Novel Coronavirus Circulated Undetected Months before First COVID-19 Cases in Wuhan, China

Using molecular dating tools and epidemiological simulations, researchers at UC San Diego School of Medicine estimate that the SARS-CoV-2 virus likely circulated undetected for two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.

Sewage-Handling Robots Help Predict COVID-19 Outbreaks in San Diego

UC San Diego School of Medicine researchers develop an automated process to test city sewage for SARS-CoV-2, allowing them to forecast the region’s COVID-19 caseload one to two weeks ahead of clinical diagnostic reports.

Repurposed Arthritis Drug Did Not Significantly Improve Severe COVID-19 Pneumonia

A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.

NIH Awards UC San Diego $33 Million for Five COVID-19 Diagnostic Projects

UC San Diego was awarded five COVID-19 Rapid Acceleration of Diagnostics (RADx) projects by the National Institutes of Health totaling nearly $33 million, which will fund efforts that range from managing a large data center to expanding testing in disadvantaged communities.

Nobody finds the Alzheimer’s Germ in $1 Million Challenge, but eight researchers split $200K, says Dr. Leslie Norins of Alzheimer’s Germ Quest

There is now keen interest in deeper investigation of infectious agents as the trigger of Alzheimer’s disease

Can Current Smartphone Technology Tell You When a Pandemic Might Come Calling?

UC San Diego researchers find that an optical tool already embedded in many smartphones can accurately diagnose blood-oxygen levels and help monitor respiratory disease in patients, particularly when they are quarantined at home.

Through a $500 Million Partnership with the State of Ohio, JobsOhio and Ohio Development Services Agency, Cleveland Clinic Forms Global Center for Pathogen Research & Human Health

CLEVELAND: As part of the new Cleveland Innovation District announced today by State of Ohio Governor Mike DeWine, Lieutenant Governor Jon Husted, JobsOhio and Ohio Development Services Agency, Cleveland Clinic will significantly expand its global commitment to infectious disease research and translational programs to form the Global Center for Pathogen Research & Human Health.

The new Center will position Ohio as an international leader for research into emerging pathogens and virus-related diseases and will serve as a significant economic catalyst in Northeast Ohio. Funding comes through a $500 million investment from the State of Ohio, JobsOhio and Cleveland Clinic.

5 Things You Must Do While You Wait for the COVID-19 Vaccine

Even as vaccinations against COVID-19 are under way, the virus continues to kill thousands of Americans every day, making it more important than ever to stay safe and be ready in case it strikes you or your family. Here’s what you need to do to prevent and prepare for the novel coronavirus.

Wildfire smoke carry microbes that can cause infectious diseases

Wildfire smoke contains microbes, infectious agents that might cause diseases. In a perspective piece published in Science, researchers at UC Davis Health and the University of Idaho proposed a multidisciplinary approach to study the health impacts of microbes carried by wildfire smokes.

Study Details First Artificial Intelligence Tool to Help Laboratories Rule-Out COVID-19

Hospital-based laboratories and doctors at the front line of the COVID-19 pandemic might soon add artificial intelligence to their testing toolkit. A recent study describes the performance of Biocogniv’s new AI-COVID™ software, which showed high accuracy in predicting the probability of COVID-19 infection using routine blood tests, which can help hospitals reduce the number of patients referred for scarce PCR testing.

George Washington University Public Health/Medical Experts Available for Media Interviews on the COVID-19 Pandemic

Public health experts predict the United States may be headed for thousands of new COVID-19 cases and deaths this winter, a surge that is already straining health care systems around the country. The George Washington University has the following experts…

CHOP Researchers Find Elevated Biomarker Related to Blood Vessel Damage in All Children with SARS-CoV-2 Regardless of Disease Severity

Researchers at Children’s Hospital of Philadelphia (CHOP) have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19. They also found that a high proportion of children with SARS-CoV-2 infection met clinical and diagnostic criteria for thrombotic microangiopathy (TMA). TMA is a syndrome that involves clotting in the small blood vessels and has been identified as a potential cause for severe manifestations of COVID-19 in adults.

Tip Sheet: Celebrate holidays safely, COVID-19 vaccines, challenges in HIV vaccine trials — and new insights on evolution

SEATTLE – Dec. 2, 2020 – Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.If you’re following the American Society of Hematology’s annual meeting (virtual, Dec. 5-8), see our media tip sheet highlighting Fred Hutch presentations and activities, including those by current ASH president Dr.

