news, journals and articles from all over the world.
A research team at Iowa State University has found that zinc supplements may be an inexpensive, effective antidote to the growing health threat of antimicrobial resistance, potentially extending the effectiveness of today’s antibiotic arsenal against disease.
A research team investigates how mucin, a major component of the gut lining, and food-derived glycoproteins influence the growth of this bacterium.
Gut bacteria may be associated with differences in brain structure and clinical symptom severity in people with alcohol use disorder.
Study finds that mesalamine, a common anti-inflammatory drug, can fight the fungus Candida albicans in the gut, potentially preventing the risk of invasive candidiasis in patients with blood cancers.
Australian scientists are exploring how harmful gut bacteria from a poor diet can access the brain and trigger early onset Alzheimer’s disease.
New research suggests that cultivating a healthy gut microbiome could help astronauts weather the stresses of altered gravity. Researchers will present their work this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society, in Long Beach, California
Researchers have identified multiple species of bacteria that, when present in the gut, are linked to an increased risk of developing severe malaria in humans and mice. Their findings could lead to the development of new approaches targeting gut bacteria to prevent severe malaria and associated deaths.
Gut microbes found in wild wolves may be the key to alleviating a debilitating gastrointestinal condition common to domestic dogs, according to a study led by researchers at Oregon State University – Cascades.
The findings point to possible mechanisms behind intestinal conditions like Crohn’s disease and ulcerative colitis, and also suggest avenues to develop more effective probiotics.
There is growing evidence that consuming prebiotics — certain types of fiber often found in plants that stimulate beneficial bacteria in your gut — can help to maintain a healthy gut microbiome. In a new study, scientists estimated the prebiotic content of thousands of food types by using preexisting literature to find out which foods offer the highest prebiotic content.
UNLV study pinpoints 10 bacterial groups associated with Alzheimer’s disease, provides new insights into the relationship between gut makeup and dementia.
The discovery shows why it can be so difficult to tackle drug-resistant bacteria, but does provide a possible avenue for tackling the problem.
The discovery of a strain of bacteria shown to reduce inflammation in the intestine caused by irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) could bring relief to millions of sufferers after being turned into an innovative natural food supplement by University of Bristol biotech spin-out Ferryx.
A new University of Michigan study reveals the gut microbiome’s role in regulating body temperature.
University of Oregon neuroscientists discovered a pathway linking microbes in the gut to those in the brain, which could lead to new treatments for neurodevelopmental conditions.
Two weeks of eating a diet heavy in tomatoes increased the diversity of gut microbes and altered gut bacteria toward a more favorable profile in young pigs. After observing these results with a short-term intervention, the research team plans to progress to similar studies in people.
New UCLA-led research suggests certain gut bacteria — including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected. The findings, published in the peer-reviewed journal eBioMedicine, suggest that the gut microbiome could contribute to one’s risk for HIV infection, said study lead Dr.
The McMaster-Queen’s research team pinpointed the bacterium Klebsiella aerogenes as the key histamine producer by studying germ-free mice colonized with gut microbiota from patients with IBS. They also colonized some mice with gut microbiota from healthy volunteers as a control group.
The study found that the bacterium Klebsiella aerogenes converts dietary histidine, an essential amino acid present in animal and plant protein, into histamine, a known mediator of pain.
The study findings suggest possibilities for developing new drugs that replicate or build on A. muciniphila’s immuno-modulatory activity.
The work provides a model for using traditional techniques to pinpoint how other members of the gut microbiome act on the body.
The National Institutes of the Health (NIH) has awarded researchers at the Icahn School of Medicine at Mount Sinai a four-year grant to study the role of the human microbiome in rheumatoid arthritis, systemic lupus, and other autoimmune diseases. The grant is part of the NIH’s Accelerating Medicines Partnership® Autoimmune and Immune-Mediated Diseases (AMP® AIM) program, which is designed to speed the discovery of new treatments and diagnostics. It will support the Microbiome Technology and Analytic Center Hub (Micro-TEACH), a multidisciplinary team of researchers at Icahn Mount Sinai and NYU Langone Health.
