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UrduBe among the first to hear breaking news in food and nutrition science at NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition held June 29–July 2 at McCormick Place in Chicago.
Tag: Alzheimer’s Disease
Researchers Wrestle with Accuracy of AI Technology Used to Create New Drug Candidates
Researchers at the UNC School of Medicine, UCSF, Stanford, and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.
‘MUSIC map’ reveals some brain cells age faster and are more prevalent in Alzheimer’s
Engineers at the University of California San Diego have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex.
Uniformed Services University Contributes to Groundbreaking Global Study on Multiple System Atrophy
In a groundbreaking study published May 2, 2024 in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder.
FAU Researchers Receive $1M in FDOH Grants to Fight Alzheimer’s Disease
With this funding, FAU researchers will shed light on the biological functions of Alzheimer’s disease (AD) by taking advantage of synthetic chemistry strategies; provide an innovative online screening tool for older drivers with cognitive decline; and gain a deeper understanding of the role of brain cholesterol in AD.
NeuroTherapia Receives Grant from Alzheimer’s Association for Development of First-in-Class Drug for Alzheimer’s Disease
NeuroTherapia, an early-stage clinical pharmaceutical company, announced today that it has received a grant from the Alzheimer’s Association Part the Cloud program for the development of its first-in-class drug, NTRX-07, for the treatment of Alzheimer’s disease (AD).
Belfer family’s $20 million donation invigorates neurodegeneration research at MD Anderson
Laurence Belfer, on behalf of Robert Belfer and the Belfer family, today announced a $20 million gift to The University of Texas MD Anderson Cancer Center to strengthen neurodegeneration research through the Belfer Neurodegeneration Consortium (BNDC), a transformative multi-institutional initiative to advance the study and treatment of Alzheimer’s disease.
Program announced for NUTRITION 2024 to be held June 29–July 2
Reporters are invited to join leading nutrition researchers and professionals at NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition.
Early Alzheimer’s Detection with Artificial Intelligence
“AI-driven neuroimaging techniques have the potential to improve prediction models for Alzheimer’s progression and facilitate personalized treatment strategies,” says Domenico Praticò, MD, the Scott Richards North Star Foundation Chair for Alzheimer’s Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer’s Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM).
Alzheimer’s Drug Development Pipeline: Positive Results, New Insight Position 2024 as ‘Learning Year’
Alzheimer’s treatment studies offer hope as UNLV expert predicts new potential drugs, biomarkers will yield critical insight for future development.
Innovative Microscopy Demystifies Metabolism of Alzheimer’s
Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.
Alzheimer’s disease progresses faster in people with Down syndrome
Nearly everyone with Down syndrome will eventually develop Alzheimer’s disease. Researchers at Washington University School of Medicine in St. Louis have discovered that Alzheimer’s disease starts earlier and moves faster in people with Down syndrome.
Common HIV treatments may aid Alzheimer’s disease patients
Scientists at Sanford Burnham Prebys have now identified promising real-world links between common HIV drugs and a reduced incidence of Alzheimer’s disease. The study, led by Jerold Chun, M.D., Ph.D., was published in Pharmaceuticals.
Young-Onset Dementia Tied to New Risk Factors
“Are the risk factors for early onset Alzheimer’s the same as late onset?” asks Domenico Praticò, MD, the Scott Richards North Star Foundation Chair for Alzheimer’s Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer’s Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM)
Study Suggests Racial Discrimination During Midlife Associated with Alzheimer’s Disease Pathology Later in Life
Racial discrimination experienced during midlife is associated with Alzheimer’s disease pathology, according to a new study from researchers at Wake Forest University School of Medicine and the University of Georgia. The findings appear online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
Key to Unlocking the Secret of Degenerative Brain Disorders Found
A research team led by Dr. Kim Yun Kyung from the Brain Science Institute at the Korea Institute of Science and Technology (KIST), in collaboration with Professor Chang Young-Tae’s team from Pohang University of Science and Technology, has announced the development of a next-generation neuron labeling technology called NeuM.
Immunotherapy for Alzheimer’s disease shows promise in mouse study
Scientists at Washington University School of Medicine in St. Louis have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer’s disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain.
Immune Cells Identified as Key Players in Brain Health
Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer’s and other diseases.
