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UrduTraditional approaches to prostate cancer screening involve blood tests, MRI, and biopsies. However, in addition to being uncomfortable, some of these procedures result in overdiagnosis of low-grade cancers.
Tag: Cancer
Moffitt Research Advocates for Routine Brain MRI Screening in Asymptomatic Late Stage Breast Cancer Patients
A new study led by researchers at Moffitt Cancer Center shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study, published in Neuro-Oncology, suggests that doctors may need to rethink current screening guidelines for detecting brain metastasis in patients without symptoms.
Novel Lab-on-Chip Platform Promises to Expedite Cancer Diagnoses
In Physics of Fluids, researchers propose a novel system that uses standing surface acoustic waves to separate circulating tumor cells from red blood cells with unprecedented precision and efficiency. The platform integrates advanced computational modeling, experimental analysis, and artificial intelligence algorithms to analyze complex acoustofluidic phenomena.
Could fecal microbiota transplantation help patients heal after stem cell transplantation?
A new study published in Nature Communications shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood cancers.
Study reveals biomarker for high risk of metastasis
A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target to block it. The findings, published in Science Signaling, represent an important lead in developing new drugs to prevent tumors from spreading, the cause of death among most patients with cancer.
Study Results: Exploring Gastric Cancer Risk Through Oral Microbiomes
New Brunswick, N.J., January 27, 2025 – Gastric cancer, also known as stomach cancer, is a type of cancer that starts in the stomach lining. Detecting the disease early can improve outcomes, but current methods are often invasive. A new study…
Cancer risk established before birth
A person’s lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study published in Nature Cancer.
Targeted nanotherapy: a new frontier for TSCC treatment
A pioneering study has unveiled the Au-HN-1 nanosystem, a cutting-edge approach that promises to transform the diagnosis and treatment of tongue squamous cell carcinoma (TSCC).
Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer
Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.
Radon: The invisible danger to homes and health
The National Cancer Institute lists radon as the second-leading cause of lung cancer behind smoking. Much of Southwest Virginia is at high risk for this colorless, odorless gas, which threatens indoor air quality and poses long-term health threats.
$10.8 million grant supports cutting-edge leukemia research
Washington University School of Medicine in St. Louis has received a renewal of a prestigious research grant from the National Cancer Institute. Led by principal investigator, Daniel Link, MD, the Specialized Program of Research Excellence (SPORE) grant in leukemia provides funding for translational research.
Governor Hochul Celebrates the Opening Of New York’s First Cell and Gene Therapy Hub at Roswell Park Comprehensive Cancer Center in Buffalo
Governor Kathy Hochul today celebrated the opening of the Roswell Park GMP Engineering and Cell Manufacturing Facility, New York’s first cell and gene therapy hub, located at Roswell Park Comprehensive Cancer Center in Buffalo. The $98 million facility will create new jobs, help to support the research and development of life-saving cell and gene therapies at Roswell, significantly grow its well-established research capabilities, and establish Roswell as one of the premier cell therapy discovery and development institutions in the nation. The expansion also realizes Governor Hochul’s 2023 State of the State commitment to bolster the state’s leadership in the fast-growing CGT sector through establishment of an Upstate cell and gene therapy hub to catalyze its growth in western NY. The GEM facility meets U.S. FDA Good Manufacturing Practice standards for manufacture of clinical cell therapy products, positioning the Roswell Park team to be a multifaceted resource for patients, care teams
Breakthrough in treatment approach showing promise in the fight against glioblastoma, the deadliest and most aggressive type of brain cancer
Mayo Clinic announces the results of an innovative treatment approach that may offer improvement in overall survival in older patients with newly diagnosed glioblastoma while maintaining quality of life. Glioblastoma is the most lethal type of primary brain cancer due to its aggressive nature and its treatment-resistant characteristics. It is the most common form of primary brain cancer.
UW researchers find previously unknown links between microbial bile acids and the risk of colon cancer
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk — in opposite directions — for developing colon cancer.
