In a substantial milestone for supercomputing-aided drug design, Lawrence Livermore National Laboratory (LLNL) and BridgeBio Oncology Therapeutics (BridgeBio) today announced clinical trials have begun for a first-in-class medication that targets specific genetic mutations implicated in many types of cancer.
Month: June 2024
To hire the right job candidate, humans and machines should clear up this simple miscommunication
Hiring teams need to teach machine learning algorithms how hiring works to find the best candidates.
Neurent Medical Announces Publication of Positive Long-Term Results from Study on Chronic Rhinitis Treatment
Recent study confirms safety and efficacy of NEUROMARK® for chronic rhinitis
Rensselaer Researchers Upend Theory About the Formation of the Milky Way Galaxy
Rensselaer Polytechnic Institute’s Heidi Jo Newberg, Ph.D., professor of astronomy; Tom Donlon, Ph.D., a visiting researcher at Rensselaer and a postdoctoral researcher at the University of Alabama; and their team have recently published research that reveals a shocking discovery about the history of our universe: the Milky Way Galaxy’s last major collision occurred billions of years later than previously thought.
Mount Sinai Health System named 2024 Hearst Health Prize winner
Hearst Health and the UCLA Center for SMART Health awarded the 2024 Hearst Health Prize to Mount Sinai Health System. Mount Sinai Health System was declared the winner for a machine learning application called NutriScan AI that facilitates faster identification and treatment of malnutrition in hospitalized patients.
How to Build a Team of ‘Appropriately Skeptical’ Financial Statement Auditors
A new study identifies the characteristics that make auditing professionals more likely to reward skepticism in the people they supervise, which is associated with an increased likelihood of identifying potential fraud during the auditing process.
Unlocking banana disease resistance: key enzymes identified for phytoalexin synthesis
A breakthrough in banana disease resistance was achieved with the identification of novel O-methyltransferases (OMTs) involved in the biosynthesis of phenylphenalenone phytoalexins. These compounds, found in wild bananas, hold promise for developing disease-resistant commercial cultivars.
UL Solutions and ScienceMedia Partner to Revolutionize Training and e-Learning Solutions for Life Sciences
ScienceMedia announced today that it has formed a partnership with UL Solutions that offers ComplianceWire®, the industry leading learning management system (LMS) tailored toward compliance and qualification management within life sciences organizations.
Citrus saviors: discovering the genetic defense against Huanglongbing disease
A recent study has pinpointed two key enzymes in Citrus sinensis that play a crucial role in the plant’s defense mechanism against the Asian citrus psyllid (ACP), a vector for the lethal huanglongbing (HLB) disease. This research offers a promising lead in the battle against a disease that has caused significant losses in the citrus industry.
FDA Green-Lights Moderna Vaccine for Older Adults
The US Food and Drug Administration has approved Moderna’s mRNA vaccine for older adults to protect against respiratory syncytial virus (RSV). The vaccine, called mRESVIA, is for people ages 60 and older. According to a company press release, this marks…
Desert hero unveiled: Cissus quadrangularis genome decodes drought survival tactics
In a recent study, scientists have unlocked the genetic secrets of Cissus quadrangularis, a plant that flourishes in the harshest of desert climates. The discovery of its adaptive traits and the Crassulacean acid metabolism (CAM) pathway marks a significant leap forward in the quest for drought-resistant crops.
From greenhouse to desert: ethylene receptor’s role in rose salt tolerance unveiled
A study reveals a novel mechanism in roses where the Tryptophan-rich sensory protein (TSPO) degrades the ethylene receptor ETHYLENE RESPONSE 3 (RhETR3) to enhance salt tolerance.
Vigorous Exercise May Preserve Cognition in High-Risk Patients With Hypertension
People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study from researchers at Wake Forest University School of Medicine suggests that engaging in vigorous physical activity more than once a week can lower that risk.
Cleveland Clinic-Led Study Links Sugar Substitute to Increased Risk of Heart Attack and Stroke
Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.
Flower power: genetic insights into the Chrysanthemum’s architectural elegance
Researchers have made significant strides in understanding the genetic factors that shape the Chrysanthemum lavandulifolium’s inflorescence, with a particular focus on the cla-miR164-NO APICAL MERISTEM (ClNAM) gene’s regulatory functions. This study provides a foundation for advancements in the targeted breeding and genetic enhancement of this species.
