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UrduMount Sinai study also shows catching up on sleep doesn’t reverse possible negative effects on cellular level
Tag: Heart Disease
Valentin Fuster, MD, PhD, Receives Prestigious Award from Cardiovascular Research Foundation
Mount Sinai Heart leader will be recognized for his exceptional career achievements at the 34th annual conference.
Risk factors for heart disease and stroke largely similar in men and women globally
The global study assessed risk factors, including metabolic (such as high blood pressure, obesity and diabetes), behavioural (smoking and diet), and psychosocial (economic status and depression) in about 156,000 people without a history of CVD between the ages of 35 and 70. Living in 21 low, middle and high-income countries on five continents, they were followed for an average of 10 years.
Low-Cost Disease Diagnosis by Mapping Heart Sounds
In the Journal of Applied Physics, researchers develop a method to identify aortic valve dysfunction using complex network analysis that is accurate, simple to use, and low-cost. They used heart sound data to create a complex network of connected points, which was split into sections, and each part was represented with a node. If the sound in two portions was similar, a line was drawn between them. In a healthy heart, the graph showed two distinct clusters of points, with many nodes unconnected. A heart with aortic stenosis contained many more correlations and edges.
Researchers warn of potential threat to heart health from extreme weather
An analysis in nearly 2.3 million Europeans has found detrimental associations between cold weather and deaths from heart disease, particularly in poor neighbourhoods.
University Hospitals Studying a Self-Management Treatment for Black Women with Depression and at Risk for High Blood Pressure
Researchers at University Hospitals, with support from an American Heart Association® grant, will work to better understand how to successfully treat Black women diagnosed with depression who are also at risk for high blood pressure.
Hackensack University Medical Center Becomes Second Hospital in the World to Implant New Heart Pump to Treat Chronic Heart Failure
Hospital is one of only five in the U.S. selected to participate in early clinical trial for the minimally invasive Impella BTR technology
New educational alliance between the American Heart Association and the Cardiovascular Research Foundation announced
Two leaders in cardiovascular disease science, research and education, the American Heart Association (Association) and the Cardiovascular Research Foundation (CRF), are joining forces to strengthen and expand educational opportunities focused on advancing the latest research in cardiovascular disease and interventional therapies. The new alliance to produce joint education programs begins immediately with the organizations’ annual scientific meetings this fall. The Association will present educational programming from its annual Scientific Sessions at TCT, and CRF will deliver educational programming from its annual scientific symposium Transcatheter Cardiovascular Therapeutics (TCT) at the Association’s Scientific Sessions, beginning with TCT 2022, September 16-19 in Boston, and the Association’s Scientific Sessions 2022, November 5-7 in Chicago, respectively.
Ochsner and Tulane collaboration uncovers what happens to genes inside artery plaques to trigger strokes
Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that become active in carotid arteries when plaque rupture causes a stroke. The work, published in Scientific Reports, was made possible by acquiring samples closer to the time of the stroke than previously possible. The results provide a picture of what the cells in the plaque are doing near the moment they induce a stroke.
Down on Vitamin D? It could be the cause of chronic inflammation
World-first genetic research from the University of South Australia shows a direct link between low levels of vitamin D and high levels of inflammation, providing an important biomarker to identify people at higher risk of or severity of chronic illnesses with an inflammatory component.
Increased heart disease risk from red meat may stem from gut microbe response to digestion
Chemicals produced in the digestive tract by gut microbes after eating red meat may help explain part of the higher risk of cardiovascular disease associated with red meat consumption, according to new research published today in the American Heart Association’s peer-reviewed journal Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).
Old-School Health Assessment Beats Genetic Test for Predicting Heart Disease
A genetic risk for heart disease is far less predictive of problems than actual lifestyle risk factors such as high blood pressure, high cholesterol and diabetes — even among younger adults.
Scientists discover genes that affect the risk of developing pre-leukaemia
The discovery of 14 inherited genetic changes which significantly increase the risk of a person developing a symptomless blood disorder associated with the onset of some types of cancer and heart disease is published today in Nature Genetics. The finding, made in one of the largest studies of its kind through genetic data analysis on 421,738 people, could pave the way for potential new approaches for the prevention and early detection of cancers including leukaemia.
Exercise + Sauna = Better Cardiovascular Function
New research suggests that adding a regular 15-minute sauna to an exercise routine may improve cardiovascular risk factors more than exercise alone. The study is the first randomized controlled trial to explore the long-term combination of exercise and sauna bathing in a non-clinical population. It is published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.
Where and When Violent Crime Rates Fall, Heart Disease Deaths Fall, Too
A new study of data from Chicago found that the neighborhoods where violent crime fell the most, cardiovascular disease mortality fell sharply, too
UChicago Medicine’s Community Health Needs Assessment identifies cancer, heart disease as health priorities for South Side
The University of Chicago Medicine released its 2021-22 Community Health Needs Assessments (CHNA) for the communities the health system serves on Chicago’s South Side and in the south suburbs.
