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UrduPeople who have just one or two drinks per day are not protected against endocrine conditions such as obesity and type 2 diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Tag: Obesity
UCSF Internal Medicine Specialist to be Celebrated for Diabetes Epidemiology Research
Alka M. Kanaya, MD, UC San Francisco primary care physician and researcher, is being recognized with the 2023 Kelly West Award for Outstanding Achievement in Epidemiology from the American Diabetes Association (ADA). The award recognizes significant contributions to the field of diabetes epidemiology.
Loyola Medicine Improves Health Equity by Increasing Access to Kidney Transplants for Patients with Obesity
Loyola Medicine’s advanced robotic surgery program makes it one of the few hospitals in the country to offer kidney transplantation to patients with obesity.
Gaps remain in identifying, treating obesity despite new treatment options
By being undiagnosed or untreated, a significant fraction of people with obesity or overweight are not getting the recommended care, despite an increase in new treatment options, according to research being presented on June 17 at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
Employees with obesity may have higher loss of work productivity than those with normal weight
People with obesity may have lower work productivity due to increased risk of illness, contributing to increased costs for employers, according to industry-supported research being presented Saturday at ENDO 2023, the Endocrine Society’s annual meeting, in Chicago, Ill.
Some breast cancer treatments may limit effectiveness of weight loss medications
Breast cancer medications, called aromatase inhibitors, may lessen the effect of weight loss drugs, according to a new study being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
BMI alone may not be a sufficient indicator of metabolic health
Body mass index (BMI) is not a complete measure of metabolic health, and a high proportion of U.S. adults with normal BMI still have obesity, according to research being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
Body image concerns significantly higher in women living with PCOS
Women living with polycystic ovary syndrome (PCOS) experience greater body image concerns than individuals without the condition, according to research being presented Saturday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
NHS policies on patient’s weight and access to hip replacement surgery are inappropriate, study finds
Weight and body mass index (BMI) policies introduced by NHS commissioning groups in England are inappropriate and worsening health inequalities, according to a new study published in BMC Medicine today [13 June] that analysed nearly 490,000 hip surgeries. With one in ten people likely to need a joint replacement in their lifetime, many thousands of patients are directly affected by these policies.
Blocking Signals from Receptor Involved in Fat Metabolism, Inflammation Improves Fatty Liver and Insulin Resistance in Mice
Article title: Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding Authors: Takuma Yasuda, Norio Harada, Tomonobu Hatoko, Atsuhiko Ichimura, Eri Ikeguchi-Ogura, Yuki Murata, Naoki Wada, Sakura Kiyobayashi, Shunsuke Yamane, Akira Hirasawa, Nobuya…
New research shows an uptick in weight loss surgery among youth in US
More adolescents in the U.S. are undergoing weight loss surgery, according to researchers with UTHealth Houston. The study was published in JAMA Pediatrics.
New Penn Medicine Study Uncovers Key Details of Fat Cells, Advancing Potential Treatments for Obesity, Diabetes
New research has unlocked insights into how “good fat” tissue could potentially be harnessed to combat obesity and remove glucose from the blood, helping to control diabetes. Published today in Science Advances, the work is a collaboration between researchers with the Perelman School of Medicine at the University of Pennsylvania and University of Cambridge, Free University of Brussels and University of East Anglia.
Obesity increases risk of mental disorders throughout life
Being obese significantly increases the chances of also developing mental disorders. This applies to all age groups, with women at higher risk than men for most diseases, as a recent study of the Complexity Science Hub and the Medical University of Vienna shows.
ENDO 2023 press conferences to highlight emerging technology and diabetes research
Researchers will delve into the latest research in diabetes, obesity, reproductive health and other aspects of endocrinology during the Endocrine Society’s ENDO 2023 news conferences June 15-18.
The Mediterranean Diet: Good for your health and your hip pocket
We’ve heard it time and time again – the Mediterranean diet is great for our health. But despite the significant health benefits of this eating plan, a common deterrent is often the expected costs, especially when budgets are tight.
Saturated fatty acids promote immune escape of oral cancers
A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers’ ability to escape from the immune system.
Study Reveals How Fatty Liver Promotes Colorectal Cancer Spread
Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver. Their study, published today in the peer-reviewed journal Cell Metabolism, details the process at the cellular level and could change the way doctors manage the disease in some patients.
Diet has a bigger say on gut microbes than the intestinal defense molecules
Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.
Cleveland Clinic Bariatric Surgeon Receives a 2023 Top Ten Clinical Research Achievement Award from the Clinical Research Forum
A Cleveland Clinic landmark study on obesity and cancer, led by Ali Aminian, M.D., director of Cleveland Clinic’s Bariatric & Metabolic Institute, was recognized with a 2023 Top Ten Clinical Research Achievement Award by the Clinical Research Forum (CR Forum). The award-winning paper, the SPLENDID study that was published in JAMA, also received an additional recognition as a Distinguished Clinical Research Awardee.