Tempo Therapeutics Announces Appointment of Eric I. Richman to Board of Directors
Tempo Therapeutics, Inc. (“Tempo”), a leading innovator in tissue engineering and regenerative medicine, today announced the addition of Eric I. Richman, MBA to its board of directors.
Introduction of Breast Imaging Legislation Will Benefit Thousands of Ohioans
Breast imaging legislation in Ohio will save thousands of lives.
Hridesh Rajan named new dean of Tulane University School of Science and Engineering
Hridesh Rajan has been named new dean of Tulane University School of Science and Engineering, effective July 1.President Michael A. Fitts and Provost Robin Forman made the announcement in a message to the Tulane community.
How a protein component of nuclear pore complexes regulates development of blood cells and may contribute to myeloid disorders
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation.
Drug Used to Treat Eczema May Provide Relief for Patients with Intensely Itchy Skin Diseases
Clinical Trial Finds Oral Medication Significantly Reduced Prurigo Nodularis and Chronic Pruritus of Unknown Origin Symptoms A drug approved to treat eczema provided significant improvement in the symptoms of patients with severe itching diseases that currently have no targeted treatments, according to a new study published in JAMA Dermatology.
MSU research: What makes a good headline?
According to research from Michigan State University, news readers engage more with simple writing, suggesting journalists should write simply — clearly and without ambiguity — to attract attention online.
Boosting key protein in eye cells could prevent age-related vision loss, international team finds
Increasing the levels of a key protein in the cells at the back of the eye could help protect against the leading cause of vision loss among older adults, finds a new discovery made by researchers from the UK, US, Germany and Australia.
Brain Overgrowth Dictates Autism Severity, New Research Suggests
Some children with autism thrive, while others require lifelong care. Now scientists know why — and the reason begins in the womb.
MD Anderson Research Highlights for June 5, 2024
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
10 UC Irvine faculty members named Hellman Fellows for 2024-25
Ten assistant professors at the University of California, Irvine will receive Hellman Fellowships, which are bestowed annually to support research by junior faculty. They join an elite group of 85 UCI Society of Hellman Fellows since 2013, when the Hellman Fellows Fund was established here.
UWF to offer new behavior analysis degree
UWF is launching a Master of Science in Behavior Analysis beginning in Fall 2024, pending approval from the Florida Board of Governors. The proposed graduate degree will be offered online and housed in the Health Sciences & Administration within the Usha Kundu, MD College of Health.
Fountain of youth for plants: E3 ligase’s role in leaf longevity
A new study uncovers the intricate molecular mechanisms that regulate leaf senescence in apple plants, focusing on the crucial role of the E3 ligase enzyme, MdPUB23, and its interaction with the ABI5 protein.
Unlocking salt resistance: sea lavender’s genetic secret revealed
Recent research has uncovered the genetic mechanisms behind sea lavender’s (Limonium bicolor) salt tolerance by studying basic helix–loop–helix (bHLH) transcription factors.
Largest-ever antibiotic discovery effort uses AI to uncover potential cures in microbial dark matter
Almost a century ago, the discovery of antibiotics like penicillin revolutionized medicine by harnessing the natural bacteria-killing abilities of microbes. Today, a new study co-led by researchers at the Perelman School of Medicine at the University of Pennsylvania suggests that natural-product antibiotic discovery is about to accelerate into a new era, powered by artificial intelligence (AI).
Many Firearm Owners Can’t Recognize When a Cable Lock Is Properly Installed
Rutgers researchers find firearm owners have gaps in their knowledge about proper lock installation on firearms
Cannabis use common among patients, with most using it to manage a symptom or health condition
Nearly one in six patients in primary care reported cannabis use, with 35% of those using at levels indicating moderate- to high-risk use disorder. The findings indicate the need for routine cannabis use screening. Currently few healthcare systems offer this screening in primary care settings.
Green Era Campus and Argonne align to forge community partner–focused agreement
Argonne National Laboratory’s Office of Community Engagement has established a Memorandum of Understanding with Chicago’s Green Era Campus to pursue research in sustainability in agriculture, renewable energy generation, and food equity and access.
Confronting climate change: the genetic makeover of a threatened conifer
A rare conifer, Cupressus gigantea, has an unexpectedly lower genetic load despite its dwindling population size. This study explores the evolutionary strategy behind its survival, focusing on the purging of deleterious mutations that contribute to its enduring legacy in the face of climate change and habitat fragmentation.
