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UrduThe Online First edition of the upcoming April issue of The Lancet, one of the world’s leading medical journals, features an article on Health People’s new diabetes report, “Wasted Billions, Wasted Health.” (https://tinyurl.com/r4mcgrz)
Tag: Diabetes
Loss of Enzyme in Fat Tissue Leads to Improved Insulin Sensitivity in Liver
Article title: DPP4 deletion in adipose tissue improves hepatic insulin sensitivity in diet-induced obesity Authors: Tania Romacho, Henrike Sell, Ira Indrakusuma, Diana Roehrborn, Tamara R. Castañeda, Tomas Jelenik, Daniel Markgraf, Sonja Hartwig, Jürgen Weiß, Hadi Al-Hasani, Michael Roden, Jürgen Eckel…
Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
The insulin-producing beta cells in the pancreas unwittingly produce a signal that may aid their own demise in Type 1 diabetes, according to a study of the lipid signals that drive macrophage cells in the body to two different phenotypes of activated immune cells.
Bariatric surgery effective against early-onset obesity too
Surgical treatment of obesity is as effective for individuals who developed the disorder early, by the age of 20, as for those who have developed obesity later in life, a study from the University of Gothenburg shows.
Patients frequently refuse insulin therapy, delaying blood sugar control
Patients with type 2 diabetes who have high levels of blood sugar are at greater risk of serious complications such as chronic kidney disease, heart disease and blindness.
The potentially deadly paradox of diabetes management
Diabetes affects nearly 1 in 10 adults in the U.S., of these millions, more than 90% have Type 2 diabetes. Controlling blood sugar and glycosylated hemoglobin levels ― or HbA1c, which is sometimes referred to as A1C ― is key to diabetes management and necessary to prevent its immediate and long-term complications. However, new Mayo Clinic research shows that diabetes management may be dangerously misaligned.
Comer Children’s and the Kovler Diabetes Center lead the way in monogenic diabetes care, research
Researchers at the University of Chicago Medicine are leading the charge to educate clinicians and families about monogenic diabetes, a rare and frequently misdiagnosed subset of the disease.
Mount Sinai Discovers New Drug Combo to Induce High Rates of Human Beta Cell Regeneration
Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells—the cells in the pancreas that produce insulin—without harming most other cells in the body. The result is an important step toward a diabetes treatment that restores the body’s ability to produce insulin.
NEW REPORT: NEW YORK STATE’S $4 BILLION MEDICAID GAP FUELED BY HIGHEST-IN-NATION “EXCESS DIABETES COSTS”
Proven Strategies to Slash Type-2 Diabetes Costs Ignored by State While Medicaid Deficit Explodes
Human Gut-in-a-Dish Model Helps Define ‘Leaky Gut,’ and Outline a Pathway to Treatment
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
Drug to Improve Fetal Growth May Impair Baby’s Postnatal Blood Pressure, Sugar Levels
Research suggests that a drug recently assessed as a potential treatment for fetal growth restriction may cause high blood pressure and raise blood sugar levels in offspring. The study urges practitioners to consider both short- and long-term effects when treating people with this pregnancy complication.
New president officially recognized at the Association of Diabetes Care & Education Specialists
Kellie Antinori-Lent, MSN, RN, ACNS-BC, BC-ADM, CDCES, FADCES was officially recognized last week at the meeting of the board of directors as the 2020 president of the newly rebranded Association of Diabetes Care & Education Specialists (ADCES).
Researchers successfully test coin-sized smart insulin patch, potential diabetes treatment
UCLA bioengineers and colleagues at UNC School of Medicine and MIT have further developed a smart insulin-delivery patch that could one day monitor and manage glucose levels in people with diabetes and deliver the necessary insulin dosage.
High-Tech Printing May Help Eliminate Painful Shots
Painful hypodermic needles may not be needed in the future to give shots, inject drugs and get blood samples. With 4D printing, Rutgers engineers have created tiny needles that mimic parasites that attach to skin and could replace hypodermic needles, according to a study in the journal Advanced Functional Materials.
Changes in Muscle Nerve Activity in Type 2 Diabetes May Increase Heart Disease Risk
Article title: Augmented pressor and sympathoexcitatory responses to the onset of isometric handgrip in patients with type 2 diabetes Authors: Jennifer R. Vranish, Seth W. Holwerda, Jasdeep Kaur, Paul J. Fadel From the authors: “[Type 2 diabetes] is associated with…
Your gums reveal your diet
Sweet soft drinks and lots of sugar increase the risk of both dental cavities and inflammation of the gums – known as periodontal diseases – and if this is the case, then healthy eating habits should be prioritised even more.
An egg a day not tied to risk of heart disease
The controversy about whether eggs are good or bad for your heart health may be solved, and about one a day is fine. A team of researchers from the Population Health Research Institute of McMaster University and Hamilton Health Sciences found the answer by analyzing data from three large, long-term multinational studies.
