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UrduNew findings about body fat help explain the differing health risks men and women face – and set the stage for better, more targeted treatments.
Tag: Obesity
World first study links obesity with reduced brain plasticity
A world-first study has found that severely overweight people are less likely to be able to re-wire their brains and find new neural pathways, a discovery that has significant implications for people recovering from a stroke or brain injury.
Cleveland Clinic Study Identifies Weight-Loss Threshold for Cardiovascular and Survival Benefits in Patients with Obesity and Diabetes
A Cleveland Clinic study shows that 5 to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison, about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss. The study is published in the October issue of Annals of Surgery.
Prevent Severe COVID Symptoms With Lifestyle Changes
Obesity is contributing to worse outcomes in people with COVID-19. Dr. Naomi Parrella, medical director of the Rush Center for Weight Loss and Bariatric Surgery, explains how managing your weight can lower your risk for severe COVID symptoms and help you prevent other chronic diseases.
Factors Inherent to Obesity Could Increase Vulnerability to COVID-19
DALLAS – Sept. 15, 2020 – Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife. They suggest that drugs used to lower inflammation in the lungs could prove beneficial to obese patients with the disease.
Exercise and Insulin Metabolism in NAFLD
The obesity epidemic has led to an increase in the number of people who have a form of liver disease known as nonalcoholic fatty liver disease, or NAFLD. The disease can cause dangerous levels of fat to build up in…
Stress Responder Protein Found to Protect against Metabolic, Gut Changes in Mice
New research in mice suggests a protein found predominately in white blood cells helps keep gastrointestinal bacteria in balance and may protect against metabolic disorders.
Diabetes-in-a-dish model uncovers new insights into the cause of type 2 diabetes
Researchers have developed a novel ‘disease-in-a-dish’ model to study the basic molecular factors that lead to the development of type 2 diabetes, uncovering the potential existence of major signaling defects both inside and outside of the classical insulin signaling cascade, and providing new perspectives on the mechanisms behind insulin resistance in type 2 diabetes and possibly opportunities for the development of novel therapeutics for the disease.
Obesity may alter immune system response to COVID-19
Obesity may cause a hyperactive immune system response to COVID-19 infection that makes it difficult to fight off the virus, according to a new manuscript published in the Endocrine Society’s journal, Endocrinology.
Sulfatase 2 Plays Role in Development of Obesity-induced Fatty Liver Disease
Article title: Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease Authors: Tae Hyo Kim, Bubu A. Banini,* Faizal Z. Asumda, Nellie A. Campbell, Chunling Hu, Catherine D. Moser, Abdirashid…
Fat Tissue Inflammation Directly Linked to Obesity-Induced Insulin Resistance
Adipose (fat) tissue inflammation is directly linked to obesity-induced insulin resistance, while gut imbalance and mitochondrial dysfunction are not required. These are the findings of new research published in Function, the latest addition to the American Physiological Society’s collection of…
Infants in Households With Very Low Food Security May Have Greater Obesity Risk
Infants from households reporting very low “food security,” a measure of access to adequate and healthy meals, tend to weigh more than those from households with relatively high food security.
Transplanted brown-fat-like cells hold promise for obesity and diabetes
A potential therapy for obesity would transplant HUMBLE (human brown-like) fat cells, human white fat cells that have been genetically modified using CRISPR to become similar to heat-generating brown fat cells.
Excessive Fructose Consumption May Cause a Leaky Gut, Leading to Fatty Liver Disease
Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut.
Stomach Capacity, Desire to Eat Increases at Buffets
Research suggests stomach capacity in obesity changes to accommodate different eating situations, which has an effect on feelings of fullness and the urge to overeat. The study is published in the American Journal of Physiology-Gastrointestinal and Liver Physiology.
Major weight loss — whether from surgery or diet — has same metabolic benefits
A longstanding theory has suggested that gastric bypass surgery may have unique, weight loss-independent effects in treating type 2 diabetes. But new research from Washington University School of Medicine in St. Louis indicates that weight loss after surgery, rather than the surgery itself, drives metabolic improvements, such as the remission of diabetes.
Sugar Causes Obesity Even without Sweet Taste
Article title: Sugar causes obesity and metabolic syndrome in mice independently of sweet taste Authors: Ana Andres-Hernando, Masanari Kuwabara, David J. Orlicky, Aurelie Vandenbeuch, Christina Cicerchi, Sue C. Kinnamon, Thomas E. Finger, Richard J. Johnson, Miguel A. Lanaspa From the authors:…
High-fat Diet and Genetics Lead to Anxiety and Depression in Rats
New research in a genetically diverse rat strain finds high-fat diet and genetics together increase anxiety and depression-like behavior in addition to negatively affecting metabolic health. The study is published ahead of print in Physiological Genomics.