Chula’s Faculty of Medicine pioneers Thailand’s first research work that studies “Intestinal Microflora Microbiome of the Aged” which gathers basic information at the national level to unlock the relationship between the wellness of the aged and intestinal microflora that can predict risks of diseases and health and the population’s wellbeing.
Gut reaction: Cornell researchers “humanized” mice with microbiota from three global populations and found that microbial differences alone can impact immune responses.
New findings from Cleveland Clinic researchers show for the first time that the gut microbiome impacts stroke severity and functional impairment following stroke. The results, published in Cell Host & Microbe, lay the groundwork for potential new interventions to help treat or prevent stroke. The research was led by Weifei Zhu, Ph.D., and Stanley Hazen, M.D., Ph.D., of Cleveland Clinic’s Lerner Research Institute.
Rockville, Md. (April 22, 2021)—Researchers from the Medical College of Wisconsin (MCW) report in new research that gut bacteria burn a significant percentage of calories from food that we ingest. Those calories then get absorbed and converted to adipose (fat)…
New research led by a University of Georgia faculty member in collaboration with a University of Southern California research group has shown in a rodent model that daily consumption of sugar-sweetened beverages during adolescence impairs performance on a learning and memory task during adulthood. The group further showed that changes in the bacteria in the gut may be the key to the sugar-induced memory impairment.
ST. LOUIS – The gut is like your second brain and can have a significant impact on your overall health, advises a nutrition expert. Whitney Linsenmeyer, Ph.D., assistant professor of nutrition and dietetics at Saint Louis University and spokesperson for…
An enzyme in the colon lining releases hydrogen peroxide – a known disinfecting compound- to protect the body from gut microbial communities. Findings from the UC Davis Health study points to importance of considering a different approach to treating gut inflammation and bacterial imbalance in the colon.
Liver failure – often due to acetaminophen overdose – is fatal in 80% of cases. The labs of Profs. Ido Amit and Eran Elinav discovered three liver-cell subsets that contribute to disease progression, and found that depleting the microbiome acts on those subsets to reduce liver damage and increase survival rates. The research may lead to treatments for liver failure.
Published in this month’s edition of Toxicological Sciences are articles on biotransformation, toxicokinetics, and pharmacokinetics; developmental and reproductive toxicology; nanotoxicology; and more.
Scientists have discovered that one of the good bacteria found in the human gut has a benefit that has remained unrecognized until now: the potential to reduce the risk for heart disease.
The role genetics and gut bacteria play in human health has long been a fruitful source of scientific enquiry, but new research marks a significant step forward in unraveling this complex relationship.
The Memorial Sloan Kettering – Hackensack Meridian Health Partnership has formed an Immunology Research Collaboration, through which researchers can apply for funding to support innovative investigations to explore the power of the immune system and ways it may be harnessed to fight cancer. Three researchers’ projects were selected in 2020 for funding support.
Infants who were started on solid foods at or before three months of age showed changes in the levels of gut bacteria and bacterial byproducts, called short-chain fatty acids, measured in their stool samples, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.
Researchers at Washington University School of Medicine in St. Louis and Mayo Clinic in Rochester, Minn., have found — in newborn mice — that a component of breast milk may help protect premature babies from developing life-threatening sepsis.
Gut bacteria can penetrate tumor cells and boost the effectiveness of an experimental immunotherapy that targets the CD47 protein.
Popular diets low in carbs and high in fat and protein might be good for the waistline, but a new UNLV study shows that just the opposite may help to alleviate the hospital-acquired infection Clostridioides difficile. The results appeared in a study published Feb. 11 in mSystems, an open access journal of the American Society for Microbiology.
Scientists studied how the bacteria transport electrons across their cell wall. The bacteria use a method that’s different from other, known electricity-producing bacteria. They also found that hundreds of other bacterial species use this same process.
The December 2019 issue of Toxicological Sciences features research on the leading edge of toxicology, including in the areas of carcinogenesis, developmental and reproductive toxicology, and more.
A UC Davis study found that Lactobacillus plantarum bacteria rapidly repaired damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus. It linked chronically inflamed leaky gut to the loss of PPARα signaling and damage to mitochondria.
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