More structure, fewer screens makes for healthier kids in the school holidays
Vacation care, sports programs, or performing arts – whatever your child’s interests, researchers say that adding structure to the school holiday is a great way to keep kids healthy and active over the break.
‘Beige fat’ could hold key to age-related metabolism change
New research suggests a strategy to ward off age-related weight gain, which could prevent obesity and associated health disorders like Type 2 diabetes, heart disease and chronic inflammation.
Men and women have different obesity drivers, pointing to the need for tailored interventions
A new study from UCLA researchers finds sex-specific brain signals that appear to confirm that different drivers lead men and women to develop obesity.
Succinate Protects against Obesity, Metabolic Disease through Brown Fat Protein Expression
Article title: Exogenous succinate impacts mouse brown adipose tissue mitochondrial proteome and potentiates body mass reduction induced by liraglutide Authors: Rodrigo S. Gaspar, Jeany Delafiori, Giuliana Zuccoli, Victor Corasolla Carregari, Thais P. Prado, Joseane Morari, Davi Sidarta-Oliveira, Carina S. Solon,…
Obesity treatment could offer dramatic weight loss without surgery or nausea
Imagine getting the benefits of gastric bypass surgery without going under the knife. A new class of potential treatments has done that in lab animals, reducing weight dramatically and lowering blood glucose without side effects, scientists report. They will present their results at ACS Spring 2023.
A Registered Dietitian’s Reaction to the New FDA Proposed Rule on Salt
According to the American Heart Association, roughly 90% of Americans are overdoing it on salt, consuming over twice the daily recommended amount. The U.S. Food and Drug Administration (FDA) announced recently it was proposing a rule to allow the use of salt…
New survey finds COVID-19 pandemic changed public’s view of obesity
Nearly a third of Americans (29%) say COVID-19 made them more worried than ever about having obesity prompting about 28 million people to consider weight-loss methods they hadn’t thought about before the pandemic began, including nearly 6.4 million thought about turning to either weight-loss surgery or taking prescription anti-obesity drugs for the first time, according to a new survey whose findings were published online in the peer-reviewed journal, Surgery for Obesity and Related Diseases (SOARD).
British public back ban on selling junk foods at checkouts study shows
Shoppers join food industry and health experts in backing UK plans to ban high fat, salt and sugar products from checkouts, store entrances and aisle ends
Naturally occurring peptide may tackle the ‘root cause’ of obesity-related conditions
Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).
Mothers’ Obesity Damages Blood-brain Barrier in Offspring, Lean Foster Mothers’ Milk May Be Preventive Tool
Article title: Maternal obesity damages the median eminence blood-brain barrier structure and function in the progeny: the beneficial impact of cross-fostering by lean mothers Authors: Roberta Haddad-Tóvolli, Joseane Morari, Roberta Barbizan, Vanessa C. Bóbbo, Rodrigo S. Carraro, Carina Solon, Nathalia…
Women with Obesity and Type 2 Diabetes May Improve Vascular Insulin Resistance through Weight Loss
Article title: Impact of sex and diet-induced weight loss on vascular insulin sensitivity in type 2 diabetes Authors: Camila Manrique-Acevedo, Rogerio Nogueira Soares, James A. Smith, Lauren K. Park, Katherine Burr, Francisco I. Ramirez-Perez, Neil J. McMillan, Larissa Ferreira-Santos, Neekun…
Precarious work associated with high BMI
A study inks precarious work with increases in body mass index and adds to a growing body of evidence that precarious work may contribute to poor health outcomes.
Cleveland Clinic Study Finds Common Artificial Sweetener Linked to Higher Rates of Heart Attack and Stroke
New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke. Findings were published today in Nature Medicine.
Research network yields significant findings related to obesity
In 2017, Vanderbilt University Medical Center was selected to be one of four U.S. medical centers in a Strategically Focused Research Network (SFRN) on Obesity funded by a four-year, $15 million award from the American Heart Association to study obesity and train future obesity-focused investigators.
Genes that may predict complications from obesity differ between the sexes
In a new study published February 16, 2023, in Nature Genetics, researchers from the University of Chicago characterized the impact of a genetic variant associated with higher cholesterol and triglyceride blood levels in women, suggesting that similar genes might lead to different patterns of fat distribution and obesity-related disease risk for women.
Overweight and Obesity in People With Type 1 Diabetes Nearly Same as General Population
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that Americans with type 1 diabetes had overweight or obesity at almost the same high rates observed in persons without diabetes.
Overweight and obesity prevalent and poorly managed among adults with type 1 diabetes
A brief research report found adults with type 1 diabetes had overweight or obesity at the same rates as adults without diabetes, but only half of these patients received lifestyle recommendations from providers or engaged in lifestyle modification for weight management. The report is published in Annals of Internal Medicine.