Wayne State-led team explores link between diabetes, obesity and liver disease
Faculty from Wayne State University’s Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment.
NIH Awards $9.5 Million for Einstein-Mount Sinai Diabetes Research Center
Albert Einstein College of Medicine has received a $9.5 million, five-year grant from the National Institutes of Health (NIH) to support the Einstein-Mount Sinai Diabetes Research Center (ES-DRC). The multi-institutional center is a leader in basic, translational, clinical, and community-based research and training in type 1 and type 2 diabetes, obesity, and other metabolic disorders.
Double Surgery Improves Chances for Heart Transplant in Patients with Obesity
Pairing bariatric surgery with LVAD heart surgery may be an effective bridge to heart transplant for obese patients.
Study finds weight loss surgery cost disparity
A new study from the University of Georgia finds that users of public insurance are paying more for bariatric weight loss surgery compared to private insurance patients.
Macrophages Play Important Role in Pediatric Obesity-associated Kidney Disease
Article title: Depletion of macrophages slows the early progression of renal injury in obese Dahl salt-sensitive leptin receptor mutant rats Authors: Bibek Poudel, Corbin A. Shields, Andrea K. Brown, Ubong Ekperikpe, Tyler Johnson, Denise C. Cornelius, Jan M. Williams From the…
Ohio State Study: Exercise Increases Benefits Of Breastmilk For Babies
A new study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine finds even moderate exercise during pregnancy increases a compound in breast milk that reduces a baby’s lifelong risks of serious health issues such as diabetes, obesity and heart disease.
2020 Warren Alpert Prize Recognizes Seminal Discoveries in Metabolism
The 2020 Warren Alpert Foundation Prize has been awarded to a trio of researchers for seminal discoveries about the function of key intestinal hormones, their effects on metabolism and the subsequent design of treatments for type 2 diabetes, obesity and short bowel syndrome.
People who eat a late dinner may gain weight
Eating a late dinner may contribute to weight gain and high blood sugar, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Obesity Patients Report Health Challenges During Shelter in Place
Shelter-in-place orders to reduce the spread of COVID-19 put unusual strains on people with obesity, making it more difficult for them to eat properly and manage their weight, according to a UT Southwestern study.
Mexican Immigrant Obesity Rates Climb with Deportation Fears
Stress, unhealthy foods contribute to obesity in undocumented adults and children, Rutgers study reports
Leaders Call for ‘Moonshot’ on Nutrition Research
Leading nutrition and food policy experts outline a bold case for strengthening federal nutrition research in a live interactive session as part of NUTRITION 2020 LIVE ONLINE, a virtual conference hosted by the American Society for Nutrition (ASN).
Study Suggests Low-carbohydrate, High-fat Diet Protects against Obesity
Article title: Dietary carbohydrates modulate metabolic and β-cell adaptation to high-fat diet-induced obesity Authors: Tracy K. Her, William S. Lagakos, Matthew R. Brown, Nathan K. LeBrasseur, Kuntol Rakshit, Aleksey V. Matveyenko From the authors: “These studies support the hypothesis that low carbohydrate/high…
Dieting? Studies Weigh In on Opportunities and Risks
Get the latest research findings on fad diets, losing weight and healthful eating at NUTRITION 2020 LIVE ONLINE, a virtual conference featuring leading nutrition experts from around the world.
Expert on how to keep motivated and maintain weight during COVID-19
When it comes to weight gain, Professor Riebe notes, “Weight and weight gain is very complex, but to simplify, it really boils down to energy in, energy out, or what you’re taking in as food, and your physical activity. So,…
Expert offering guidance on the minimum daily dose of physical activity during COVID-19
In discussing how much and what types of physical activity are recommended according to national guidelines, Professor Riebe notes, “There are national guidelines for physical activity and there are guidelines both for cardiorespiratory activity and also for resistive activity. So,…
Lack of physical activity during COVID-19 may fuel childhood obesity, new study finds
The childhood obesity rate in the United States may increase by 2.4% if school closures continue into December, finds a new study from the Brown School at Washington University in St. Louis. Having schools closed nationwide, children in the U.S. have missed their opportunity to participate in physical education classes and other school-based physical activities, such as recess and after-school sports programs.
