Former college athletes with a history of concussions were more likely to perceive themselves as cognitively impaired later in life if they had mood disorders such as depression and anxiety – even when testing showed no such decline in mental acuity, a study by UT Southwestern Medical Center researchers has found.
Tag: Clinical Research
UTSW Research: Python guts, emergency room visits, and more
Regeneration insights from snake intestines / Understanding why cancer patients visit the ED / How burr holes affect transcranial direct current stimulation
U-M Rogel Cancer Center names 2 new clinical research leaders
The University of Michigan Rogel Cancer Center has named Kyle Cuneo, M.D., its new associate director for clinical research. In addition, a new position of assistant director for clinical research will be filled by John Magenau, M.D.
Vesalio Announces Clinical Study Initiative for the Recently Launched pVasc Thrombectomy System and Planned Attendance at TCT, VIVA, and VEITH Meetings
Vesalio, a global thrombectomy company dedicated to advancing patient care across all vascular diseases, announces the initiation of a prospective, single-arm, multi-center study supporting the recently launched pVasc™ Thrombectomy System for non-surgically removing peripheral occlusions.
AI tool helps identify heart failure risk in diabetes patients
Researchers at UT Southwestern Medical Center have developed a machine learning model that can identify patients with diabetic cardiomyopathy, a heart condition characterized by abnormal changes in the heart’s structure and function that predisposes them to increased risk of heart failure. The findings, published in the European Journal of Heart Failure, offer a data-driven method to detect a high-risk diabetic cardiomyopathy phenotype, enabling early interventions that could help prevent heart failure in this vulnerable population.
CovarsaDx Welcomes Rich Masino as Senior Director of Strategic Partnerships and Business Development
CovarsaDx, a clinical research organization at the forefront of in vitro diagnostics (IVD) and medical device trials, has appointed Rich Masino as senior director of strategic partnerships and business development. Bringing over 30 years of experience in biotech, pharma, and medical device diagnostics, Masino will focus on driving growth and forging strategic partnerships across CovarsaDx and ZoaDx, while reporting directly to the company’s chief executive officer (CEO).
UTSW study explores link between high school IQ and alcohol use
A person’s IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism. Participants with higher IQ levels were significantly more likely to be moderate or heavy drinkers, as opposed to abstaining.
Johns Hopkins Medicine Study Finds Commonly Used Arm Positions Can Substantially Overestimate Blood Pressure Readings
Investigators say failing to follow arm support guidelines during BP screening could have significant clinical impact
Widespread disparities exist in treating advanced cancers
A study led by researchers at UT Southwestern Medical Center reveals significant disparities across the country in the use of immunotherapy for patients with advanced kidney and bladder cancers.
UNM Cancer Center Opens Ovarian Cancer Clinical Trial Using HIPEC Surgery
The University of New Mexico Comprehensive Cancer Center has opened a clinical trial that applies hyperthermic intraperitoneal chemotherapy (HIPEC) — a proven surgical technique that is used in digestive system cancers — to ovarian cancer.
Children’s Research Institute at UT Southwestern scientists discover kidney cancers rely on mitochondrial metabolism to metastasize
Contrary to how tumors operate while still in the kidney, metastatic kidney cancers rely heavily on mitochondrial metabolism, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Nature.
Natural grass may pose greater risk for football concussions
Young football players who sustained a head-to-ground concussion practicing or playing games on natural grass experienced more symptoms – and significantly higher severity – than those who suffered concussions on artificial turf, researchers at UT Southwestern Medical Center found.
Education level, social media skills linked to cancer fatalism
More educated people who are skilled at finding reliable information through social media don’t always see cancer as fatal while those with less schooling and social media awareness hold more fatalistic beliefs about the disease, researchers at UT Southwestern Medical Center found.
Study identifies 18 proteins linked to heart failure, frailty
An analysis of blood samples from thousands of study participants, led by researchers at UT Southwestern Medical Center, revealed 18 proteins associated with both heart failure and frailty, conditions that commonly develop in late life.
Valentin Fuster, MD, PhD, Received 2024 Distinguished Award From European Society for Clinical Investigation (ESCI)
President of Mount Sinai Fuster Heart Hospital given top honor for his scientific excellence and successful global education initiatives on cardiovascular disease
In psychedelic therapy, clinician-patient bond may matter most
Drug effects have dominated the national conversation about psychedelics for medical treatment, but a new study suggests that when it comes to reducing depression with psychedelic-assisted therapy, what matters most is a strong relationship between the therapist and study participant.
