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UrduA new study from the University of Delaware will look at Alzheimer’s disease (AD) and examine how changes in arterial stiffness and brain tissue in midlife adults could contribute to cognitive decline. The study aims to pinpoint early risk factors and explore preventive interventions.
Tag: Aging
Grandparents help grandkids in many ways – but the reverse may be true too, poll suggests
A new poll looks at how grandparents are involved in their grandchildren’s lives, and how this relates to mental health and lonelines.
Prolonged sitting can sabotage health, even if you’re young and active
A new study of 1,000 adults found that meeting minimum physical activity guidelines isn’t enough to counteract the health hazards of prolonged sitting.
New Computational Method Links One Mammal’s Striking Longevity and Resistance to Cancer With ‘Dark Genome’
The Roswell Park team has developed a new method to measure mutation loads across species, revealing the role of the “dark genome” — ancient, virus-like genes that affect cellular function. The findings support further exploration of antiviral drugs as potential tools to target the dark genome in controlling cancer.
Can small bursts of activity throughout the day decrease chronic pain?
Setting out to prove that movement indeed is medicine for older adults with chronic knee and hip pain, Wake Forest University researchers have received a $5.7 grant from the National Institutes of Health (NIH) to conduct a five-year study.
Could Poor Sleep in Middle Age Speed Up Brain Aging?
People in early middle age who have poor sleep quality, including having difficulty falling or staying asleep, have more signs of poor brain health in late middle age, according to a study published in the October 23, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Estudo da Mayo Clinic: O que ficar em pé em uma perna só pode te dizer
Quanto tempo uma pessoa consegue ficar em pé — em uma perna só — é uma medida mais reveladora do envelhecimento do que mudanças na força ou na marcha, de acordo com uma nova pesquisa da Mayo Clinic. O estudo foi publicado hoje na revista PLOS ONE.
Minority Aging Study Celebrates 20th Anniversary
The Rush Minority Aging Research Study, the longest-running study of aging in Black men and women, celebrated its 20th anniversary by honoring study participants for devoting their time and efforts in helping advance science.
Protein shakeup: Researchers uncover new function of a protein that may unlock age-related illnesses
McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall.
New initiative to fuel neuroscience and aging research
The University of Miami will invest $30 million to enhance research and innovation in basic science and the areas of neuroscience and aging.
Empowering Independence: Smart Home Solutions for Aging in Place
CEDIA highlights how smart home technology can benefit those aging in place. These innovations enhance safety and convenience while also helping older adults maintain independence and stay connected with loved ones.
New Gallup Survey Shows One in Five U.S. Adults are Lonely
A new survey from Gallup shows one in five U.S. adults report feeling lonely daily. According to the survey, this is the highest level in two years. In 2023, the Surgeon General declared a loneliness epidemic in the U.S. While…
Are you aging well?
University of Miami experts in kinesiology, nutrition, and lifelong learning offer tips to live a long, active life.
Study finds common breast cancer treatments may speed aging process
The findings, published in the Journal of the National Cancer Institute, show that markers of cellular aging—such as DNA damage response, cellular senescence, and inflammatory pathways—significantly increased in all breast cancer survivors, regardless of the type of treatment received.
Despite medical advances, life expectancy gains are slowing
After nearly doubling over the 20th century, the rate of increase in life expectancy has slowed considerably in the last three decades, according to a new study led by the University of Illinois Chicago.
The quest for extended youth
Later this month Bar-Ilan University will host an international conference dedicated to the advancement of research, development and education in the field of healthy longevity.
Clinical Trial Shows Synthetic Cannabis Reduces Agitation in Alzheimer’s Disease
In a study led by the Johns Hopkins University School of Medicine and Tufts University School of Medicine, researchers show that a pill form of the drug dronabinol, an FDA-approved synthetic version of marijuana’s main ingredient, THC, reduces agitation in patients with Alzheimer’s by an average of 30%.
The cost of unhealthy aging
With a rapidly aging global population, investing in longevity science can bridge the 10–year gap between lifespan and healthspan. A breakthrough could save trillions in healthcare costs, improving health outcomes and economic resilience for all, writes Dr. Mehmood Khan.