ACADEMY OF NUTRITION AND DIETETICS SUPPORTS INTRODUCTION OF MEDICAL NUTRITION THERAPY LEGISLATION IN CONGRESS
The Academy of Nutrition and Dietetics supports U.S. Rep. Eliot Engel (N.Y.) and Rep. Pete King’s (N.Y.) commitment to America’s health by introducing the Medical Nutrition Therapy Act of 2020. The bill would provide coverage for Medicare beneficiaries to obtain treatment from registered dietitian nutritionists and other qualified nutrition experts for many common and costly chronic diseases.
Warwick scientists discover how cells respond to fasting
The UK has the highest level of obesity in Europe, in fact it’s estimated half the population could be obese by 2050. Obesity is a significant risk factor for increased morbidity and mortality
$5.75M grant to help researchers study role of obesity in development of pancreatic cancer
A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer. The scientists hope their findings may help people avoid getting this cancer.
Inspiring stories from women like themselves helped these moms improve their diet
When researchers asked overweight low-income moms who should be in study videos promoting healthy lifestyle behaviors, moms said they wanted to see themselves. The researchers obliged. And the intervention they designed produced the desired results when it came to improving participants’ diet.
Announcing NUTRITION 2020 LIVE ONLINE
Journalists and bloggers are invited to attend NUTRITION 2020 LIVE ONLINE, a dynamic virtual event showcasing new research findings and timely discussions on food and nutrition. The online meeting will be held June 1–4, 2020.
Excess coffee consumption a culprit for poor health
Cappuccino, latte or short black, coffee is one of the most commonly consumed drinks in the world. But whether it’s good or bad for your health can be clarified by genetics, as a world-first study from the University of South Australia’s Australian Centre for Precision Health shows that excess coffee consumption can cause poor health.
Insulin Resistance Contributes to Racial Disparities in Breast Cancer Prognosis in U.S. Women, Mount Sinai Researchers Reveal
New study identifies that differences in insulin resistance can explain in part the disparities in breast cancer survival between black and white women
Diabetes Drug May Protect Breastfed Children from Future Metabolic Disorder
A new study suggests that treating a breastfeeding parent with a common diabetes drug may provide male offspring lifelong protection against diabetes and obesity. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism. It was chosen as an APSselect article for May.
Diabetes Drug May Protect Breastfed Sons from Future Metabolic Disorder
Article title: Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner Authors: Zach Carlson, Hannah Hafner, Molly Mulcahy, Kaylie Bullock, Allen Zhu, Dave Bridges, Ernesto Bernal-Mizrachi, Brigid Gregg From the authors: “Future…
Obese adults facing Medicaid expansion gap
Despite overall increases in insurance coverage for low-income individuals in Medicaid expansion states, some gaps remain for individuals who are obese.
Study points to obesity as driver of pancreatic cancer
A new study led by Yale Cancer Center (YCC) researchers has demonstrated in mice that hormones released from the pancreas itself can advance pancreatic cancer — and that weight loss can stop this process in its early stages. The research was published today in the journal Cell.
Brown fat can burn energy in an unexpected way
Joslin researchers have found a pathway that can boost the production of (heat-generating, fat-burning) brown fat cells without also creating unhelpful white fat cells. This finding suggests that the pathway the Joslin team uncovered might offer a solution to that challenge.
Liraglutide can help adolescents with obesity manage their weight
Liraglutide 3.0 mg, approved by the United States Food and Drug Administration (FDA) as an adjunct to a reduced-calorie diet and increased physical activity to help adults with obesity manage their weight, appears to help adolescents too, according to an industry-sponsored randomized controlled trial. The study was accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a supplemental issue of the Journal of the Endocrine Society.
Unconscious food cravings may make bariatric surgery less effective for people with extreme obesity
Patients with extreme obesity are prone to unconscious food impulses and cravings that may make it challenging for them to maintain weight loss after bariatric surgery, according to research that was accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.
Coconut oil reduces features of metabolic syndrome in obese females, animal study finds
Obese females that ate a small amount of coconut oil daily, even as part of a high-fat diet, had decreased features of metabolic syndrome, a cluster of risk factors that raise the chances of developing diabetes, heart disease and stroke, an animal study finds. The study results were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.
Poor fitness may impede long-term success in weight loss program
People who are very out of shape when they begin a behavioral weight loss program lose less weight in the long term than those who are more fit, suggests a new study that was accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.