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UrduPatients with diabetic kidney disease can potentially be treated with a new investigational medication that may slow the progress of their illness without harmful side effects to their hearts, according to the results of a global clinical trial announced Friday.
Tag: Diabetes
Type 1 diabetes: Tannic acid encapsulation protects transplanted islets from rejection
Transplanting cadaver pancreatic islets is a promising therapy for Type 1 diabetes, but a reactivated autoimmunity means low graft viability after five years. Research now shows that a protective coating of two biopolymers can delay allograft and autoimmune-mediated rejection in mouse models of T1D.
COVID-19 pandemic drives innovation in diabetes care
The COVID-19 pandemic has jumpstarted innovation in health care delivery and allowed for real-world testing of diabetes care models in unprecedented ways, according to a manuscript published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
University Hospitals Cleveland Medical Center Joins the Cardiometabolic Center Alliance as a Key Strategic Partner and Charter Member
The Cardiometabolic Center Alliance (CMCA), founded by Saint Luke’s Mid America Heart Institute is pleased to announce the addition of University Hospitals Cleveland Medical Center as Key Strategic Partner and Charter Member. As a coalition that seeks to establish Cardiometabolic Centers of Excellence nationwide aimed at transforming the treatment of type 2 diabetes (T2D) and related cardiovascular (CV) and renal comorbidities, the CMCA considers University Hospitals (UH) a large integrated health system based in Cleveland, Ohio a key member of the Alliance.
Mount Sinai Researchers Find That Where People Live Can Impact Their Risk for Common Chronic Conditions Including High Blood Pressure and Depression
The researchers found that a persons’ place of residence substantially influences their risk of uncontrolled chronic disease including high blood pressure and depression
Total deaths recorded during the pandemic far exceed those attributed to COVID-19
For every two deaths attributed to COVID-19 in the U.S., a third American dies as a result of the pandemic, according to new data publishing Oct. 12 in the Journal of the American Medical Association.
Women’s expected longevity linked to age at birth of last child
No one knows for sure how long they will live.
15-Year Trend Persists in Disparate Insulin Pump Use in Children
Insulin pumps are widely used in the management of type 1 diabetes (T1D) and reviews have shown insulin pump therapy to be associated with improved glycemic control, fewer severe hypoglycemia events, and improved quality of life. Yet, non-Hispanic white children (NHW) are more than twice as likely as non-Hispanic Black children (NHB) to use this technology.
Genetic differences in fat shape men and women’s health risks
New findings about body fat help explain the differing health risks men and women face – and set the stage for better, more targeted treatments.
Scott, Warner introduce legislation to increase access for diabetes care
Today, U.S. Senators Tim Scott (R-SC), Mark Warner (D-VA), Kevin Cramer (R-ND), Kyrsten Sinema (D-AZ), Tom Cotton (R-AR), and Tina Smith (D-MN) introduced the PREVENT DIABETES Act. This legislation would increase access to the Medicare Diabetes Prevention Program (MDPP) Expanded Model by allowing CDC-recognized virtual suppliers to participate in the program.
UNH Receives $1.8 Million For Biomolecular Research in Diabetes and Cancer
The University of New Hampshire will receive $1.8 million from the National Institutes of Health (NIH) that will further molecular research to better understand drug interactions at the cellular level and help lead to the development of new targeted drugs to treat wide-spread metabolic, growth, neurological and visual disorders including diabetes and cancer.
HIV drugs could prevent diabetes, study suggests
Patients taking drugs called NRTIs to treat HIV and hepatitis B had a 33% lower risk of developing diabetes.
Cleveland Clinic Study Identifies Weight-Loss Threshold for Cardiovascular and Survival Benefits in Patients with Obesity and Diabetes
A Cleveland Clinic study shows that 5 to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison, about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss. The study is published in the October issue of Annals of Surgery.
Complications from diabetes linked to worse memory, IQ in children
A study led by UC Davis Health researchers uncovered that even one severe episode of diabetic ketoacidosis (DKA) in children newly diagnosed with type 1 diabetes is linked to cognitive problems; and among children with a previous diagnosis, repeated DKA exposure predicted lower cognitive performance after accounting for glycemic control.
Prevent Severe COVID Symptoms With Lifestyle Changes
Obesity is contributing to worse outcomes in people with COVID-19. Dr. Naomi Parrella, medical director of the Rush Center for Weight Loss and Bariatric Surgery, explains how managing your weight can lower your risk for severe COVID symptoms and help you prevent other chronic diseases.
Early birds vs night owls: for diabetics, an early bedtime is best
Early to bed, early to rise…while the old saying promises health, wealth and wisdom, new research confirms part of the adage holds true, as a world first study shows that people who go to bed early are more likely to be in better health and more physically active compared to night owls.