People of East Asian Descent Have More Vessels Reclog After Endovascular Treatment
Among people who received endovascular therapy to mechanically remove a clot in their large brain artery, those who had a rare genetic variant found primarily in people of East Asian descent (Japanese, Chinese and Korean) were more likely to have the vessel reclog during or shortly after the procedure, according to a small study published today in Stroke: Vascular and Interventional Neurology, an open access journal jointly published by the American Heart Association/American Stroke Association and the Society of Vascular and Interventional Neurology.
Blinding Eye Disease Is Strongly Associated With Heart Disease and Stroke
Patients with a specific form of age-related macular degeneration (AMD), a leading cause of blindness in the United States, are at significant risk for cardiovascular disease and stroke, according to new research from New York Eye and Ear Infirmary of Mount Sinai.
Study shows HIV speeds up body’s aging processes soon after infection
HIV has an “early and substantial” impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection.
Stalling Improvements in Cardiovascular Disease Rates Since 2010 Could Cost £54bn Between 2020 and 2029
New research published today suggests that the slowdown in improvements in cardiovascular diseases like heart disease and stroke seen in England and Wales since 2010 could cost £54billion in health and social care costs.
Vitamin D Supplements May Offset Bone Loss Caused by Diabetes Drug
Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug. Researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
Specific Environmental Exposures may Help Predict Increased Risk of Death from Cardiovascular Disease
A new study from the Icahn School of Medicine at Mount Sinai quantifies the cardiovascular risk posed by exposure to specific environmental factors, showing, for example, that air pollution heightens the risk of heart disease mortality by 17 percent.
Women’s heart attacks are often missed. This gene may help explain why.
Newly identified genes may help explain why women experience different heart disease symptoms than men do, which often leads to misdiagnosing serious problems.
Faculty Scientists and Clinicians Publish Findings of World’s First Successful Transplant of Genetically Modified Pig Heart into Human Patient
Six months ago, University of Maryland School of Medicine surgeon-scientists successfully implanted a genetically modified pig heart into a 57 year-old patient with terminal heart disease in a first-of-its-kind surgery.
Heart Failure Patients Unvaccinated Against COVID-19 Are Three Times More Likely to Die From It Than Boosted Heart Failure Patients
EMBARGOED UNTIL JUNE 9, 2022, 10AM EST (New York, NY – June 9, 2022) – Heart failure patients who are unvaccinated against SARS-CoV-2, the virus that causes COVID-19, are three times more likely to die if infected with the virus…
Researchers Establish a Profile of the COVID-19 Deceased Based on the Analysis of 140 Cases of Complete Autopsies
Men aged between 60 and 77 with Diffuse Alveolar Damage (DAD) –acute lung injury– in proliferative phase.
Blocking Endothelin Receptors May Help People with Obesity Burn Calories, Reduce Heart Disease Risk
Article title: Dual endothelin receptor antagonism increases resting energy expenditure in people with increased adiposity Authors: Cassandra C. Derella, Anson M. Blanks, Andy Nguyen, Jacob Looney, Matthew A. Tucker, Jinhee Jeong, Paula Rodriguez-Miguelez, Jeffrey Thomas, Matthew Lyon, David M. Pollock,…
Clarkston health fair offers free screenings, fun family activities for people with diabetes
Endocrine experts will provide free health services and fun family activities to the local refugee and immigrant community of DeKalb County during EndoCares® Atlanta, an in-person health education event being held on Saturday, June 11.
New Gene Identified in Arrhythmogenic Cardiomyopathy
Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells.
Ultrasound-Assisted Laser Technique Vaporizes Artery Plaque #ASA182
Atherosclerosis, a buildup of plaque, can lead to heart disease, artery disease, and chronic kidney disease and is traditionally treated by inserting and inflating a balloon to expand the artery. During the 182nd ASA Meeting, Rohit Singh, of the University of Kansas, will present a method that combines a low-power laser with ultrasound to remove arterial plaque safely and efficiently.
New research may explain unexpected effects of common painkillers
Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body.
Haywire T cells attack protein in “bad” cholesterol
Detecting these T cells may lead to diagnostics to better detect heart disease—and disease severity.
Late-Breaking Science Announced for TVT 2022
The Cardiovascular Research Foundation (CRF) announced that TVT: The Structural Heart Summit will feature 12 studies as Late-Breaking Clinical Science and Featured Clinical Research. An annual meeting covering cutting-edge research and techniques for structural heart interventions, TVT will take place June 8-10, 2022, at the Sheraton Grand Chicago Riverwalk in Chicago, Illinois.
