news, journals and articles from all over the world.
Among 88,183 U.S. high school students, marijuana use declined from 23.1% in 2011 to 15.8% in 2021, with first-time use before age 13 dropping from 8.1% to 4.9%. In 2021, use was highest among 12th graders (22.4%) and 11th graders (18.7%). Notably, girls (17.8%) surpassed boys (13.6%) in reported use in 2021, reversing past trends. While Asian, Hispanic, and white adolescents saw declines, Black adolescents had a higher usage rate of 20.5% in 2021, indicating ongoing racial disparities.
For people with ischemic stroke, treatment with the clot-busting drug tenecteplase is associated with a slightly higher likelihood of an excellent recovery and reduced disability three months later than the drug alteplase, according to a meta-analysis published in the October 16, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that the likelihood of good recovery was similar between the two treatments.
Injured adolescents from marginalized groups treated at pediatric trauma centers are more likely to be tested for drugs and alcohol than white adolescents, even when accounting for injury severity.
People with chronic diabetic foot ulcers could soon have a new way to treat their wounds for faster healing and fewer hospital stays. Researchers from Michigan State University and South Shore Hospital have uncovered that the combination of two common diabetes drugs — injectable insulin and orally-administered metformin — increases the amount of metformin at the wound site.
Researchers analyzed data from 241 Florida law enforcement agencies across 67 counties to explore police misconduct. They uncovered 24 types of offenses, such as assault, weapons violations, manslaughter, and perjury. Notably, failure to report and perjury topped the list, with sexual crimes and drug/alcohol-related offenses also prominent.
Drug-involved infant deaths more than doubled (120% increase) from 2018 to 2022, with the greatest proportion of deaths in 2021 (25.8%). The most prevalent underlying causes of death included assault (homicide) by drugs, medicaments and biological substances (35.6%).
During pregnancy, the effects of therapeutical doses of amphetamine have been investigated on birth outcomes in humans. However, a thorough investigation of the mechanisms underlying the long-term effects of embryonal exposure to addictive doses of amphetamine remains largely unexplored.
World first research from the University of South Australia shows that antipsychotics can be reformulated with a strategically engineered coating that not only mitigates unwanted weight gain but also boosts serotonin levels by more than 250%.
Using his platform composed of carbon nanotubes and gold nanoparticles, Professor Alexander Star added antibodies to detect the opioid. His sensor can also distinguish fentanyl from several other common opioids.
People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.
Washington University’s Jianjun Guan to create custom nanoparticles to fight inflammation, fibrosis.
As authorities crack down on illicit drugs, University of South Australia experts have issued an alert on the use of the synthetic stimulant pentylone, as new research finds a 75% increase in detections across Australia.
RUDN University doctors demonstrated the capabilities of a new method for remote analysis of drugs in packaging and after entering the body. They can be assessed using radio thermal emission of nanoparticles in drugs. Scientists were able to check the suitability of the medicine without opening the packaging or monitor it inside the body.
Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.
Scientists have long thought of the fluid-filled sac around our lungs merely as a cushion from external damage.
FragDPI, a novel drug-protein interaction prediction method, outperforms baselines and identifies specific interaction parts, aiding drug discovery
This cutting-edge technique activates a specific neurotransmitter receptor using mid-infrared light, which can penetrate deep into tissue and offers unparalleled pharmacological and spatiotemporal precision in three dimensions.
ACP leaders have strong words for pharmaceutical and other health care companies that are challenging the implementation of the Medicare prescription drug price negotiation program. So far, these businesses have spent approximately $400 million challenging the program in U.S. courts. ACP, along with other medical societies, is pushing back.
Although people with opioid use disorder (OUD) are significantly more likely to overdose or have a complication after major surgery than those without the disorder, using medications for the treatment of OUD before surgery may eliminate that extra risk, suggests a large, first-of-its-kind study presented at the ANESTHESIOLOGY® 2023 annual meeting.
Some people may be physically unable to use the current evidential breath analysis machines, relied upon by police to gather proof of driving under the influence of alcohol or drugs, new research from the University of Sheffield indicates.
Investigators at Mount Sinai Find Strong Association of Kidney Injury with Dasatinib, a Commonly Used Oncological Therapeutic Findings suggest an update may be warranted for current clinical care, screening guidelines, and FDA guidance on adverse events Principal Investigator: Evren U.…
New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer’s disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes.
Nanovesicles can be bioengineered to target cancer cells and deliver treatments directly, according to research at Binghamton University, State University of New York.
