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UrduThe immune system has a biological telecommunications system — small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.
Tag: Immune System
CHOP-led Study Identifies Two Different Regulatory T Cell Populations
A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children’s Hospital of Philadelphia (CHOP). The findings, published today in Science Immunology, could pave the way for new treatments for autoimmune diseases that target the immune system selectively.
Traumatic Brain Injury Interferes with Immune System Cells’ Recycling Process in Brain Cells
In a new study published in the January issue of Autophagy, they found that after traumatic brain injury, the brain’s immune system cells’ internal recycling function slowed dramatically, allowing waste products to build up and interfere with recovery from injury.
20-Year Study May Upend Long-Held Theory About Chromosomes and Cancer
Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.
How a Lowly Immune Cell Helps the Immune System Fight Cancer
New research reveals that long-underestimated neutrophils play key role in determining success of cancer immunotherapy
Artificial Sweetener could dampen immune response to disease in mice
Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.
First nasal monoclonal antibody treatment for COVID-19 shows promise for treating virus, other diseases
A pilot trial by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.
Harvard Medical School Media Immersion: Boston, June 8-9, 2023
Application deadline: March 31
CDI, Axiom Space Sign Agreement to Pursue Science – In Space
Hackensack Meridian science institute, commercial space leader to work together beyond our atmosphere for clues to better protect human health
Chronic Alcohol Use May Increase Risk for SARS-CoV2 Infection, Study Suggests
A newly published animal study found that chronic alcohol consumption may create conditions in the body that can facilitate infection by SARS-CoV2, the virus that causes COVID-19 disease. The study, published in Alcohol: Clinical and Experimental Research, found that chronic alcohol use increased the levels of an enzyme that helps the virus enter the cells and, therefore, may increase the risk for COVID-19.
Immunaeon Joins the RegenMed Hub
Immunaeon is the latest addition to the RegeneratOR’s Innovation AcceleratOR, located in the Regenerative Medicine Hub (RegenMed Hub), a rapidly growing regenerative medicine ecosystem based in the Innovation Quarter of Winston-Salem.
How a high fat diet allows expulsion of intestinal parasite worms
Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.
Why lung cancer doesn’t respond well to immunotherapy
Immunotherapy — drug treatment that stimulates the immune system to attack tumors — works well against some types of cancer, but it has shown mixed success against lung cancer.
Boosting anti-cancer antibodies by reducing their grip
New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (4 February), has shown that changing how tightly an antibody binds to a target could improve treatments for cancer.
Immunocompromised patients remain at higher risk of COVID-19 death in hospital
People with weakened immune systems remain more likely to die if hospitalised with COVID-19 than patients with normal immune systems, a new UK study has confirmed.
More than two billion are infected with this disease; Vitamin D can help
Sarcomas are cancer tumours found in e.g. the bones, muscles or fatty tissue. It is a rare type of cancer seen in only one per cent of cancer patients. It is complex and difficult to treat.
CUVET Successfully Developed the First Stem Cell Transplantation Technology to Treat Pet Diabetes
For the first time in Thailand, a research team from Chula’s Faculty of Veterinary Science (CUVET) is the first to have successfully developed a method to culture dog pancreatic cells from stem cells and cell transplantation technology. They aim to test the method in the lab and sick animals suffering from diabetes.
American Lung Association to Study New Treatment Approach for Lung Cancer
Sean P. Pitroda, MD, Assistant Professor of Radiation and Cellular Oncology at the University of Chicago, has received a Lung Cancer Discovery Award and been selected to join the American Lung Association Research Team for his work to improve treatment response in patients with metastatic non-small-cell lung cancer (mNSCLC).
LJI Instructor Annie Elong Ngono, Ph.D., wins GVN support to advance infectious disease research
LJI Instructor Annie Elong Ngono, Ph.D., has spearheaded important studies into the immune response to deadly pathogens such as dengue virus. Now, this dedication to global health and virology has earned her acceptance to the Global Virus Network’s (GVN) highly selective Rising Star Mentorship Program.
LJI researchers find missing piece of the asthma puzzle
“This is a very striking and significant result that essentially separates LIGHT from any of the other inflammatory cytokines that have been implicated in the process in severe asthmatics.”
Common immune cells can prevent intestinal healing
B cells are critical to the proper functioning of the immune system.
Immune T cell defence is coping with COVID-19 variants of concern – for now
Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.
DNA barcoding reveals cancer cells’ ability to evade the immune system
Some cancer cells can deploy parallel mechanisms to evade the immune system’s defences as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research.
Cecilia Lindestam Arlehamn wins WHAM Edge Award funding to study sex-based differences in Alzheimer’s and Parkinson’s diseases
Cecilia Lindestam Arlehamn, Ph.D., aims to shed light on how sex-based immune system differences may affect the development and progression of these neurodegenerative diseases in men versus women.
Selection of human immune-related genes was driven by the Black Death
New research on ancient DNA found individuals with two copies of a specific variant of the ERAP2 gene were much more likely to survive the plague.
The Black Death shaped the evolution of immunity genes, setting the course for how we respond to disease today, researchers find
An international team of scientists who analyzed centuries-old DNA from victims and survivors of the Black Death pandemic has identified key genetic differences that determined who lived and who died, and how those aspects of our immune systems have continued to evolve since that time.
Disarming the Body’s Defenders
Study shows how certain cancers neutralize T cells to subvert the immune system and help tumors grow
Uncovering the skin’s secrets: Studies show how skin forms differently across the body
Two recent UC Davis studies reveal how skin forms differently across different areas of the body from the face and underarms to the palms of our hands and feet. By profiling the changes in skin, researchers found that the differences have a direct impact for how various skin diseases form across the body.