IDSA, AAN, AND ACR RELEASE GUIDELINES FOR PREVENTION, DIAGNOSIS, AND TREATMENT OF LYME DISEASE

New evidence-based clinical practice guidelines for the prevention, diagnosis, and treatment of Lyme disease have been developed by a multidisciplinary panel led by the Infectious Diseases Society of America, the American Academy of Neurology, and the American College of Rheumatology. Representatives from an additional 12 medical specialties and patients also served on the panel.

Q&A with Clinical Trial Investigator at UC San Diego Health on How a Century-old Treatment May Prevent COVID-19 in Persons After Exposure

Most media and public attention during the pandemic has focused upon efforts to develop an effective vaccine to prevent COVID-19, which is caused by the novel coronavirus SARS-CoV-2. Some attention has been paid to investigational therapeutics for treating infected patients,…

Study: COVID-19 Infection Combined with Blood Clots Worsen Patient Outcomes

While respiratory issues continue to be the most common symptom of a COVID-19 infection, new research indicates the disease could also be associated with an increased tendency of the blood to clot, leading to a higher risk of death from COVID-19.

Testing Wastewater for COVID-19

UNLV researcher Edwin Oh and colleagues have implemented wastewater surveillance programs to screen samples for the presence of COVID-19 and to extract the RNA from the SARS-COV-2 virus to find targets that make vaccines more effective.

Experts Issue Recommendations for Equitable Distribution of COVID-19 Vaccine

A group of vaccine experts led by Children’s Hospital of Philadelphia (CHOP) has published recommendations to ensure equitable distribution of a COVID-19 vaccine when it becomes available. The framework, published today in Heath Affairs, focuses on five principles the authors believe would strengthen the current immunization delivery system to ensure equitable access to everyone for whom vaccination is recommended.

Rush University Medical Center Surpasses 100,000 COVID-19 Tests

Throughout the COVID-19 pandemic, Rush University Medical Center has been a leader in the Chicago area in developing, expanding and evolving testing efforts. On Friday, Nov. 13, the Medical Center performed its 100,000th test for COVID-19.

Infection by Confection: COVID-19 and the Risk of Trick-or-Treating

Researchers determined that COVID-19 transmission risk via Halloween candies is low, even when they are handled by infected people, but handwashing and disinfecting collected sweets reduces risk even further.

Safely Celebrate the Holidays During COVID-19

Families gathered around the table for hours to share food, conversation and laughter — all the ingredients for a joyous holiday — and the spread of COVID-19. Rush infectious disease specialists and a child psychologist share facts and tips for enjoying the holidays safely.

Story Tips From Johns Hopkins Experts On COVID-19

Johns Hopkins Medicine has launched a new Spanish-language COVID-19 resources portal. This one-stop shop for information in Spanish offers COVID-19 testing sites, information about telemedicine and communicating with health care providers, social distancing tips and resources for children, among other helpful links. The mobile-friendly portal serves community members, patients, faculty and staff members as well as students who need COVID-19 resources and information in Spanish.

Protein that Keeps Immune System from Freaking Out Could Form Basis for New Therapeutics

Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction and supports a mechanism critical for survival in mouse models of sepsis and colitis, according to a UC San Diego study.

HIV Up Close: Unprecedented View of Virus Reveals Essential Steps for Causing AIDS

Accomplishing a feat that had been a pipe dream for decades, scientists at University of Utah Health and University of Virginia have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome). Doing so has provided up-close access to the virus—which is otherwise obstructed from view deep within the cell—and enabled identification of essential components that HIV needs to replicate within its human host. The research publishes in the journal, Cell.

Story Tips From Johns Hopkins Experts On COVID-19

Johns Hopkins Medicine biomedical engineering student Christopher Shallal developed an initiative to keep health care teams safe by galvanizing community members to use 3D printers to make face shields. His mentors on the project were Elizabeth Logsdon, Ph.D., and Warren Grayson, Ph.D.

Chicago Center for HIV Elimination awarded $5 million for community COVID-19 testing and prevention

The Chicago Center for HIV Elimination, housed at the University of Chicago, has been awarded $5 million over two years through the National Institute of Health’s (NIH) RADx Underserved Populations program to support a COVID-19 testing project to engage two disenfranchised populations.