Children Who Take Prescription Steroids at Increased Risk for Diabetes, High Blood Pressure, Blood Clots
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.
Factors Inherent to Obesity Could Increase Vulnerability to COVID-19
DALLAS – Sept. 15, 2020 – Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife. They suggest that drugs used to lower inflammation in the lungs could prove beneficial to obese patients with the disease.
Red hot meat: the wrong recipe for heart disease
From MasterChef to MKR, the world’s best chefs have taught us how to barbeque, grill and panfry a steak to perfection. But while the experts may be seeking that extra flavour, new research from the University of South Australia suggests high-heat caramelization could be bad for our health.
Risk factors for mortality in diabetic patients discharged from hospital identified
Patients with diabetes are at a higher risk of mortality when discharged from hospital
Fat Tissue Inflammation Directly Linked to Obesity-Induced Insulin Resistance
Adipose (fat) tissue inflammation is directly linked to obesity-induced insulin resistance, while gut imbalance and mitochondrial dysfunction are not required. These are the findings of new research published in Function, the latest addition to the American Physiological Society’s collection of…
Microgel Immuno-acceptance Method Could Improve Pancreatic Islet Transplant Success
Researchers at the Georgia Institute of Technology and University of Missouri developed a new microgel drug delivery method that could extend the effectiveness of pancreatic islet transplantations — from several years to possibly the entire lifespan of a recipient.
Artificial pancreas can prevent dangerously low blood sugar in people with T1D
A new artificial pancreas system can prevent hypoglycemia—episodes of dangerously low blood sugar—during and after heavy exercise in people with type 1 diabetes, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Obesity linked with higher risk for COVID-19 complications
A review of COVID-19 studies reveals a troubling connection between two health crises: coronavirus and obesity.
ADCES releases core competencies for diabetes care and education specialists
Six key domains outline specific sets of knowledge, skills and abilities critical to the role
Breastfeeding’s Legacy May Protect Against Diabetes
DALLAS – Aug. 25, 2020 – Breastfeeding secures delivery of sugar and fat for milk production by changing the insulin sensitivity of organs that supply or demand these nutrients, a new study led by UT Southwestern scientists suggests. The findings, published in this month’s print issue of Diabetes, could explain how different tissues cooperate to start and maintain lactation and offer strategies to help improve breastfeeding success for mothers who have insufficient milk production.
UCI study finds women with diabetes and high levels of coronary artery calcium at greater risk of death than men
A new study finds women with diabetes and significant levels of calcium in their coronary arteries have higher rates of death from cardiovascular disease and all causes than their male counterparts.
New Research Shows Air Pollution Could Play a Role in Development of Cardiometabolic Diseases, Diabetes
Air pollution is the world’s leading environmental risk factor, and causes more than nine million deaths per year. New research published in the Journal of Clinical Investigation shows air pollution may play a role in the development of cardiometabolic diseases, such as diabetes. Importantly, the effects were reversible with cessation of exposure.
Diabetes care and education specialists honored at 2020 virtual conference
ADCES is an interdisciplinary professional membership organization dedicated to improving prediabetes, diabetes and cardiometabolic care through innovative education, management and support. With more than 12,000 professional members including nurses, dietitians, pharmacists and others, ADCES has a vast network of practitioners working to optimize care and reduce complications. ADCES offers an integrated care model that lowers the cost of care, improves experiences and helps its members lead so better outcomes follow. Learn more at DiabetesEducator.org, or visit us on Facebook or LinkedIn (Association of Diabetes Care & Education Specialists), Twitter (@ADCESdiabetes) and Instagram (@ADCESdiabetes).
Pharmacist-Led Clinic Improves Diabetes Outcomes, Lowers Costs
Pharmacist Candis Morello, PharmD, of Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego, discusses her Diabetes Intensive Medical Management (DIMM) “tune up” clinic for complex type 2 diabetes patients – and why this team-based approach is better for patients and more cost effective for health systems and payers.
High Blood Sugar May Worsen COVID-19 Outcomes
Preliminary observations of COVID-19 patients with diabetes inspired an algorithm for glucose monitoring that’s suspected to help combat the virus’ serious complications.
Non-Fasting Blood Test Can Help Screen Youth for Prediabetes and Diabetes
A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life.
Coming of Age: Emerging Health Preference Research Based on Established Scientific Standards
Value in Health, the official journal of ISPOR, announced today the publication of a series of articles focused on recent developments in the field of health preference research.
Researchers discover sex-specific differences in neural mechanisms for glucose regulation
Researchers from Tufts have discovered neural mechanisms in mice specific to females that switch estrogen from playing a protective role in glucose metabolism to a disruptive role. The discovery could provide clues to the increased risk of insulin resistance and diabetes among post-menopausal women.