From cavefish to humans: Evolution of metabolism in cavefish may provide insight into treatments for a host of diseases such as diabetes, heart disease, and stroke
New research examines how cavefish developed unique metabolic adaptations to survive in nutrient-scarce environments. The study created a genome-wide map of liver tissue for two independent colonies of cavefish along with river fish to understand how cavefish metabolism evolved and how this may be applicable for humans.
TVT 2022 Program Now Available
The program for TVT 2022: The Structural Heart Summit is now available online. An annual meeting from the Cardiovascular Research Foundation (CRF), TVT features cutting-edge research and techniques for structural heart interventions and will take place June 8-10, 2022 at the Sheraton Grand Chicago Riverwalk in Chicago, Illinois.
“One-size-fits-all” flawed for assessing cardiovascular disease risk among Asian Americans
In a large, retrospective study covering data from the last two decades, death rates for cardiovascular diseases in the U.S. varied among people from various Asian ethnicity subgroups, with death rate trends that stagnated in some subgroups and increased in others, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, a peer-reviewed journal of the American Heart Association.
Seattle health fair offers free screenings, wellness activities for people with diabetes
Endocrine experts will deliver free health services to underrepresented communities, including Latinx and Hispanic residents, during EndoCares® Seattle, an in-person health education event being held on May 14.
Media Registration for TCT 2022 Now Open
Media registration is now open for TCT 2022 (Transcatheter Cardiovascular Therapeutics), the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT will be held September 16-19, 2022, in Boston, Massachusetts at the Boston Convention and Exhibition Center.
Researchers ID Post-exercise Changes in MicroRNA as Potential Markers for Coronary Artery Disease
Article title: Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise Authors: Maria Dalen Taraldsen, Rune Wiseth, Vibeke Videm, Anja Bye, Erik Madssen From the authors: “This exploratory study demonstrated six miRs associated with coronary necrotic…
Mayo researchers use AI to detect weak heart pump via patients’ Apple Watch ECGs
Single-lead ECG tracings from an Apple Watch interpreted by an artificial intelligence (AI) algorithm developed at Mayo Clinic effectively identified patients with a weak heart pump.
Could exercise counteract cardiotoxic chemotherapy for women with breast cancer
When you’re a breast cancer survivor, the last thing you need is another health scare. So, it’s concerning to know that up to 48 per cent of breast cancer patients will go on to fight heart disease as a direct result of chemotherapy.
New study finds childhood abuse linked to higher risk for high cholesterol as an adult
A new study found risk factors for heart disease and stroke were higher among adults who said they experienced childhood abuse and varied by race and gender.
Stress during Pregnancy May Lead to Heart Disease, Accelerated Aging in Next Generation
Prenatal stress can cause damage in the aorta in offspring, which may contribute to the development of atherosclerosis and accelerate aging, according to a new study in mice. The article is published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.
People with diabetes and cognitive decline may be at higher risk for heart disease
People with type 2 diabetes who have cognitive impairment could be at greater risk for stroke, heart attack or death than other individuals with diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism.
Investigational Anti-Clotting Drug Reduces Bleeding Risk Among AF Patients
A new type of anti-clotting drug caused fewer bleeding incidents among patients with atrial fibrillation than the commonly prescribed apixaban, according to results from a head-to-head comparison of the two.
Few Patients Have Infected Heart Devices Removed Despite Lifesaving Benefits
Medicare patients whose implantable heart devices became infected were less likely to die from the complication if they had the hardware removed compared to patients who only received antibiotics, according to the largest study on the topic, led by the Duke Clinical Research Institute.
Investigational Drug for Heart Failure has Little Impact on Exercise Tolerance
Heart failure patients taking the investigational drug omecamtiv mecarbil, which has been previously shown to improve long-term outcomes, see little impact on their ability to exercise compared to a placebo, according to a study supported by the Duke Clinical Research Institute.
Cleveland Clinic-Led Trial Finds That Experimental ‘Gene Silencing’ Therapy Reduces Lipoprotein(a), an Important Risk Factor of Heart Disease, By Up To 98%
Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental “gene silencing” therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.
Findings from the “APOLLO Trial: Magnitude and Duration of Effects of a Short-interfering RNA Targeting Lipoprotein(a): A Placebo-controlled Double-blind Dose-ranging Trial” were presented today during a late-breaking science session at American College of Cardiology’s 71st Annual Scientific Session and simultaneously published online in the Journal of the American Medical Association.
Cleveland Clinic-Led Trial Shows Drug Effective in Nearly 80% of Patients with Hypertrophic Cardiomyopathy
Findings from a Cleveland Clinic-led clinical trial showed that the use of an experimental drug in severely symptomatic, hypertrophic cardiomyopathy patients significantly reduced the need for invasive procedures.
Exercise Improves Health Markers in Young Female Survivors of Childhood Trauma
New research shows a progressive exercise training program mitigates some physiological and psychological effects of adverse childhood experiences in otherwise healthy young women. The study will be presented at the American Physiological Society annual meeting at Experimental Biology 2022.