The weight of the COVID-19 pandemic
“A potential pathway between obesity and these stressors could be related to weight bias and stigma; there was extensive media coverage highlighting obesity as a potential risk factor for COVID-19 mortality which may have increased weight stigma,” the researchers wrote. The study examined data from nearly 24,000 participants enrolled in the Canadian Longitudinal Study on Aging (CLSA), who were between the ages of 50 and 96 during the first year of the pandemic. The participants completed the CLSA COVID-19 Questionnaire Study, which collected longitudinal data from April to December 2020. The researchers also used data collected before the pandemic to examine if childhood adversity, such as abuse and neglect, was a factor that modified the relationship between obesity and stress.
Study Unravels Interplay Between Sleep, Chronic Pain and Spinal Cord Stimulation
Spinal cord stimulation uses low levels of electricity to relieve pain. A study is the first to measure this treatment’s effects on patients by gauging improvement in insomnia after spinal cord stimulation. Results showed a 30 percent or more improvement of both nighttime and daytime components of insomnia in 39.1 percent of study participants and a 30 percent or more improvement of daytime sleepiness in 28.1 percent of participants. Findings correlated with improvement in disability and depression and revealed associations with sleep and both pain and depression. Results will help clinicians gain a better understanding of the type of patient most likely to benefit from this treatment.
Clemson scientists identify enzyme that reduces diet-induced obesity in humans
Clemson University researchers have identified an enzyme and its products in humans that reduce diet-induced obesity.
Vitamin A May Protect Heart from Some Effects of Obesity
Research in a mouse model of diet-induced obesity found greater disruption to genes involved in heart function when coupled with vitamin A deficiency. The study is published in the American Journal of Physiology-Heart and Circulatory Physiology. It was chosen as an APSselect article for January.
Breast Cancer Risk Calculator Can Assess Risk of Advanced Breast Cancer
Breast cancer is now the leading cause of global cancer incidence among women but determining who will develop breast cancer is still a challenge for the medical community. A new tool, developed by researchers from UCSF and several other medical institutions, helps to calculate risk for those who may develop advanced breast cancer that goes undiagnosed despite regular screenings.
Study reveals obesity-related trigger that can lead to diabetes
Researchers at Washington University School of Medicine in St. Louis have found that a defect in an enzyme called APT1 interferes with the ability to secrete insulin, contributing to the development of Type 2 diabetes in people who are overweight or obese.
After 40 Years of Decline, Stroke Death Rates Are Rising Again
Millennials face a greater risk of ischemic stroke death than Generation X, according to a Rutgers study.
Potential New Targets Identified in Advanced Non-Alcoholic Fatty Liver Disease
Using the latest technologies—including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells—researchers have uncovered novel candidate drug targets for non-alcoholic fatty liver disease (NAFLD). The research was led by investigators at the Icahn School of Medicine at Mount Sinai. Utilizing these innovative methods, the investigators discovered a network of cell-to-cell communication driving scarring as liver disease advances. The findings, published online on January 4 in Science Translational Medicine, could lead to new treatments.
UT Southwestern immunologists uncover obesity-linked trigger to severe form of liver disease
UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure.
MD Anderson Research Highlights for December 19, 2022
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include a cell cycle checkpoint inhibitor with potential therapeutic effects in an ovarian cancer subtype, a telementoring program for French-speaking oncology providers in Africa, insights into the relationship between obesity and immunotherapy side effects, updates to the world’s largest cancer drug discovery knowledgebase, improvements to treatment response by blocking the EGFR pathway, and a novel noninvasive diagnostic test for immunotherapy-related kidney injury.
New Report Details Steps to Reverse Decline in U.S. Life Expectancy
The Bloomberg American Health Initiative at the Johns Hopkins Bloomberg School of Public Health released a report today setting out 10 practical steps to address major causes of declining life expectancy in the U.S.
Exercise during Pregnancy Offsets Risks to Fetus from Maternal Obesity
Article title: Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism Authors: Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu From the authors: “These findings suggest that [maternal…
Positively Charged Nanomaterials Treat Obesity Anywhere You Want
Columbia researchers invent new method to treat obesity by using cationic nanomaterials that can target specific areas of fat and inhibit the unhealthy storage of enlarged fat cells. “Our studies highlight an unexpected strategy to treat visceral adiposity and suggest a new direction of exploring cationic nanomaterials for treating metabolic diseases,” said Columbia Engineering’s Biomedical Engineering Prof Kam Leong, a pioneer in using polycation to scavenge pathogens.
Believe it or ‘nut’, almonds can help you cut calories
Weight loss is never an easy nut to crack, but a handful of almonds could keep extra kilos at bay according to new research from the University of South Australia.