Memorial Sloan Kettering Physician-Scientists Develop Innovative Multimodal Machine Learning Model That Improves Prediction of Metastatic Breast Cancer Treatment Options
New research presented during the 2024 San Antonio Breast Cancer Symposium (SABCS) reveals a new machine learning model that could change the way metastatic breast cancer is treated in the future. By combining clinical and genomic data, physician-scientists from Memorial Sloan Kettering Cancer Center (MSK) developed a tool that could help improve predictions of how people with hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer respond to CDK4/6 inhibitors, a class of oral medications that control cell division and are often prescribed in combination with hormone therapy to treat this subset of patients.
Generic platinum chemotherapy shortages did not increase deaths
An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023.
UChicago Medicine receives $2.8 million to empower underrepresented students in cancer research
The federally funded pathway programs strive to increase diversity and equity in the cancer research field, a key strategy to reduce health disparities in the Chicagoland area and across the country.
Light-induced gene therapy disables cancer cells’ energy center
Researchers are shining a light on cancer cells’ energy centers – literally – to damage these power sources and trigger widespread cancer cell death.
AI shaping the future of breast cancer risk prediction
A new publication by a national collective of researchers has highlighted the potential for the use of artificial intelligence (AI) in identifying women with increased breast cancer risk. The piece, published in Trends in Cancer, explores how AI can help clinicians to better identify features on a mammogram that indicate a high risk of developing breast cancer.
New Study Shows Mobile Mammography Reach is Highest in Underserved Groups with Low Breast Cancer Screening Adherence
A recent study by the Harvey L. Neiman Health Policy Institute demonstrates that mobile mammography is generally used by women otherwise unlikely to be screened, and thus is complementary to facility-based mammography rather than a substitute for it. Hence, mobile mammography could feasibly increase breast cancer screening rates, especially in traditionally underserved communities. This study, published in Clinical Breast Cancer, was based on 2.6 million women with Medicare fee-for-service insurance during the 2004-2021 period.
Discovery of Gene Linked to High-Altitude Adaptation May Transform Blood Cancer Care
Huntsman Cancer Institute researchers have identified a gene variant found in a high-altitude Andean population that may predict severity of diseases and responses to treatments for patients with certain types of blood cancer.
UTSW Research: Python guts, emergency room visits, and more
Regeneration insights from snake intestines / Understanding why cancer patients visit the ED / How burr holes affect transcranial direct current stimulation
Roswell Park Team Identifies Factors That Boost Effectiveness of Immunotherapy in Recurrent Ovarian Cancer
A study led by Roswell Park provides new insight into the complex interactions of the “tumor-immune-gut axis,” and its role in influencing immunotherapy responses in patients with recurrent ovarian cancer. Newly published in Nature Communications, the findings emphasize the role of the patient’s microbiome — the collection of microorganisms in the body —and lay the groundwork for future clinical trials aimed at improving treatment outcomes.
Social Risks Impede Cancer Screening, Even with Access to Care
Researchers at UC San Diego and collaborating organizations have revealed disparities in cancer screening rates for individuals with social risks, even when patients have regular access to care through a community health center.
Brain tumors hijack circadian clock to grow
New research from Washington University in St. Louis shows that glioblastoma has an internal clock and syncs its daily rhythms to match — and take advantage of — the rhythms of its host. In this way, brain tumors grow in response to the host’s daily release of steroid hormones like cortisol.
How a New Test Is Transforming Care for Retinoblastoma
In 2017, a Children’s Hospital Los Angeles team led by Jesse Berry, MD, pioneered the development of the first liquid biopsy for retinoblastoma, the most common childhood eye cancer. But while the biopsy information—taken from the aqueous humor fluid in the front of the eye—could be studied in the lab, it wasn’t yet able to be applied to patient care.
ACS Study Finds Early-Onset Colorectal Cancer Cases Surge Globally
A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease. In 14 countries, including the United States, rates are increasing in young adults while stabilizing in those 50 years and older. The research is published today in the journal The Lancet Oncology.