The Trillion-Dollar Quest For Healthier Aging: How Hevolution Foundation Is Reshaping Longevity Research
In a world where global life expectancy is forecasted to increase from 73.6 years in 2022 to 78.1 years by 2050, the focus is shifting from merely extending lifespan to enhancing healthspan – the number of years lived in good health. At the forefront of this paradigm shift is Hevolution Foundation, a non-profit organization based out of Riyadh, Saudi Arabia – with an unprecedented commitment of up to $1 billion annually to revolutionize the field of aging research.
Rutgers, Michigan State Awarded $3.7 Million Grant to Research Long-Term Impact of Structural Racism on Aging, Health, and Well-Being
A group of researchers led by Rutgers University and Michigan State University have launched a study to understand how lifetime exposure to structural racism in communities affects cognitive aging and physical function decline, and frailty.
Kathleen Pottick, Rutgers Professor of Social Work, Named NASW’s “Social Work Pioneer”
Long-time Rutgers professor Kathleen Pottick is receiving one of the highest honors in the field of social work for her decades-long contribution and research, which focuses on delivering more effective mental healthcare services to children and adolescents.
Northwestern receives $32.4 million to study healthy aging
Northwestern University has been awarded $32.4 million over five years from the Hevolution Foundation to study proteostasis — the processes by which cells maintain protein health for good overall health and to prevent diseases of protein misfolding. A key goal is to improve the health people experience as they age, particularly in their final years.
September is Healthy Aging Month, and Beckman researchers are studying how to improve working memory in older adults.
“People often think that the best way to get better at something is to simply practice it over and over again, but robust skill learning is actually supported by variation in practice,” said lead investigator Elizabeth A. L. Stine-Morrow, a Beckman…
Dolphin Serum Protects Blood Vessel Function in Older Mice
Article title: The bottlenose dolphin (Tursiops truncatus): A novel model for studying healthy arterial aging Authors: Yara Bernaldo de Quirós, Sophia A. Mahoney, Nicholas S. VanDongen, Nathan T. Greenberg, Ravinandan Venkatasubramanian, Pedro Saavedra, Gregory Bossart, Vienna E. Brunt, Zachary S. Clayton, Antonio…
Older Women Are at Greater Risk of Heat Stress Than Older Men
Article title: Sex differences in heat stress vulnerability among middle-aged and older adults (PSU HEAT project) Authors: Olivia K. Leach, Rachel M. Cottle, Kat G. Fisher, S. Tony Wolf, W. Larry Kenney From the authors: “Our data confirm that women…
Novel Study Reveals How Aging Immune System Fuels Cancer Growth, Potentially Opening New Avenues for Prevention
A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults.
Tip Sheet: 20 years since EGFR discovery, aging and immune function, and immunotherapy leader Dr. Lawrence Fong joins Fred Hutch
Below are summaries of recent Fred Hutch Cancer Center research findings, patient stories and other news.
Registration open for 14th annual Markesbery Symposium on Aging and Dementia at the University of Kentucky
The 14th annual Markesbery Symposium on Aging and Dementia is set for Sept. 27-28. The symposium, hosted by UK’s Sanders-Brown Center on Aging, is named in honor and memory of the late William R. Markesbery, M.D., the founding director of Sanders-Brown.
Declining senses can impact mental health and loneliness in aging adults
UChicago researchers found that people who develop sensory disabilities with age tend to have worse mental health, and that different types of sensory disability are associated with different aspects of mental health.
Growth from Adversity: How Older Adults Bounced Back from COVID-19 Pandemic
The study highlights the remarkable resilience of older adults (median age 86) during the COVID-19 pandemic. Disruptions to their routines led many to discover new hobbies like gardening and painting and explore virtual activities such as online yoga.
Beyond the Genome: Project to Map DNA Modifications and Gene Activity Across Lifespan, Generations
Long-term, heritable changes in gene activity fundamentally shape our biology, trigger many of our diseases, and set the clock on how we age. Now, a team of U of U Health scientists is starting an ambitious project to map these changes across the entire human genome.
Alcohol Use in Older Adults Doubles Risk of Brain Bleeds from Falls
Little is known about the association between the frequency of alcohol use and the severity of injuries sustained after a fall in older adults. A study of 3,128 older adults who underwent an initial head CT scan in the emergency department after head trauma from a fall shows that occasional alcohol use was associated with double the odds of a brain bleed when compared to patients with no alcohol use. Daily alcohol use was associated with 150% increased odds of a brain bleed.
Expert Available: Does Your Morning Java Protect Against Dementia?