Researchers Identify Opportunities to Advance Genomic Medicine
New Study Highlights Milestones in the History of Genetic Discoveries; Equitable and Fair Access Required to Address Disparities
Former AADE rebrands as Association of Diabetes Care & Education Specialists
The former American Association of Diabetes Educators is now the Association of Diabetes Care & Education Specialists (ADCES). The rebranding reflects the association’s shift from referencing the specialty title as “diabetes educator” to the more comprehensive “diabetes care and education specialist.” The new title more accurately signifies the range of expertise diabetes care and education specialists provide to people with diabetes, prediabetes and cardiometabolic conditions, the health care system, payers and providers.
Study: Neuron Found in Mice Could Have Implications for Effective Diet Drugs
A cell found in mice may be able to stop feeding in humans without subsequential nauseating effects as well as influence the long term intake of food.
Hohe Insulinkosten sind für Diabetespatienten lebensbedrohlich
Die am häufigsten verwendeten Formen von Insulin kosten in den USA 10-mal mehr als in jedem anderen Industrieland, wie aus einem Kommentar in Mayo Clinic Proceedings hervorgeht.
Custo elevado da insulina pode significar vida ou morte para pacientes diabéticos
As formas mais comumente usadas de insulina custam 10 vezes mais nos EUA que em qualquer outro país desenvolvido, de acordo com um comentário publicado na Mayo Clinic Proceedings.
An Out-of-the-Box Attack on Diabetes
A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by scientists at the U.S. Department of Energy’s Pacific Northwest National Laboratory and Indiana University School of Medicine.
Genetic Differences Help Distinguish Type 1 Diabetes in Children from “Type 1.5” Diabetes in Adults
A multi-center team of researchers led by Children’s Hospital of Philadelphia (CHOP) has discovered a genetic signature that could help distinguish an adult-onset form of diabetes sharing many type 1 diabetes (T1D) characteristics from pediatric-onset T1D, opening the door to potentially more straightforward diagnostic tests for the adult condition and improving responses by ensuring patients receive the most appropriate treatment.
Costo elevado de la insulina conlleva implicaciones de vida o muerte para pacientes diabéticos
ROCHESTER, Minnesota: El costo de los tipos de insulina más frecuentemente usados es en Estados Unidos 10 veces mayor que en el resto de países del mundo desarrollado, expone un comentario en Mayo Clinic Proceedings. Este costo prohibitivo es la causa para que algunos pacientes estadounidenses con diabetes tipo 1 racionen la cantidad de insulina que se administran y, consecuentemente, afronten implicaciones de vida o muerte.
High cost of insulin has life-or-death implications for diabetic patients
The most commonly used forms of insulin cost 10 times more in the U.S. than in any other developed country, according to a commentary in Mayo Clinic Proceedings. This prohibitive cost is causing some U.S. patients with Type 1 diabetes to ration the amount of insulin they use, with life-threatening implications.
Reimagining your New Year’s resolutions
As the new year approaches, AADE suggests the following ways for people with diabetes to start the year healthy and stick with it.
Diabetes can independently lead to heart failure, population study shows
Heart problems are a common development for people with diabetes. In fact, about 33% of people in the U.S. admitted to the hospital for heart failure also have diabetes. Heart failure may be the result of a co-condition, such as hypertension or coronary heart disease, but not always.
A study published in Mayo Clinic Proceedings, Diabetes Mellitus Is an Independent Predictor for the Development of Heart Failure: A Population Study, examines the idea of diabetic cardiomyopathy and heart failure from the effects of diabetes alone.
$1.7 M grant to Wayne State College of Engineering aims to improve oral delivery of insulin
With the help of a $1.7 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health, a team of researchers in Wayne State’s College of Engineering will explore ways to address urgent need for a safe and efficient oral delivery technology for insulin to improve the lives of diabetes patients.
First-ever quality measures aim to reduce diabetes complications
The Endocrine Society and Avalere Health introduced the first-ever quality measures to help healthcare providers assess how well they identify and care for older adults at greater risk of hypoglycemia—low blood sugar that can be a dangerous complication of diabetes treatment.
“Seeing others suffer is too stressful”: Why people buy, trade, donate medications on the black market
Altruism and a lack of access and affordability are three reasons why people with chronic illnesses are turning to the “black market” for medicines and supplies, new research shows. Scientists at University of Utah Health and University of Colorado ran surveys to understand why individuals are looking beyond pharmacies and medical equipment companies to meet essential needs. The reasons listed were many but centered on a single theme: traditional healthcare is failing them.
Taming chronic inflammation may reduce illness, save lives
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.
Can the state of Alabama conquer its biggest health challenges? It’s a Grand Challenge, and one state university is determined to prevail
For far too long, Alabama’s residents have seen their health statuses languish when compared to those of other states. Often, Alabama is a punchline when it comes to obesity, diabetes and the overall health of its people. But the consequences, unfortunately, are counted in decreased quality of life, increased health costs and lives lost — hardly a laughing matter.
