Chronic Alcohol Use May Increase Risk for SARS-CoV2 Infection, Study Suggests

A newly published animal study found that chronic alcohol consumption may create conditions in the body that can facilitate infection by SARS-CoV2, the virus that causes COVID-19 disease. The study, published in Alcohol: Clinical and Experimental Research, found that chronic alcohol use increased the levels of an enzyme that helps the virus enter the cells and, therefore, may increase the risk for COVID-19.

Heavy-drinking Rodents Enhance Understanding of Problematic Alcohol Use Patterns

New study findings in mice suggest that repeated binge drinking increases the motivation to consume alcohol to excess. In humans, the pattern of drinking (as well as quantity consumed) can be an important indicator of future drink problems; in adolescents, for example, a binge-drinking pattern can predict development of alcohol use disorder (AUD). Studies using laboratory animals that have been selectively bred to drink alcohol (ethanol) in large amounts can provide valuable insights on problematic drinking patterns, using experimental approaches that would be impossible or unethical to apply in humans. Indeed, many important findings on responses to alcohol have been gained from animal studies, conducted to strict welfare guidelines. The latest study, reported in Alcoholism: Clinical and Experimental Research, examined two behaviors in mice that reflect their motivation to experience alcohol’s rewarding effects on the brain.