Tip Sheet: Weight loss drugs and cancer prevention, Fred Hutch at AACR, lymphedema Q&A — and new vice president and chief nursing officer
SEATTLE — April 3, 2024 — Below are summaries of recent Fred Hutchinson Cancer Center research findings, patient stories and other news. If you’re covering the American Association for Cancer Research (AACR) Annual Meeting, please see our list of and contact to set up interviews.
Exploring the Impact of Pancreatic Enzyme Therapy in Pediatric Pancreatitis: A Leap Toward Personalized Medicine
A research study recently published in the American Journal of Gastroenterology explains the role of pancreatic enzyme therapy (PERT) in reducing the frequency of acute pancreatitis (AP) in children suffering from acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP).
Launch of a pioneering translational research programme in Europe
– The TRIP initiative establishes three new joint laboratories that bring together fundamental biomedical research and clinical research with the aim of accelerating the delivery of results to patients.
– TRIP will focus on emerging fields such as immuno-oncology, inflammation, and cellular senescence.
Hackensack Meridian Neuroscience Institute Leading The Way In Comprehensive Multiple Sclerosis Research
Explanation of clinical research for MS Awareness month
Two University Hospitals Physician-Scientists to Receive 2024 Top Ten Clinical Research Achievement Awards from the Clinical Research Forum
Two University Hospitals physician-scientists will receive recognition for their profound contributions to advancing clinical research. UH is the only hospital system to have two honorees acknowledged this year by the Clinical Research Forum for the 10 most significant clinical advancements impacting the health and wellness of humanity.
Prof. Dr. Thanyavee Puthanakit, National Outstanding Researcher in Medical Science, with Clinical Research on the Treatment and Prevention of HIV in Youth
Prof. Dr. Thanyavee expressed her appreciation and honor for receiving the Outstanding Researcher Award.
New strategy for safer CAR T cell therapy in lymphomas
In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.
Promising heart drugs ID’d by cutting-edge combo of machine learning, human learning
University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.
Groundbreaking genome editing tools unlock new possibilities for precision medicine
Traditional genome editing faced limitations in achieving ultimate precision until now. Prof. Buchholz’s team has broken through this barrier by creating what many have sought after: a zinc-finger conditioned recombinase.
A blood test shows MS worsening 1 to 2 years before it happens
Multiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability one to two years later, according to a new study spearheaded by researchers at UC San Francisco.
Incheon National University scientists develop new hydrogels for wound management
By leveraging the power of oxygen, these gelatin patches can act as effective tissue adhesives that accelerate the healing of wounds
Neutralizing antibodies that target resistant bacteria
Antibiotic-resistant bacteria pose a major challenge to healthcare systems worldwide. Due to numerous resistance mechanisms, infections with the pathogen Pseudomonas aeruginosa are particularly feared. Researchers at the German Center for Infection Research (DZIF), the University Hospital Cologne, the Helmholtz Centre for Infection Research in Braunschweig and the University Medical Center Hamburg-Eppendorf have now discovered antibodies that could lead to a highly potent treatment option of acute and chronic infections with P. aeruginosa. The study was published in the prestigious scientific journal Cell.
Contraceptive pill users less likely to report depression – study
New research examined data collected from 6,239 women in the United States
Possible cause of male infertility
Mature spermatozoa are characterized by an head, midpiece and a long tail for locomotion. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Unit “Life & Health” at the University of Bonn have found that a loss of the structural protein ACTL7B blocks spermatogenesis in male mice.
Share Your Research with the Respiratory Disease Community at ATS 2024 in San Diego
The American Thoracic Society is accepting scientific abstracts and case report submissions for presentation at the ATS 2024 International Conference in San Diego, May 17-22. Submissions on all aspects of respiratory disease, critical care medicine and sleep medicine will be considered and are due no later than Wednesday, Nov. 1, 2023, at 5 p.m. ET.
Johns Hopkins Medicine Experts Promote Awareness of Health Care Needs for Dwarfism Community
Johns Hopkins Medicine experts lead the longest-running clinic for people with dwarfism and other skeletal conditions. Started in the late 1950s, the clinic, now called the Kathryn and Alan C.
The Latest in Science and Medical Advancement in Otolaryngology-Head and Neck Surgery to be Presented at AAO-HNSF Annual Meeting
The latest research and advances in otolaryngology-head and neck surgery will be presented in Nashville, Tennessee, during the AAO-HNSF 2023 Annual Meeting & OTO Experience, September 30 – October 4.
