Researchers Use Two-photon Microscopy, Optical Coherence Tomography to View Age-related Blood-brain Barrier Changes

Article title: Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by two-photon microscopy and optical coherence tomography Authors: Ádám Nyúl-Tóth, Stefano Tarantini, Jordan Delfavero, Feng Yan, Priya Balasubramanian, Andriy Yabluchanskiy, Chetan Ahire, Tamas Kiss, Tamas Csipo, Agnes…

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.

PECASE Honoree Elizabeth Nance Highlights the Importance of Collaboration in Nanotechnology

Nanoparticles have been used to treat disease for decades, but scientists are now learning more about how they move through human tissue. PECASE honoree and NIGMS grantee Elizabeth Nance is enlisting minds across different scientific fields to solve the challenge of using nanoparticles to target the right site within the body to increase the effectiveness of treatments for newborn brain injury.