Newly Discovered “Danger Signal” May Spur Vaccine Development and Allergy Treatment
A team of Rutgers researchers and others inject parasitic worms into mice to study how injured cells trigger an immune response.
Researchers ID Low Immune Cell Responsiveness and High Level of Proteins as Features of COVID-19 Severity
Article title: Chemokines, soluble PD-L1 and immune cell hyporesponsiveness are distinct features of SARS-CoV-2 critical illness Authors: Eric D. Morrell, Pavan K. Bhatraju, Neha A. Sathe, Jonathan Lawson, Linzee Mabrey, Sarah E. Holton, Scott R. Presnell, Alice Wiedeman, Carolina Acosta-Vega,…
The immune system can help us diagnose cancer
One of the deadliest forms of cancer is biliary tract cancer. Only one in three patients diagnosed with the disease is operable. The rest must settle for life-sustaining treatment.
Anti-rejection medication and immunotherapy kicks cancer and protects kidney transplants
Adding immunotherapy to standard anti-rejection medication could change the lives of thousands of kidney transplant patients with incurable cancer, as new research shows it can reduce this risk of organ rejection and eliminate cancer in a quarter of patients.
Milk boost: Research shows how breastfeeding offers immune benefits
When infants breastfeed, they receive an immune boost that helps them fight off infectious diseases, according to recent research from Binghamton University, State University of New York.
Immune system uses two-step verification to defend against HIV
Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system.
Boot Camp for the Immune System
Researchers identify new mechanism that teaches immune cells-in-training to spare the body’s own tissues while attacking pathogens.
Mount Sinai Researchers Learn That ALS May Be Linked to Both the Immune and Central Nervous Systems
New York, NY (June 22, 2022) – The immune system may play a fundamental role along with the central nervous system in amyotrophic lateral sclerosis (ALS), also known as “Lou Gehrig’s disease,” Mount Sinai researchers report. Their study, published…
Nerve Stimulation Promotes Resolution of Inflammation
The nervous system is known to communicate with the immune system and regulate inflammation in the body.
A nanoparticle and inhibitor trigger the immune system, outsmarting brain cancer
Scientists at the University of Michigan fabricated a nanoparticle to deliver an inhibitor to brain tumor in mouse models, where the drug successfully turned on the immune system to eliminate the cancer. The process also triggered immune memory so that a reintroduced tumor was eliminated—a sign that this potential new approach could not only treat brain tumors but prevent or delay recurrences.
Blood Biomarker Predicts Complicated Crohn’s Disease Years Before Diagnosis: Study
An international team led by a University of Toronto researcher has found that an antibody detectable in blood predicts severe Crohn’s disease and is detectable up to seven years prior to disease diagnosis.
Genetic test can diagnose certain immune system disorders
Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections.
Researchers Identify Potential Target for Treating Autoimmune Diseases
New research using a mouse model for multiple sclerosis has uncovered a potential new area to explore for possible treatments for autoimmune disorders.
Type-I interferon stops immune system ‘going rogue’ during viral infections
McMaster University researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from ‘going rogue’ and attacking the body’s own organs.
Discovery of cell protein that keeps Kaposi’s sarcoma herpesvirus dormant
A study led by UC Davis Cancer Center identified a binding protein in cancer cell’s nucleus, known as CHD4, as a critical agent keeping Kaposi’s sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body’s immune system. CHD4 is linked to cancer cell growth in many types of cancers.
Researchers Explore How Lack of Cadherin-11 Protein Drives Immune Response in Atherosclerosis
Article title: Impaired macrophage trafficking and increased helper T-cell recruitment with loss of cadherin-11 in atherosclerotic immune response Authors: Camryn L. Johnson, Lance Riley, Matthew Bersi, MacRae F. Linton, W. David Merryman From the authors: “The results from this study…
Shape of virus may determine RSV infection outcomes
Using a novel technology, the lab of Michael Vahey at the McKelvey School of Engineering uncovered shape-shifting properties of a common respiratory virus.
Einstein-Developed Treatment Strategy May Lead to HIV Cure
Armed with a novel strategy they developed for bolstering the body’s immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice—offering a path to a functional cure for HIV and other chronic viral infections. Their findings were published today in the Journal of Clinical Investigation.
High Protein, Plant-Based Wagyu Beef Helps Increase Immunity — ASEAN’s Best Food Innovation by Chula Students
The Chula Science students team recently won the “ASEAN Food Innovation Challenge 2021” with the imitation Wagyu beef — “The Marble Booster” made from 100 percent high-protein plants. Low in cholesterol, and seasoned with immunity-boosting herbs, this product is soon to be produced and sold in collaboration with Charoen Pokphand Foods (CPF).
UAMS Research Team Finds Potential Cause of COVID-19 ‘Long-haulers’
A research team has identified a potential cause of long-lasting symptoms experienced by COVID-19 patients, often referred to as long-haulers. The findings were published in the journal, The Public Library of Science ONE (PLOS ONE).
Breast milk of mothers who received COVID-19 vaccine contains antibodies that fight illness
The breast milk of lactating mothers vaccinated against COVID-19 contains a significant supply of antibodies that may help protect nursing infants from the illness, according to new research from the University of Florida.
Increasing The Immune System’s Appetite For Cancer Protectors
A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, could leaA two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, could lead to new types of cancer immunotherapies.d to new types of cancer immunotherapies.