Endocrine Society honors endocrinology field’s leaders with 2024 Laureate Awards
The Endocrine Society today announced it has chosen 14 leading endocrinologists as winners of its prestigious 2024 Laureate Awards, the top honors in the field.
Report on Impact of COVID-19 on Clinical Trials Operations Published in NCI Journal
A report summarizing the results of a series of surveys distributed to AACI cancer center members was published in the Journal of the National Cancer Institute (JNCI) Cancer Spectrum.
Historical medicine suggests a new way to use modern treatments
The mixture of honey and vinegar, also known as oxymel, has been used as a medical treatment throughout history and now scientists have established that this combination could have modern applications in the treatment of wounds. New research is the first comprehensive exploration of how the mixture could be applied to modern medicine and improve treatments for infections.
CIHR chooses Digital Science to support discoveries for Canada’s health
Digital Science is pleased to announce that the Canadian Institutes of Health Research (CIHR) has chosen Altmetric and Dimensions from Digital Science’s flagship products to support its belief that research has the power to change lives.
A Simple Antibacterial Treatment Solves a Severe Skin Problem Caused by Radiation Therapy
Acute radiation dermatitis (ARD)—characterized by red, sore, itchy or peeling skin—affects up to 95% of people undergoing radiation treatment for cancer. Severe cases can cause significant swelling and painful skin ulcers that can severely impair quality of life, yet little is known about why this condition occurs and no standardized treatments for preventing severe ARD have been widely adapted.
Boosting the effects of a particular microRNA may benefit patients with cervical cancer
Dysregulation of microRNAs, which are molecules involved in controlling gene expression, can promote tumor formation and progression. A study in The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells.
University Hospitals chosen to participate in a groundbreaking initiative to accelerate uptake of practice-changing evidence in health care
Announcement that the Patient-Centered Outcomes Research Institute (PCORI) tapped University Hospitals (UH) as one of 42 health systems nationwide to carry out a pioneering initiative to accelerate the implementation of practice-changing research results in clinical care to improve patients’ outcomes.
UNC Health Provider Ushers in First FDA-Approved Medication for Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is an allergic condition of the esophagus that is on the rise throughout the United States. Patients with the condition typically have inflammation throughout their esophagus and trouble swallowing food – known as dysphagia.Without proper treatment, the lining of the esophagus becomes fibrous, and the passage becomes so narrowed, or strictured, that food can lodge in the esophagus, requiring medical attention.
Controversial Alzheimer’s drug approval sparks surprising impact
When the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer’s drug in nearly 20 years, it had a surprising impact on attitudes about research into the disease.
Researchers demonstrate in mice a new way to deliver medication to malignant brain tumors
Researchers have demonstrated in mice a new approach for delivering medication across the blood-brain barrier to treat tumors that cause aggressive, lethal brain cancer.
Researchers uncover cellular signature to detect pediatric sleep apnea
Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.
Treating parents’ depression boosts treatment of children’s asthma, UTSW study finds
Curbing depression among caregivers improves control of asthma and lung function in children
Many middle-aged adults wary of taking part in studies of dementia prevention drugs
Drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults. But a new study suggests they’ll need to work harder to find volunteers for their clinical trials.
Four Prospective, Multicenter Studies Support Use of Drug-Coated Balloons Over Bare Metal Stents in Treating Femoropopliteal Lesions
New research published in the Journal of the American College of Cardiology shows the use of drug-coated balloons is an optimal approach compared to bare metal stents in treating femoropopliteal lesions.
FAU Awarded $1 Million NIH Grant for Florida Summer Institute in Biostatistics and Data Science
FAU’s Schmidt College of Medicine received a $1 million grant from the National Institutes of Health to launch the first Florida Summer Institute in Biostatistics and Data Science in the Southeastern United States – and one of only 10 sites across the nation.
National Institutes of Health renews Mayo Clinic’s $48 million Clinical and Translational Science Award
Mayo Clinic announced today that its Center for Clinical and Translational Science has successfully renewed funding for its research grant from the National Institutes of Health National Center for Advancing Translational Sciences for five more years.
Cheryl Sampson Hired to Lead UNM Comprehensive Cancer Center’s Clinical Research Office
Cheryl Sampson has close to 25 years in health care research administration experience at both a university cancer center and in the health system setting. It gives her a unique combination of experience that suits the unique nature of the job in New Mexico.