Youth with Diabetes Who are Involved in the Decision to Start Continuous Glucose Monitoring are More Likely to Continue Using It
In a new study published in Diabetes Care, researchers at Children’s Hospital of Philadelphia (CHOP) have found that youth who are involved with the decision to start CGM are more likely to continue using the monitoring technology more than two months after starting. The findings suggest that children and adolescents who do not have a role in the decision are less likely to be satisfied with the device and use the device consistently.
Wayne State-led team explores link between diabetes, obesity and liver disease
Faculty from Wayne State University’s Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment.
Novel diabetes drug candidate shows promising properties in human islets and mouse models
Researchers have discovered a new drug candidate that offers a major advance to treat diabetes. Tested on human and mouse pancreatic islets, mouse and rat cell cultures and animal models of Type 1 and Type 2 diabetes, the drug significantly improved four detrimental characteristics of diabetes.
The Mount Sinai Hospital Ranked Among Top in the Nation by U.S. News & World Report; Brookdale Department of Geriatrics and Palliative Medicine Claims No. 1 Spot in Specialty Rankings
The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation’s top hospitals for care excellence in U.S. News and World Report, marking the fifth straight year the hospital has been listed among the top 20 in the country while landing on the distinctive “Honor Roll” list.
NIH Awards $9.5 Million for Einstein-Mount Sinai Diabetes Research Center
Albert Einstein College of Medicine has received a $9.5 million, five-year grant from the National Institutes of Health (NIH) to support the Einstein-Mount Sinai Diabetes Research Center (ES-DRC). The multi-institutional center is a leader in basic, translational, clinical, and community-based research and training in type 1 and type 2 diabetes, obesity, and other metabolic disorders.
Insulin Cost-Sharing Caps May Help Kids, Young Adults With Type 1 Diabetes
Although additional policies are needed to relieve insulin’s financial burden, researchers find a national cost-sharing cap helps privately insured children and young adults with type 1 diabetes pay less out-of-pocket.
Gene in Fat Plays Key Role in Insulin Resistance
DALLAS – July 23, 2020 – Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows. The findings, reported in a recent issue of PNAS, could shed light on Type 2 diabetes and other insulin resistance disorders, which remain poorly understood despite decades of study.
As Evidence of “Hormone Disruptor” Chemical Threats Grows, Experts Call for Stricter Regulation
A growing number of chemicals in pesticides, flame retardants, and certain plastics have been linked to widespread health problems including infertility, diabetes, and impaired brain development, a set of reviews of hundreds of studies concludes.
Call to action for stronger, better-funded federal nutrition research
A paper from research, policy, and government experts provides a compelling vision to strengthen existing federal nutrition research and improve cross-governmental coordination in order to accelerate discoveries and improve public health, food security, and population resilience. A coalition of organizations is standing in support of the paper and the need for greater investment and coordination in federal nutrition research.
Gut microbiota provide clues for treating diabetes
The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated.
Study Links Stress Hormone With Higher Blood Sugar In Type 2 Diabetes
A study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine finds a link between the stress hormone cortisol and higher blood sugar levels in people with type 2 diabetes.
COVID-19, telehealth and the hybrid future of diabetes care
Many people with diabetes are wondering if telehealth will become the new norm post pandemic and how the patient experience will evolve. Whitney S. Goldner, MD, Professor of Medicine of the University of Nebraska Medical Center is available to discuss what this new era of…
Philadelphia Tax on Sweetened Drinks Led to Drop in Sales
Philadelphia’s tax on sweetened beverages led to a 38.9 percent drop in the volume of taxed beverages sold at small, independent retailers and a significant increase in the price of taxed beverages, according to new research from the Perelman School of Medicine at the University of Pennsylvania. This study builds on previous research that suggests beverage taxes can help reduce purchases of sugary drinks, led by Christina Roberto, PhD, an associate professor of Medical Ethics and Health Policy at Penn, and senior author on this latest paper published in Health Affairs.
Sorting and secreting insulin by expiration date
The age of insulin parcels may matter, researchers say, when it comes to diagnosing and treating diabetes.
New guidelines for children and adolescents with T2D
A team of paediatric specialists, including an expert from the University of Adelaide, has produced new guidelines regarding assessment and management of type 2 diabetes (T2D) in Australian and New Zealand children and adolescents.
Study Explores Statins’ Role in Insulin Resistance
Article title: Statins activate the NLRP3 inflammasome and impair insulin signalling via p38 and mTOR Authors: Brandyn D. Henriksbo, Akhilesh K. Tamrakar, Jobanjit S. Phulka, Nicole G. Barra, Jonathan D. Schertzer From the authors: “We propose that dysregulated [mammalian target of rapamycin]…