Injury Prediction Rule Could Decrease Radiographic Imaging Exposure in Children, Study Shows
In a study published today in The Lancet Child & Adolescent Health, researchers in the Pediatric Emergency Care Applied Research Network (PECARN) created a highly accurate cervical spine injury prediction rule. When applied, the rule decreases the use of CT by more than 50% without missing clinically significant injuries or increasing normal X-ray use.
Unlocking the transformative power of incorporating music in family life: A Family Guide to Parenting Musically
You don’t need to be musically inclined to parent musically. But incorporating music in your family’s daily life can foster deeper connections with each other—and with music itself.
Massachusetts Patients now Have Increased Access to Anesthesia Care
Massachusetts patients now have increased access to safe, affordable anesthesia care. The state is the latest to opt out from federal regulations that require physician supervision of Certified Registered Nurse Anesthetists (CRNAs), also known as nurse anesthesiologists or nurse anesthetists.
Rare Disease’s DNA-Damaging Mutation Could Have Consequences for More Common Conditions
In their pursuit to discover the mechanism behind how RVCL does its damage, researchers found some clues to the DNA damage theory of aging
When mothers and children talk about problems, environment matters
Talking to their parents about daily stressors can help adolescents deal with their problems. This is particularly important during the transition to middle school, when youth often are faced with new peer and academic challenges. But does it matter where these conversations take place? That’s the topic of a new study from the University of Illinois Urbana-Champaign.
Study Reveals Billion-Dollar Toll of Domestic Violence in California
A comprehensive new study by Tulane University’s Newcomb Institute and the University of California San Diego School of Global Policy and Strategy has quantified the staggering economic impact of intimate partner violence in California, revealing billions in costs that deeply affect survivors, communities and taxpayers across the state.
Researchers use machine learning to detect defects in manufacturing
The algorithm was able to correctly identify hundreds of defects in real physical parts that have not previously been seen by the deep learning model.
How tumor stiffness alters immune cell behavior to escape destruction
Researchers at Sanford Burnham Prebys, with collaborators, illuminate how the fibrotic tumor microenvironment creates an inhospitable milieu for anti-tumor immunity, not just by creating a physical barrier but through metabolic changes that suppress the anti-tumor function of responding immune cells.
Canisius University experts dissect impact of President Biden’s executive order and its broader socio-political context
In response to President Joe Biden’s announcement today, Tuesday, June 4, limiting the border crossing of asylum-seekers, Canisius University professors Richard Reitsma, PhD and Shyam Sriram, PhD, are available to provide expert commentary. Both bring a wealth of expertise to…
Emma Guttman-Yassky, MD, PhD, Receives High Honor at European Academy of Allergy and Clinical Immunology
The Paul Ehrlich Award for Experimental Research recognizes scientists who have revolutionized the understanding of allergic diseases and immunological mechanisms.
An anti-inflammatory curbs spread of fungi causing serious blood infections
Study finds that mesalamine, a common anti-inflammatory drug, can fight the fungus Candida albicans in the gut, potentially preventing the risk of invasive candidiasis in patients with blood cancers.
Wayne State University partners with Great Lakes Water Authority to help train water pipeline managers of the future
The Great Lakes Water Authority (GLWA) has partnered with Wayne State University to develop its Workforce Development and Pipe Management Program, which will help recruit, teach and graduate the next generation of water pipeline managers. The two-year program will begin July 1, 2024, and will be supported by a contract totaling more than $480,000.
The Glaucoma Foundation Expands Board of Directors
Two prominent ophthalmologists join the TGF Board.
Programs to Prevent Sexual Violence Show No Evidence of Curbing Assaults
Sexual violence prevention programs effectively change ideas and beliefs that underscore assaults, but show no evidence of reducing their actual occurrence, a new analysis shows.
Q&A: Social Media and Youth Mental Health Expert Sarah Domoff
ALBANY, N.Y. (June 4, 2024) — New York State legislators are poised to pass new regulations designed to limit the ways social media companies use algorithms to target content shared with young users. The proposed legislation focuses on features of…
UC San Diego Health First in Region to Provide Novel Therapy for Melanoma
Breakthrough one-time cancer treatment option for select patients with metastatic melanoma and solid tumors now offered at UC San Diego Health.
FAU and Mainstreet Research Poll of Battleground States Highlights Partisan Divide on Top Issues, Trump Conviction
A new poll of voters in Pennsylvania, Michigan and Wisconsin, often considered battleground states, highlights the partisan divide on important issues and on the legal case against former U.S. President Donald Trump.