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UrduWhat makes the vital layer of protective cells around the brain and spinal cord — the blood-brain barrier — more or less permeable has been one of the more mystifying questions in neuroscience.
Tag: Blood Brain Barrier
New study offers clues to how cancer spreads to the brain
To understand the molecular processes that influence how cancer cells pass through the blood-brain barrier, researchers used two microfluidic chips that mapped cancer cell migration to the brain and looked at what was happening in the blood-brain niche.
Researchers demonstrate in mice a new way to deliver medication to malignant brain tumors
Researchers have demonstrated in mice a new approach for delivering medication across the blood-brain barrier to treat tumors that cause aggressive, lethal brain cancer.
Researchers test hybrid, soft/hard nanocarriers to deliver drugs to the brain
Researchers are working to develop nanocarriers that deliver drugs across the blood brain barrier. Successful nanocarriers could lead to treatments for brain disorders including Alzheimer’s disease, Parkinson’s disease, ischemic stroke, epilepsy and seizures.
Researchers Use Two-photon Microscopy, Optical Coherence Tomography to View Age-related Blood-brain Barrier Changes
Article title: Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by two-photon microscopy and optical coherence tomography Authors: Ádám Nyúl-Tóth, Stefano Tarantini, Jordan Delfavero, Feng Yan, Priya Balasubramanian, Andriy Yabluchanskiy, Chetan Ahire, Tamas Kiss, Tamas Csipo, Agnes…
First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease
UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.
PECASE Honoree Elizabeth Nance Highlights the Importance of Collaboration in Nanotechnology
Nanoparticles have been used to treat disease for decades, but scientists are now learning more about how they move through human tissue. PECASE honoree and NIGMS grantee Elizabeth Nance is enlisting minds across different scientific fields to solve the challenge of using nanoparticles to target the right site within the body to increase the effectiveness of treatments for newborn brain injury.