New research at Case Western Reserve University aims to address racial disparities in cognitive decline
According to new research at Case Western Reserve University, connecting with friends is key to limiting social isolation—something researchers believe could also reduce Alzheimer’s, dementia
EXPERT INTERVIEW: Alzheimer’s Association report reveals new Alzheimer’s disease incidence, costs figures and dementia care barriers/challenges
EMBARGOED UNTIL 20 MARCH 2024 On March 20, the Alzheimer’s Association will release its 2024 Alzheimer’s Disease Facts and Figures report, which provides an in-depth look at the latest statistics and information on Alzheimer’s disease prevalence, incidence, mortality, caregiving, dementia care workforce,…
Unlocking Alzheimer’s Mysteries: A Revolutionary Leap in Brain Network Analysis
Dementia stands as one of the most significant global health challenges of the 21st century, with over 50 million individuals worldwide currently affected, a number projected to triple by 2050, reaching 152 million, due to global population aging.
New study reveals breakthrough in understanding brain stimulation therapies
For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior.
“Anti-Choke Mug” – Chula Innovation for Neuro Patients to Drink Water Confidently
Chula Medicine has designed an anti-choke mug with calculated angle, amount, and time of water flow from the mug to the patient’s lips hoping to reduce choking that may lead to lung infection, bring peace of mind to caregivers, and make it safer for patients who will have a better quality of life.
‘Curved’ Walking and a Depth Camera: New Tool Detects Early Cognitive Decline
Gait impairments often are prevalent in the early stages of cognitive decline. Researchers quantitatively compared straight walking and curved walking – a more natural yet complex activity – in healthy older adults and adults with mild cognitive impairment (MCI). A depth camera detected and tracked 25 joints of body movement and signals were processed to extract 50 gait markers. Intriguingly, curved walking illuminated notable disparities between the study groups.
Wrist Device That Monitors Activity Could Help Provide Early Warning of Alzheimer’s
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Doctor discusses a recent study about dementia.
Tresa Mcneal, MD, at Baylor Scott & White Health, discusses a recent study about dementia. What You Need to Know: Dementia affects thinking, memory and social ability. Stroke can cause dementia. Dementia risks increase for those who are sedentary. Reduce…
Study Detects Cognitive Changes in Older Drivers Using In-vehicle Sensors
Continuous, unobtrusive sensors and related monitoring devices are installed in older drivers’ vehicles to detect changes in highly complex activities over time. A driver facing camera, forward facing camera, and telematics unit provide video in real-time to enable researchers to analyze abnormal driving such as getting lost, reaction time and braking patterns as well as travel patterns such as miles driven, miles during the night and daytime, and driving in severe weather. Detecting changes in behavior could generate early warning signs of possible changes in cognition.
Neurons help flush waste out of brain during sleep
Researchers at Washington University School of Medicine in St. Louis have found that brain cell activity during sleep is responsible for propelling fluid into, through and out of the brain, cleaning it of debris.
AI Finds Key Signs That Predict Patient Survival Across Dementia Types
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.
Yoga provides unique cognitive benefits to older women at risk of Alzheimer’s disease, study finds
A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.
Fixing rogue brain cells may hold key to preventing neurodegeneration
A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases.
Drug Repairs Systems That Drain Alzheimer’s-Causing Waste From Brain, Study Shows
Rutgers study led by undergrads and gap-year students breaks ground in the field of neuroscience and suggests experimental medication could treat dementia.
Dementia Researchers Share Recruitment Strategies for Pragmatic Clinical Trial
The Dementia Care (D-CARE) Study (2019-2023), which was conducted at four clinical trial sites in the U.S., compared three approaches in dementia care. Despite challenges during the COVID-19 pandemic, D-CARE successfully enrolled 2,176 racially/ethnically diverse persons with Alzheimer’s disease or related dementias and their caregivers.
UC Irvine-led research team creates novel rabies viral vectors for neural circuit mapping
Irvine, Calif., Feb. 14, 2024 — A research team led by the University of California, Irvine has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer’s disease brain neurons.
Protein Accumulation on Fat Droplets Implicated in Late-Onset Alzheimer’s Disease
In an effort five years in the making, UNC School of Medicine cell biologist Sarah Cohen, PhD, and Rockefeller University’s Ian Windham, PhD, describe the interplay between fats and proteins in brain cells and how their dysfunction contributes to the development of late-onset Alzheimer’s disease.
Better together: Beckman imaging facilities share $3M Alzheimer’s research grant
Beckman researchers and collaborators received $3 million from the U.S. National Institute on Aging to develop diagnostic tools and imaging agents for the early detection of Alzheimer’s disease.
