Uncovering Novel Genomes from Earth’s Microbiomes

Reported in Nature Biotechnology, the known diversity of bacteria and archaea has been expanded by 44% through a publicly available collection of more than 52,000 microbial genomes from environmental samples resulting from a JGI-led collaboration involving more than 200 scientists around the world.

What’s That Growing on Your Face Mask?

Many people reuse masks and other face coverings many times without sanitizing them. That is likely because current sanitization methods can be cumbersome. A new device using a hanging rack and UV-C light can sterilize up to six masks and other items simultaneously and quickly, killing bacteria, yeasts, mold spores, and viruses. This device has shown its efficacy against pathogens including the highly-contagious E-coli, which was eradicated in about one minute.

How Did Red Algae Survive in Extreme Environments?

Red algae have persisted in hot springs and surrounding rocks for about 1 billion years. Now, a Rutgers-led team will investigate why these single-celled extremists have thrived in harsh environments – research that could benefit environmental cleanups and the production of biofuels and other products.

Bacteria Can Defuse Dangerous Chemical In Passaic River

Bacteria that can help defuse highly toxic dioxin in sediments in the Passaic River – a Superfund hazardous waste site – could eventually aid cleanup efforts at other dioxin-contaminated sites around the world, according to Rutgers scientists. Their research, published in the journal Environmental Science & Technology, needs further work to realize the full potential of the beneficial bottom-dwelling microbes.

Cleaning up the Germs that Cause COVID-19

A meme is circulating on the Internet comparing the statement “once COVID-19 is over” to the wishful possibility of winning the lottery. Both might seem very out of reach, but continuing to remain vigilant with frequent handwashing, social distancing, mask-wearing,…

Harmful Microbes Found on Sewer Pipe Walls

Can antibiotic-resistant bacteria escape from sewers into waterways and cause a disease outbreak? A new Rutgers study, published in the journal Environmental Science: Water Research & Technology, examined the microbe-laden “biofilms” that cling to sewer walls, and even built a simulated sewer to study the germs that survive within.

Dangerous Tick-Borne Bacterium Extremely Rare in New Jersey

There’s some good news in New Jersey about a potentially deadly tick-borne bacterium. Rutgers researchers examined more than 3,000 ticks in the Garden State and found only one carrying Rickettsia rickettsii, the bacterium that causes Rocky Mountain spotted fever. But cases of tick-borne spotted fevers have increased east of the Mississippi River, and more research is needed to understand why, according to a study in the American Journal of Tropical Medicine and Hygiene.

Next-gen nano technologies to tackle infection and diagnose disease

Next-gen nano technologies that can prevent infection and diagnose disease are set to transform the medical industry as this important UniSA research is awarded more than $2 million dollars under the National Health and Medical Research Council (NHMRC) 2021 Investigator Grants.

Supercomputing Aids Scientists Seeking Therapies for Deadly Bacterial Disease

A team of scientists led by Abhishek Singharoy at Arizona State University used the Summit supercomputer at the Oak Ridge Leadership Computing Facility to simulate the structure of a possible drug target for the bacterium that causes rabbit fever.

Algae in the Oceans Often Steal Genes from Bacteria

Algae in the oceans often steal genes from bacteria to gain beneficial attributes, such as the ability to tolerate stressful environments or break down carbohydrates for food, according to a Rutgers co-authored study.
The study of 23 species of brown and golden-brown algae, published in the journal Science Advances, shows for the first time that gene acquisition had a significant impact on the evolution of a massive and ancient group of algae and protists (mostly one-celled organisms including protozoa) that help form the base of oceanic food webs.

Bacteria potentially involved in the development of type 2 diabetes

blood and tissue samples from 40 patients suffering from severe obesity taken during bariatric surgery were used. Half of the participants suffered from type 2 diabetes, while the other subjects showed insulin resistance without being diabetic.

The researchers identified the bacterial genetic material in each of the tissues sampled, which came from the liver and three abdominal fat deposits. Based on the type of bacteria present and their relative abundance, the researchers were able to determine the bacterial signature for each tissue.