Digital Science is positioning itself to play an even greater role in the pharmaceutical industry’s all-important drug discovery, by helping industry sift through a sea of information and focus on the research that matters.
The spread of drug-resistant microbes has become a global health concern that threatens our ability to treat infections. The widespread use of antimicrobials in livestock, such as swine farms, exacerbates this problem.
Narcan, a prescription nasal spray that reverses opioid overdoses, can now be sold over the counter after the FDA authorized the move on March 29. Peter A. Clark, S.J., PhD, is the director of the Institute of Bioethics and professor…
What: According to a recent Washington Post article, prescriptions for Adderall rose more than 30% over the past five years and accelerated during the pandemic. Now, there is a nationwide shortage of the drug. Nearly 40% of all prescriptions for stimulants, including…
People with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagnosed type 2 diabetes who took the diabetes drug pioglitazone were less likely to later develop dementia than those who did not take the drug. The study is published in the February 15, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Among people with epilepsy, Black, Latino and Native Hawaiian and Other Pacific Islander people are less likely to be prescribed newer drugs than white people, which can be a marker of the quality of care, according to a study published in the January 11, 2023, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology.
Experts reviewing the use of a commonly prescribed family of drugs, known as fluoroquinolones, say safety warnings differ internationally
Cancer Council SA-funded researcher Associate Professor Stephanie Reuter Lange from UniSA hopes that a simple computer program can help personalise treatment for cancer patients.
Medications should be coupled with physical therapy, exercise programs and treatment of the underlying degenerative disease process and medical illness.
Once a state legalizes recreational cannabis and increase in youth using it illegally occurs, report researchers at University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Science.
UC San Diego study shows suicide rates were higher in pharmacists than in the general population between 2003 and 2018, with job problems being the most significant feature associated with the suicides.
A five-year, $2.59 million grant from the National Institutes of Health will allow a psychology professor at Binghamton University, State University of New York to study the mechanisms of addiction.
Two National Institute of Health (NIH) grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences, is the Principal Investigator on both grants — $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.
Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new University of Bristol-led study. The research, published in Scientific Reports, repeatedly assessed 665 participants in a general population cohort on their tobacco and cannabis use between ages 14 to 29 years, before pregnancy.
William L. “Bill” Greene, PharmD, chief pharmaceutical officer, to receive the 2021 Shelby Rhinehart Public Service Lifetime Achievement Award.
William L. “Bill” Greene, PharmD, chief pharmaceutical officer, to receive the 2021 Shelby Rhinehart Public Service Lifetime Achievement Award.
It’s no secret that studies show that sexually diverse youth – in particular, lesbian, gay and bisexual (LGB) youth – use more cannabis and experience more mental health challenges than their heterosexual peers. But what about the changes that occur…
Individuals who perceived cannabis as both low-risk and available were 22 times more likely to have used cannabis in the past year than those perceiving cannabis as both high-risk and unavailable
The idea that cannabis is a ‘gateway drug’ to more harmful substances such as opioids is controversial, yet has substantially impacted drug policy, education and how we conceptualize substance use. A new systematic review and meta-analysis has found that people…
High-dose buprenorphine therapy, provided under emergency department care, is safe and well tolerated in people with opioid use disorder experiencing opioid withdrawal symptoms, according to a study supported by the National Institutes of Health’s National Institute on Drug Abuse (NIDA)…
Rates of clinical depression, substance use key in predicting neglectful behavior
PULLMAN, Wash. – Even before the pandemic made Zoom ubiquitous, Washington State University researchers were using the video conferencing app to research a type of cannabis that is understudied: the kind people actually use. For the study, published in Scientific…
CU Department of Surgery’s Victoria Huynh, MD, and Sarah Tevis, MD, are developing new protocols to improve surgical recovery
New grant expands Texas tobacco program, targets substance use patients in rural communities
Multi-Disciplinary Approach to Eradicate All Traces of HIV from Body, and Treat Co-existing Substance Use Disorders/Addiction
While autistic individuals are less likely to use substances, those who do so are more likely to self-medicate for their mental health symptoms, according to new research from the University of Cambridge and published today in The Lancet Psychiatry .…
‘Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery’ gives the present status and future perspective of Polymeric nanoparticles, Liposomes, Carbon Nanotubes, Magnetic Nanoparticles, Silica Based nanomaterial, Hydrogels, Metallic Nanoparticles, Cyclodextrins, Poly (Lactide-Co-Glycolide) and its Copolymers. Improvement of a vector for…
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