MD Anderson Research Highlights for July 27, 2022

Clinical advances include treating hematologic cancers with effective targeted therapies, circulating tumor DNA as a biomarker for recurrence with colorectal liver metastases, and using magnetic resonance imaging (MRI) to guide surgical decisions for patients with lateral pelvic lymph node metastases in rectal cancer. Laboratory findings offer new understanding of the pancreatic cancer immune microenvironment, melanoma cell states, TP53 mutation status in acute myeloid leukemia (AML), and potential targets for metastatic prostate cancer and GNAS-mutant colorectal cancer.

Sylvester Leads Study on New Treatment Option for Brain Tumor that Relapses or Fails to Respond to Standard of Care

Taken twice daily, oral olutasidenib helped to stabilize relapsed or refractory gliomas in heavily pretreated patients with less toxicity than standard of care treatment, according to a study led by Sylvester Comprehensive Cancer Center at the University of Miami School…

New Public-Private Partnership to Upgrade Tool That Estimates Costs of Power Interruptions

Berkeley Lab has initiated a national public-private partnership to update and upgrade the Interruption Cost Estimate (ICE) Calculator – a publicly available, online tool – which estimates the economic consequences of power interruptions.

Intravesical chemotherapy combination provides effective treatment alternative for high-risk non-muscle invasive bladder cancer

A combination of two intravesical chemotherapy drugs – gemcitabine and docetaxel – yields high response rates with good tolerability in patients with high-risk non-muscle-invasive bladder cancer (NMIBC), reports a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Leadership program prepares professionals to respond to public health crises in Puerto Rico

A program called “Advancing Leadership in Times of Crisis” (ALTC) has helped to increase leadership skills and knowledge among public health professionals in Puerto Rico – preparing them to adapt and respond to the challenges posed by a series of public health emergencies, reports a study in a supplement to the September/October issue of the Journal of Public Health Management and Practice (JPHMP). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Vitamin B5 May Help Weight Loss by Turning on Brown Fat

Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. “[B5] has therapeutic potential for treating obesity and type II diabetes,” researchers conclude. The study was chosen as an APSselect article for July.

How to Effectively Market Influencers “Kollective”: An Innovation that Responds to Business Needs by Chula’s Start-Up

Chula alumni team in cooperation with the CU Innovation Hub has come up with the idea of “Kollective” a new start-up that provides the tools and services for full-scale marketing of influencers. With the analysis using big data, the best influencers are chosen to increase sales volumes in your business.

NCCN Publishes New Patient Guidelines for Breast Cancer Screening and Diagnosis Emphasizing Annual Mammograms for All Average-Risk Women Over 40

The National Comprehensive Cancer Network (NCCN) has published new NCCN Guidelines for Patients: Breast Cancer Screening and Diagnosis to help people understand their personal risk for breast cancer, when they should begin screening, and how often to screen—in order to detect cancer earlier, for more treatment options and better outcomes.

People respond differently to psychedelic drugs — genetics could be the reason

Psychedelic drugs have shown benefits as treatments for cluster headaches, anxiety and depression in clinical studies, but not for everyone. Now, in ACS Chemical Neuroscience, researchers report that one reason could be common genetic variations in one serotonin receptor.

To tax or not to tax, is that even a question?

A solution is proposed for evaluating tax efficiency, a formula expressing the marginal cost of public funds as a ratio of a net loss in social surplus to a net increase in tax revenue. This formula is derived from only a few indices, common across specific market demand conditions and cost factors. The indices clearly tell us how the degree of tax-driven social burden relates to imperfect competition.

Open Lab Solutions Announces New Manufacturing Division to Initially focus on Medical Plastics

CHICAGO, July 26, 2022 /PRNewswire/ — AACC 2022 Open Lab Solutions, Inc., is announcing the formation of a new division, AMCAR Scientific, that will focus on an expanding product line of plastic consumables used in the medical industry. OLS is exhibiting within booth #3257 at the 74th American Association for Clinical Chemistry Annual Scientific Meeting and Clinical Laboratory Exposition (AACC 2022) at the McCormick Place Convention Center in Chicago, July 24 – 28th.

Immunosuppressive drug’s blood level variability may identify pediatric kidney transplant recipients at risk of rejection

• Kidney transplant recipients typically take the immunosuppressant drug tacrolimus to prevent rejection, and some patients experience large fluctuations in blood levels of tacrolimus even when the dose is unchanged.
• In a recent study, pediatric kidney transplant recipients with such variability had higher risks of developing antibodies against the transplanted kidney, putting them at risk of rejection.

Study on time restricted eating reveals limiting food intake to daytime shows promising beneficial metabolic effects in adults with type 2 diabetes

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that following a time-restricted eating (TRE) protocol which limits food intake to a max 10-hour time window shows promising beneficial metabolic effects in adults with type 2 diabetes (T2D).

Virtual co-embodiment of a joint body with left and right limbs controlled by two persons

What factors influence the embodiment felt towards parts of our bodies controlled by others? Using a new “joint avatar” whose left and right limbs are controlled by two people simultaneously, researchers have revealed that the visual information necessary to predict the partner’s intentions behind limb movements can significantly enhance the sense of embodiment towards partner-controlled limbs during virtual co-embodiment.