Dr. Claudia Padilla discusses Alzheimer’s and a new treatment.
Claudia Padilla, MD, at Baylor Scott & White Health, discusses Alzheimer’s and a new treatment. What You Need to Know: Alzheimer’s disease is a type of dementia. The most common sign is short-term memory loss. New medication targets the protein…
RNA Scientist Receives Federal Funding to Commercialize Molecular Tool Against Alzheimer’s Disease
University at Albany scientist Scott Tenenbaum, founder of UAlbany spinoff company sxRNA Technologies, Inc. (sxRNA Tech), has received $500,000 from the National Institute on Aging, part of the National Institutes of Health, to study how aging brain cells shape the progression of Alzheimer’s disease, and advance RNA technology that could inform new therapeutics to prevent and treat Alzheimer’s and related dementias.
RUDN chemists suppress overactivity of enzymes that cause Alzheimer’s disease
RUDN University chemists have obtained new azaheterocyclic compounds that inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), regulators of the central nervous system.
Residents of Rural ‘Glades’ Take a ‘Leap of Faith’ to Combat Dementia
Compared to urban dwellers, racially/ethnically diverse older adults face up to an 80 percent greater risk of cognitive impairment in older age, and 2.5 times potentially preventable Alzheimer’s-related (ADRD) hospitalizations.
Re-energizing mitochondria to treat Alzheimer’s disease
Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.
Vaccines May Protect Against Alzheimer’s, But How? Asks Domenico Praticò, MD, FCPP
Commonly used vaccines may also protect against dementia, according to a recent paper published in the Journal of Alzheimer’s Disease [J. Alzheimer’s Disease 2023; 95(2): 703–718)]. The authors found that after receiving the tetanus/diphtheria vaccine and whooping cough (aka, pertussis)…
Hackensack Meridian Health Conducting Research on Alzheimer’s Disease Through Multiple Clinical Trials as Well as Providing Patients with Preventive Care
November is National Alzheimer’s Disease Month Hackensack Meridian Hackensack University Medical Center and the hospital’s Center for Memory Loss and Brain Health are conducting research for Alzheimer’s Disease through four clinical trials with the goal of addressing and improving the…
IU scientists part of NIH-funded national consortium focused on improving Alzheimer’s disease diagnoses
Researchers at Indiana University School of Medicine will play key roles in a national consortium led by Wake Forest University School of Medicine to study the use, interpretation and implementation of biomarkers to diagnose Alzheimer’s disease. The multi-institution effort is funded by a five-year, $9 million grant from the National Institute on Aging, part of the National Institutes of Health, that will establish the Alzheimer’s Diagnosis in Older Adults with Chronic Conditions (ADACC) Network.
New $81M NIH grant will help U.S. answer urgent need for better dementia care
Fueled by new five-year funding expected to total $81 million from the NIH’s National Institute on Aging, a multi-institution team will work to improve understanding of the health care workforce that cares for people with dementia, through surveys and other methods that will produce data for clinicians, researchers, policymakers and others to use.
Rutgers Receives $4.2 Million to Develop Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans
The Resource Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans will work to advance behavioral, social and economic research related to Alzheimer’s disease and other dementias especially in older Asian and Pacific Americans.
Researchers Connect Alzheimer’s-Associated Genetic Variants with Brain Cell Function
Led by scientists at UNC-Chapel Hill and UC-San Francisco, research reveals new non-coding genetic variants associated with Alzheimer’s disease functioning in microglia – brain cells already implicated in the progression of this often-fatal neurodegenerative condition.
World Alzheimer’s Month 2023: Shining a Light on Alzheimer’s – Domenico Praticò
Since 2012, September has been celebrated as World Alzheimer’s Month. Back then, and only eleven years ago, an average of 2 out of 3 people had little understanding of Alzheimer’s disease and associated dementias.
FAU Receives $1.3 Million Grant for Alzheimer’s Outreach in Broward County
The three-year, $1.3 million grant from the Administration for Community Living’s Alzheimer’s Disease Program Initiative will support a groundbreaking project designed to advance health equity and improve quality of life for individuals living with or at high risk for Alzheimer’s disease and related dementias and their family caregivers.
Cholesterol and Inflammation Demonstrate Alzheimer’s Link
A recent study shows that a protein called ABCA7 plays a functional role as a potential biological link between cholesterol and inflammation in Alzheimer’s disease. The new work was published online August 25 in the journal Cells.