Body weight trends upwards after breast reduction surgery in teens

Many adolescents and young women gain weight in the years after breast reduction surgery – particularly those who were at a healthy body mass index (BMI) before surgery, reports a paper in the February issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Weight-Loss Surgery Lowers Risk of Developing Complications of Liver Disease in Patients with Cirrhosis and Obesity

A Cleveland Clinic study shows that patients with obesity and fatty liver-related cirrhosis who had bariatric (weight-loss) surgery significantly lowered their future risk of developing serious liver complications compared with patients who received medical therapy alone. The results were published in Nature Medicine journal.

Diabetes Drug Appears to Fight Lung Cancer — But Only in Overweight or Obese Patients

A widely accessible drug commonly used to control blood glucose levels in diabetic patients has the potential to strengthen the effects of immunotherapy and improve recurrence-free survival in people with lung cancer who are overweight or obese, according to a recently published article in the Journal of the National Cancer Institute.

Routine blood test can identify laboring women at risk for preeclampsia, prompt interventions to protect mom and baby

A simple blood test could help doctors identify women in labor who are at risk for preeclampsia — a leading cause of maternal death — and take precautions to prevent it, according to research presented at the ANESTHESIOLOGY® 2024 annual meeting.

Bariatric Surgery Is More Cost Effective Than Newer Weight Loss Drugs Alone

Newer weight loss drugs are cost effective in the long term only when combined with bariatric weight loss surgery, according to a study presented at the American College of Surgeons (ACS) Clinical Congress 2024 in San Francisco, California. Further, a second study presented at the meeting found that this increasingly popular class of weight loss drugs, called glucagon-like peptide-1 receptor agonists, or GLP-1 RA, appears safe and may be a novel approach to treating obesity when used before bariatric surgery.

Alarming Surge: Global Crisis of Childhood Overweight and Obesity

Since 1990, childhood obesity has nearly doubled globally, with the U.S. at the forefront. In Southern Europe, 10-15% of children are obese, while Asia has nearly half of all overweight kids under 5. Nearly 70% of the average U.S. child’s diet consists of ultra-processed foods, which are increasingly consumed by children under 24 months, raising obesity risks and reducing immunological protection. Addressing pediatric obesity requires a multifaceted approach from tackling the influence of social media and advertising on children’s food choices to increasing physical activity.

Proteins prohibitins can become new targets for drugs from obesity

Scientists from Immanuel Kant Baltic Federal University analyzed scientific works dedicated to the role of proteins prohibitins in the development of obesity. It turned out that these proteins promote development of inflammation both in separate cells and the whole organism. This happens because prohibitins stimulate emission of anti-inflammatory substances by immune cells, and also participate in destruction of mitochondria damaged during oxidative stress. Obtained information points to the fact that prohibitins can become targets for medicine aimed at struggle with obesity consequences. Results of the research are published in the magazine Frontiers in Molecular Biosciences.

American Society of Nephrology Releases Kidney Health Guidance on the Management of Obesity in Persons with Kidney Diseases

To promote high-quality, person-directed care across the spectrum of kidney health and diseases the American Society of Nephrology (ASN) is releasing its inaugural Kidney Health Guidance (KHG) on the Management of Obesity in Persons Living with Kidney Diseases in the Journal of the American Society of Nephrology (JASN) on September 18, 2024.

Endurance Exercise without Weight Loss May Reduce Body Fat

Participating in a high volume of exercise over a short period of time, such as cycling hundreds of miles in a few days, could reduce body fat levels without weight loss. The first-of-its-kind study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism and has been chosen as an APSselect article for September.

First Patient Dosed in Phase 2 Clinical Study of Palatin’s Bremelanotide Co-Administered with Tirzepatide (GLP-1) for the Treatment of Obesity

Palatin Technologies, Inc. (NYSE American: PTN), a biopharmaceutical company developing first-in-class medicines based on molecules that modulate the activity of the melanocortin receptor system, today announced that patient dosing has started for the clinical study entitled: BMT-801: A Phase II, Randomized, Double-Blind, Placebo-Controlled, Clinical Study Investigating the Safety, Tolerability, and Effectiveness of the Co-Administration of Bremelanotide with Tirzepatide (GLP-1/GIP) for the Treatment of Obesity (ClinicalTrials.gov Identifier: NCT06565611).

Combining Two Diabetes Drugs Helps Promote Weight Loss and Blood Sugar Control

New research finds a combination of drugs improves weight loss, glucose control and insulin resistance better than either drug alone. Using two diabetes medications together, such as a semaglutide like Ozempic or Rybelsus, with a second, newer class of drug, may offer a noninvasive solution to help people with Type 2 diabetes lose weight and manage their condition without the need for bariatric surgery.

Joslin Diabetes Center Investigator Rohit N. Kulkarni, MD, PhD, Awarded $10 Million NIH/NIDDK Grant for Pioneering Diabetes and Obesity Research

Rohit N. Kulkarni, MD, PhD, the Diabetes Research and Wellness Foundation Endowed Chair and Co-Head of the Section on Islet & Regenerative Biology at Joslin Diabetes Center, has been awarded $9,920,607 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH).

Uncontrolled Hypertension: The Old ‘Silent Killer’ is Alive and Well

High blood pressure affects about 45% of U.S. adults. In the 1970s, only about 50% of patients were aware of their hypertension. Today, 54% are aware of their high blood pressure, 40% are actively treated and 21% are actively controlled. As such, researchers alert health care providers that the old “silent killer” is alive and well.

Rutgers Names Nationally Recognized Clinician-Scientist in Obesity and Nonalcoholic Fatty Liver Disease as New Chair of Medicine

Jeanne M. Clark, a board-certified internal medicine physician with extensive research experience and a nationally renowned expert in the epidemiology and treatment of obesity, will join Rutgers Robert Wood Johnson Medical School as the Henry Rutgers Professor and chair of the Department of Medicine.

New Cedars-Sinai Study Investigates Shifting Trends in GLP-1RA Prescription

Investigators at Cedars-Sinai and other institutions conducted a nationwide, population-based study to identify trends in the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs)—prescription medications sold under popular drug names like Ozempic and Wegovy—in the United States.