Innovative surgery preserves limb growth for childhood bone cancer patients
Arlette Chavez was a typical 3-year-old who loved jumping on the bed, riding her bike, and playing tag, said her mother, Lesly Rivera. When this active preschooler started complaining of pain in her left arm, Ms. Rivera and her husband, Carlos Chavez, weren’t overly concerned – it was probably a minor injury, they reasoned. But when an X-ray revealed a tumor on her left humerus, the bone that runs from the shoulder to the elbow, a biopsy soon confirmed that Arlette had a rare bone and soft tissue cancer called Ewing’s sarcoma. It is diagnosed in only about 200 children and teens each year in the U.S., according to the American Cancer Society.
Esophageal cancer: global burden intensifies, calls for urgent action
A critical study sheds light on the growing global burden of esophageal cancer, outlining its significant impact and the imperative to identify the driving factors behind its increasing prevalence. This research presents a detailed analysis of the disease’s incidence, mortality, disability-adjusted life years (DALYs) rates, and attributable risk factors, providing essential insights for the development of strategic cancer control measures on a global scale.
Fighting prostate cancer, from farm to table, at MSU
With a nod to bringing local, fresh ingredients directly to our dinner plates, Michigan State University researchers will soon be applying their own farm-to-table approach to the fight against prostate cancer. From therapeutic ingredient production to research and testing — it’s all happening at MSU.
Research shows new treatment could delay cancer progression in patients with high-risk smoldering multiple myeloma
A new treatment is showing promise for people with high-risk smoldering multiple myeloma (SMM). This precancerous condition can progress to active multiple myeloma, a type of blood cancer. High-risk SMM carries a higher likelihood of progression.
The Wistar Institute Receives Two Biomedical Research Grants from the V Foundation for Cancer Research
Wistar Institute assistant professors Nan Zhang, Ph.D., and Noam Auslander Ph.D., have both received independent funding totaling $1.2 million over the next three years for cancer research projects from the V Foundation for Cancer Research.
Two UC Irvine researchers named fellows by National Academy of Inventors
The National Academy of Inventors has named two University of California, Irvine researchers as fellows. Hamid Jafarkhani, Chancellor’s Professor of electrical engineering & computer science, was recognized for his pioneering contributions to signal processing for multi-antenna wireless communications systems.
Geriatric Surgery Verification Program Can Improve Outcomes for Older Cancer Patients in Community Hospitals
Implementing the American College of Surgeons (ACS) Geriatric Surgery Verification (GSV) program leads to better postoperative outcomes and preserves independence in older cancer patients undergoing major abdominal procedures, according to a new study published in the Journal of the American College of Surgeons (JACS).
ASH: Triplet combination regimens demonstrate high response rates in multiple leukemias
Three clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated significant positive results from novel triplet therapies in the treatment of relapsed or refractory and newly diagnosed leukemias. The results were presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition. More information on all ASH Annual Meeting content from MD Anderson can be found at MDAnderson.org/ASH.
Could Venetoclax Improve Outcomes of CAR T for Patients with Resistant B-Cell Lymphomas? New Insights at ASH
About a third of patients with diffuse large B cell lymphoma (DLBCL), a fast-growing form of lymphoma, will see their disease advance or recur following treatment. Seeking a new treatment strategy that might boost the effectiveness of existing DLBCL therapies, a team from Roswell Park has been working to understand the underlying mechanisms of the targeted chemotherapy venetoclax. Their findings, to be presented during a talk today at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California, provide strong preclinical evidence that adding venetoclax to standard treatment may improve outcomes in patients with treatment-resistant B-cell lymphomas.
ASH: Monoclonal antibody therapy improves survival in cancer-associated hyper-inflammatory disorder
Adult patients with newly diagnosed malignancy-associated hemophagocytic lymphohistiocytosis (mHLH) – a rare, aggressive hyperinflammatory condition – who were treated with the first-in-class monoclonal antibody, ELA026, experienced a 100% response rate and an improved survival rate at two months, according to researchers from The University of Texas MD Anderson Cancer Center.
Lighting Campus for Hope: A Winter Wonderland of Resilience and Community
More than just a holiday gathering, this free, family-friendly event marked the culmination of a year-long appeal that raised $255,000 to provide 1,350 life-saving cancer screenings in our Borderplex community. Every dollar from event sponsorships will directly support cancer screenings and diagnostics, emphasizing the transformative impact of early detection and care.