Designer Probiotic Treatment for Cancer Immunotherapy

Columbia Engineers have engineered probiotics to safely deliver immunotherapies within tumors, including nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. Continuously released by bacteria, the drugs continue to attack the tumor after just one dose, facilitating an immune response resulting in tumor regression. The versatile probiotic platform can also be used to deliver multiple immunotherapies simultaneously, enabling the release of effective therapeutic combinations within the tumor for more difficult-to-treat cancers like colorectal cancer.

Study: Diet Makes a Difference in Fight Against Hospital-Acquired Infection

Popular diets low in carbs and high in fat and protein might be good for the waistline, but a new UNLV study shows that just the opposite may help to alleviate the hospital-acquired infection Clostridioides difficile. The results appeared in a study published Feb. 11 in mSystems, an open access journal of the American Society for Microbiology.

New Portable Tool Analyzes Microbes in the Environment

Imagine a device that could swiftly analyze microbes in oceans and other aquatic environments, revealing the health of these organisms – too tiny to be seen by the naked eye – and their response to threats to their ecosystems. Rutgers researchers have created just such a tool, a portable device that could be used to assess microbes, screen for antibiotic-resistant bacteria and analyze algae that live in coral reefs. Their work is published in the journal Scientific Reports.

‘Are Noncommunicable Diseases Communicable?’ Rutgers Experts Available to Discuss Paper in Science Today

New Brunswick, N.J. (Jan. 16, 2020) – Rutgers professors Maria Gloria Dominguez-Bello and Martin J. Blaser are available to discuss a paper in the journal Science today on whether diseases long thought to be noncommunicable – such as cardiovascular diseases, cancer…

Delivering TB Vaccine Intravenously Dramatically Improves Potency, Study Shows

Worldwide, more people die from tuberculosis than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn’t that reliable. But a new Nature study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.

Trial Suggests Babies in Intensive Care Can be Better Protected From Parental Bacteria

For sick or prematurely born babies spending their first days of life in a hospital’s neonatal intensive care unit (NICU), the soothing voice and gentle touch of a loving parent can have a tremendous impact toward a positive outcome — that is, unless mom or dad’s visit leaves the infant with something extra: a dangerous bacterial infection.

Why It Matters: Prescription for Disaster

Bacteria are becoming increasingly resistant to antibiotics. A major cause is their overuse in both humans and animals. At the same time, a lack of financial incentives is setting back efforts to discover new classes of antibiotics. The problem is both global and local, and without new initiatives, many common medical conditions could become deadly once again.

Many cooks don’t spoil the broth: Manifold symbionts prepare their host for any eventuality

Deep-sea mussels, which rely on cooperative symbiotic bacteria for their food, harbor a surprisingly high diversity of these bacterial “cooks”: Up to 16 different bacterial strains live together in the mussel’s gills, each with its own abilities and strengths. Thanks to this diversity of symbiotic bacterial partners, the mussel is prepared for all eventualities. The mussel bundles up an all-round carefree package, a German-Austrian research team including Jillian Petersen from the University of Vienna and Rebecca Ansorge and Nicole Dubilier from the Max-Planck-Institute for Marine Microbiology now reports in Nature Microbiology.

Scientists Discover New Antibiotic in Tropical Forest

Scientists from Rutgers University and around the world have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a “plant probiotic,” more robust plants and other antibiotics. Probiotics, which provide friendlier bacteria and health benefits for humans, can also be beneficial to plants, keeping them healthy and more robust. The new antibiotic, known as phazolicin, prevents harmful bacteria from getting into the root systems of bean plants, according to a Rutgers co-authored study in the journal Nature Communications.

High Levels of Fecal Bacteria Found in Lower Raritan River

New Brunswick, N.J. (Sept. 17, 2019) – High levels of fecal bacteria have often been found at six new water sampling sites in the lower Raritan River since May, according to a Rutgers-coordinated monitoring program that included more than 20…