Common Diabetes Medications Tested for Anti-Aging Effects
Two drugs already on the market to treat type two diabetes are being tested in nonhuman primates to see if they can impact the aging process. Researchers dosed marmosets with Metformin and Acarbose and found no adverse side effects
Helper Protein Worsens Diabetic Eye Disease
In a recent study using mice, lab-grown human retinal cells and patient samples, Johns Hopkins Medicine scientists say they found evidence of a new pathway that may contribute to degeneration of the light sensitive tissue at the back of the eye. The findings, they conclude, bring scientists a step closer to developing new drugs for a central vision-destroying complication of diabetes that affects an estimated 750,000 Americans.
Hibernating Mammals Arouse Hope for Genetic Solutions to Obesity, Metabolic Diseases
University of Utah Health scientists say they have detected new genetic clues about hibernation that could lead to better understanding and treatment of obesity and metabolic disorders that afflict millions of people worldwide.
Diabetes course inspires healthy choices in high-schoolers
UW Medicine’s genome sciences team creates curriculum that makes information personal to youths. It’s being tested in 50 classrooms.
The cause of chewy chicken meat
Wooden breast syndrome hurts the poultry industry by making chicken meat chewy. Researchers found gene expression irregularities suggesting it’s a metabolic disorder and could lead to short-term solutions. The findings may also inform human health research on metabolic syndromes such as diabetes.
Sexual dysfunction common in Type 1 Diabetes patients, study says
A recent study published in Muscle & Nerve explored the prevalence of male sexual dysfunction in type 1 diabetes. Written by Ana Calzada-Reyes of Havana, Cuba, the study investigated the “prevalence of sexual dysfunction in a sample of males with type 1 diabetes.”
Prior exposure to pollutants could underlie increased diabetes risk of Indian immigrants
Researchers reporting in ACS’ Environmental Science & Technology have linked high levels of DDT in Indian immigrants in the U.S. with risk factors for diabetes.
People with type 1 diabetes still struggle with blood sugar control despite continuous glucose monitoring (CGM)
Some continuous glucose monitoring (CGM) alarm features and settings may achieve better blood sugar control for people with type 1 diabetes, according to a study published in the Journal of the Endocrine Society.
Diabetes, Heart Problems And Redundant Imaging Scans Are Among Johns Hopkins-Led Performance Improvement Topics on ‘High-Value Care’
Experts from 80 medical centers in the U.S., Canada and Norway will convene Nov. 15–17 in Baltimore, Maryland, to share best practices and performance improvement initiatives designed to reduce unnecessary tests, treatments and procedures and improve the overall value of health care.
Participants Sought for National Trial to Test Benefits of a Healthy Lifestyle
The Enhanced Lifestyles for Metabolic Syndrome (ELM) Trial, a multisite test of two lifestyle treatments for a dangerous cluster of sub-disease indicators called the metabolic syndrome, is now accepting applicants at five medical centers around the country.
Beating diabetes:
Every five minutes, someone in Australia is diagnosed with diabetes. It’s Australia’s fastest growing chronic condition, but as its prevalence grows more people are adding dietary supplements to their diets in the hope of reducing their risk of the disease. But how effective are dietary supplements?
Estudio de Mayo Clinic descubre que hombres y mujeres tienen diferente percepción de su propia salud
Un estudio de Mayo Clinic publicado en American Journal of Health Behavior investiga las diferencias entre hombres y mujeres en cuanto a la percepción de su propia salud. El estudio descubrió que el sexo de la persona influye sobre la seguridad de poder mantener buenos hábitos de salud.
Researchers discover a new way in which insulin interacts with its receptor
The biological actions of insulin are mediated by its receptor—the insulin receptor—which is localized on the cell surface. In a new study, researchers from Germany, Canada, and Finland show how insulin interacts with its receptor at a second binding site. The scientists hope that these new details concerning insulin–receptor interactions will ultimately expand the current models of insulin binding to its receptor and pave the way towards new approaches to structure-based drug design.
Mount Sinai Researcher’s Examine the Metabolic Effects of an Oral Blood Cancer Drug
Recent study found that an effective blood cancer treatment was associated with weight gain, obesity, and increased systolic blood pressure
PRESS CONFERENCE AND RALLY TO FIGHT MASS DIABETES AMPUTATIONS
On World Diabetes Day, November 14, as the New York City Council prepares to pass new diabetes-related legislation, South Bronx-based Health People: Community Preventative Health Institute will host a “Pray-In” at the New York State Department of Health’s New York City offices to mourn the untold number of needless diabetes-related amputations in the city and state. The Pray-In will also highlight the need for better data tracking of diabetes-related amputations and other complications.
Better Biosensor Technology Created for Stem Cells
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer’s and Parkinson’s diseases and other neurological disorders. The technology, which features a unique graphene and gold-based platform and high-tech imaging, monitors the fate of stem cells by detecting genetic material (RNA) involved in turning such cells into brain cells (neurons), according to a study in the journal Nano Letters.
Teaching Preschool Caregivers about Healthy Behaviors May Promote Healthier Lifestyle in Some High-Risk Groups
Study Shows Vascular Ultrasounds and Adhering to Interventional Education in Underserved Communities can Improve Health among Parents and School Staff