussion practicing or playing games on natural grass experienced more symptoms – and significantly higher severity – than those who suffered concussions on artificial turf, researchers at UT Southwestern Medical Center found.

Fentanyl May Increase or Decrease Oxygen Levels Depending on Dosage

Article title: Oxygen fluctuations in the brain and periphery induced by intravenous fentanyl: effects of dose and drug experience Authors: Shinbe Choi, Michael R. Noya, Eugene A. Kiyatkin From the authors: “We report that fentanyl’s effects are highly dose-dependent, drawing…

New visual technique could advance early detection of neurodegenerative diseases

Researchers at the University of Minnesota, have developed a new visual diagnostic technique that can be used to advance early detection for neurodegenerative diseases like Parkinson’s disease and similar diseases that affect animals, including Chronic Wasting Disease in deer.

Researchers Identify Potential Therapeutic Target for Management of Thirst Disorders

In a recent mouse-model study, published in Nature Neuroscience, researchers at University Hospitals (UH), Harrington Discovery Institute at UH, and Case Western Reserve University have now found that the cerebellum also controls thirst, a major function necessary for survival. Specifically, the research team found that a hormone, asprosin, crosses from the periphery into the brain to activate Purkinje neurons in the cerebellum. This leads to an enhanced drive to seek and drink water.

Toddlers’ brains show significant growth in cognitive skills by 16 months, study finds

Toddlers engage more regions of their brains around 16-months to help them develop important cognitive skills enabling them to follow simple instructions and control impulses. Findings from the study, led by the Universities of Bristol and Oxford, and published in Imaging Neuroscience, suggests 16 months is a critical period for brain development.

Chemotherapy disrupts gut microbiome in patients with breast cancer

“For the first time ever, our Intelligut Study found that the gut microbiome has been implicated in cognitive side effects of chemotherapy in humans,” said senior author Leah Pyter, associate professor of psychiatry and neuroscience with The Ohio State University Wexner Medical Center and College of Medicine.

Study Challenges ED Protocols for Geriatric Head Injuries and Blood Thinners

Out of 3,425 patients enrolled in the study, 0.4% (13 patients) experienced a delayed intracranial hemorrhage, a significantly lower rate than previously reported (7.2%).

Alcohol misuse can disrupt gut microbiota, causing inflammation that leads to organ damage

Alcohol researchers have long known that excessive drinking can cause damage to the liver, pancreas, heart, muscle, bone, and brain. However, only a subset of patients with alcohol use disorder (AUD) appear to develop organ damage. New research shows that alcohol-induced gut inflammation is the missing link between unhealthy drinking and organ damage among certain AUD patients.

Alzheimer’s Awareness Month: Virginia Tech researchers work toward better treatments

Alzheimer’s disease, a deadly brain disease than can cause loss of memory and mobility, affects millions of lives daily. June marks Alzheimer’s and Brain Awareness Month, and Virginia Tech researchers are engaged in research meant to advance treatment for Alzheimer’s disease and assist caregivers of loved ones with dementia.

Tricking the Brain’s inner GPS: Grid cells responses to the illusion of self-location

Dr. Hyuk-June Moon from the Bionics Research Center at the Korea Institute of Science and Technology (KIST), in collaboration with Prof. Olaf Blanke’s team at the Swiss Federal Institute of Technology Lausanne (EPFL), has successfully induced self-location illusions with multi-sensory virtual reality (VR) in the MRI scanner and observed corresponding changes in the human brain’s grid cell activity.

Everyday social interactions predict language development in infants

In a study published April 8 in Current Biology, University of Washington researchers found that when the adult talked and played socially with a 5-month-old baby, the baby’s brain activity particularly increased in regions responsible for attention — and the level of this type of activity predicted enhanced language development at later ages.

Gene therapy offers hope for giant axonal neuropathy patients

A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports. Findings from the phase one clinical trial, published in the New England Journal of Medicine, could offer hope for patients with this rare condition and a host of other neurological diseases.