A new study suggests drinking two or more cups of coffee per day was associated with a nearly 30% decreased risk of dementia over a 7-year period. Moderate tea drinking was also associated with a… …
Menopause is having a moment: Debunking common myths
Many women approach menopause with anxiety about the future. You’ve probably heard about it being a stressful time full of hot flashes, weight gain, and plummeting sex drive. The good news? Menopause is having a moment. That means heightened awareness, more resources dedicated to improving women’s health, and open discussions to ensure you get the information you need.
Aging-related genomic culprit found in Alzheimer’s disease
Researchers at Washington University School of Medicine in St. Louis have developed a way to study aged neurons in the lab without a brain biopsy, allowing them to accurately model the effects of aging in the development of late-onset Alzheimer’s disease.
Study identifies 18 proteins linked to heart failure, frailty
An analysis of blood samples from thousands of study participants, led by researchers at UT Southwestern Medical Center, revealed 18 proteins associated with both heart failure and frailty, conditions that commonly develop in late life.
Exercise More, Sit Less to Manage Frailty and Hypertension Risk in Aging
A new study of middle-age and older adults looks at sex differences in frailty levels and their link with heart health. The findings suggest that moving your body more through regular exercise and sitting less can help keep both heart disease and frailty at bay as we age.
Narcissism decreases with age, study finds
People tend to become less narcissistic as they age from childhood through older adulthood, according to a study published by the American Psychological Association. However, differences among individuals remain stable over time — people who are more narcissistic than their peers as children tend to remain that way as adults, the study found.
An unequal toll of financial stress: Poll of older adults shows different impacts related to health and age
Inflation rates may have cooled off recently, but a new poll shows many older adults are experiencing financial stress – especially those who say they’re in fair or poor physical health or mental health, as well as women and those age 50 to 64. A sizable minority report issues with health care costs.
Older adults with insomnia at greater risk for developing depression
‘Older people who have insomnia show a very exaggerated risk of becoming depressed’
Take summer heat health risks seriously, UTSW experts caution
The scorching heat can be inescapable this time of year, and as temperatures hover around triple digits, experts at UT Southwestern Medical Center caution that uncomfortable weather can escalate to dangerous health conditions.
What You Eat at Age 40 Could Influence Your Quality of Life at 70
A new study found that fewer than 1 in 10 people were able to live free of disease and maintain good physical, cognitive and mental health to age 70 and beyond. The study suggests that sticking to a healthy diet in midlife could increase your chance of achieving healthy aging.
Drugs that kill “zombie” cells may benefit some older women, but not all, Mayo Clinic study finds
Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a “one-size-fits-all” remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a high number of senescent cells, according to findings publishing July 2 in Nature Medicine.
Want to Stay Mentally Sharp Longer? Eat a Healthy Diet Now
Eating a high-quality diet in youth and middle age could help keep your brain functioning well in your senior years, according to new preliminary findings from a study that used data collected from over 3,000 people followed for nearly seven decades.
Daily Sauna Time Might Help Prevent Menopause-Related Weight Gain
New research performed with mice suggests that daily time in a warm environment such as a sauna might help older adults, especially women, combat age-related obesity and insulin resistance. The study shows the potential of heat treatments as a simple way to promote healthier aging.
Intake of Ultra-Processed Foods Linked with Increased Risk of Death
In a new study, older adults who reported consuming higher amounts of ultra-processed foods, as defined by the NOVA classification system, were about 10% more likely to die over a median follow-up of 23 years compared with those who consumed less processed food.
Pilot Study Provides ‘Blueprint’ for Evaluating Diet’s Effect on Brain Health
Researchers from Johns Hopkins Medicine and the National Institutes of Health’s National Institute on Aging say their study of 40 older adults with obesity and insulin resistance who were randomly assigned to either an intermittent fasting diet or a standard healthy diet approved by the U.S. Department of Agriculture (USDA) offers important clues about the potential benefits of both eating plans on brain health.
NUTRITION 2024 Press Materials Available Now
Press materials are now available for NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition (ASN). Top nutrition scientists and practitioners from around the world will gather to share the latest research findings on food and nutrition during the meeting in Chicago from June 29–July 2.
Activating molecular target reverses multiple hallmarks of aging
Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are confirmed in clinical studies, there may be therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease and cancer.
Removal of Ovaries Before Menopause Associated With Reduced White Matter in Brain
Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life.