New Study Reveals Key Insights on Sarcoma Rates in Military vs. Civilian Men
Researchers at the Uniformed Services University of the Health Sciences (USU) have uncovered compelling insights into the incidence of soft tissue sarcomas among U.S. active-duty servicemen, revealing significant age-related differences compared to the general male population. The findings shed light on the interplay between occupational exposures, healthcare access, and cancer risk, paving the way for targeted prevention strategies and future research.
Resistance Training Can Reduce Fatigue, Pain in Multiple Myeloma Patients, Roswell Park Team Shows
Researchers from Roswell Park Comprehensive Cancer Center will present compelling findings showcasing significant benefits of resistance training for patients with multiple myeloma, in a talk at the 66th American Society of Hematology (ASH) Annual Meeting. The study, led by Jens Hillengass, MD, PhD, and Janine Joseph, MS, MBA, presents new evidence documenting that targeted exercise regimens can alleviate fatigue, improve sleep and reduce pain, offering new hope for enhancing quality of life in cancer care.
Multi-center study shows education level, income impact access to stem cell transplantation for acute myeloid leukemia patients
Patients with acute myeloid leukemia who have lower education levels and lower income are less likely to receive a allogeneic hematopoietic stem cell transplant for acute myeloid, however, if they can access the treatment, are equally likely to benefit from transplant as patients with more education and higher income, according to a new study from Fred Hutch Cancer Center presented at the annual meeting of the American Society of Hematology.
New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented during the plenary session at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego on December 8.
Three Sanford Burnham Prebys faculty members ranked among the world’s most influential scientists
Three faculty members at Sanford Burnham Prebys are among the most influential scientists worldwide in the 2024 rankings by the Institute for Scientific Information at Clarivate.
Analyzing multiple mammograms improves breast cancer risk prediction
A new method of analyzing mammograms — developed by researchers at WashU Medicine — identified individuals at high risk of developing breast cancer more accurately than the standard, questionnaire-based method did. The new method, powered by artificial intelligence, could help diagnose cancer earlier and guide recommendations for earlier screening, additional imaging or risk-reducing medications.
Late-breaking abstract at SUO: Novel oncolytic immunotherapy shows promise for patients with bladder cancer
A Mayo Clinic Comprehensive Cancer Center researcher will share findings from a late-breaking abstract at the 2024 Society of Urologic Oncology Annual Meeting. The study demonstrated a potentially effective treatment for patients with bladder cancer who no longer respond to the common therapy, Bacillus Calmette-Guérin (BCG).
3-Year-Old Patient at Johns Hopkins Children’s Center Is Home for the Holidays After Battling Life-Threatening Brain Tumor
Filip Stevic is a “happy, goofy kid” who loves trucks, dinosaurs and books, according to his parents, Sunny and Milos, who live in Nottingham, Maryland. But the family’s holiday season was nearly upended when a golf ball-sized tumor was discovered inside Filip’s head.
Advances in the Molecular Diagnostic Methods for Circular RNA
The author summarized the traditional and emerging methods for circRNA detection as well as the advantages and limitations, and look forward to future research directions.
Research reveals how fructose in diet enhances tumor growth
Dietary fructose promotes tumor growth in animal models of melanoma, breast cancer and cervical cancer. However, fructose does not directly fuel tumors, according to the study published Dec. 4 in the journal Nature. Instead, WashU scientists discovered that the liver converts fructose into usable nutrients for cancer cells, a compelling finding that could open up new avenues for care and treatment of many different types of cancer.
MSK Awards and Appointments November 2024
NEW YORK, December 4, 2024 – Memorial Sloan Kettering Cancer Center (MSK) today announced the following awards and appointments:
Children’s Hospital Los Angeles Experts to Present at 2024 American Society of Hematology Meeting
Children’s Hospital Los Angeles faculty will present their latest research on pediatric blood cancers and diseases at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego.The annual conference—billed as the world’s largest and most comprehensive hematology event—will take place Dec. 7-10. In 2023, ASH attracted more than 32,000 attendees from over 100 countries.