The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Tag: Breast Cancer
Lifestyle Behaviors and Needs After Breast Cancer Diagnosis: A Qualitative Assessment
Abstract Purpose: There is a need to gain a deeper understanding of facilitators and barriers involving lifestyle behaviors among newly diagnosed breast cancer patients. Design: Research team explored influences (e.g., social, cultural, environmental) for healthy lifestyle behaviors (nutrition, physical activity (PA),…
Loyola Medicine Offers Free Cancer Screenings for Women at 10th Annual See, Test and Treat® Event
On Saturday, August 17, 2024, qualified women who make an appointment can receive free cervical and breast cancer screenings as part of Loyola Medicine’s 10th Annual See, Test and Treat® event. This annual event will be held at the Loyola Outpatient Center, 2160 S. First Ave., Maywood, Illinois.
Many breast cancer survivors do not receive genetic testing, despite being eligible
As cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual’s tumor, a new study from the University of Michigan Health Rogel Cancer Center finds that many breast cancer survivors who meet criteria for genetic counseling and testing are not receiving it.
Survey finds women in their 40s may choose to delay mammography when informed about the benefits and harms
A nationally representative U.S. survey found women in their 40s may decide to start mammography at an older age when informed about the benefits and potential harms of breast cancer screening, including overdiagnosis and the risk for a false positive result.
MD Anderson Research Highlights for July 11, 2024
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Antibody-Drug Conjugate Highly Effective in Preventing Recurrence in Patients with Early Stage HER2+ Breast Cancer, Trial Finds
• 97% of HER2+, early-stage patients treated with trastuzumab emtansine (T-DM1) were free of cancer recurrence five years after treatment
• Prognostic test (HER2DX) shown helpful in identifying patients at greatest risk for recurrence
Chemotherapy disrupts gut microbiome in patients with breast cancer
“For the first time ever, our Intelligut Study found that the gut microbiome has been implicated in cognitive side effects of chemotherapy in humans,” said senior author Leah Pyter, associate professor of psychiatry and neuroscience with The Ohio State University Wexner Medical Center and College of Medicine.
Tai Chi reduces risk of inflammatory disease, treats insomnia among breast cancer survivors
New research led by UCLA Health confirms that both Tai Chi and cognitive behavioral therapy can reduce insomnia in breast cancer survivors but also may provide additional health benefits by reducing inflammation and bolstering anti-viral defenses.
The Harvey L. Neiman Health Policy Institute Launches Cancer Equity Compass
The Harvey L. Neiman Health Policy Institute announces the public launch of a new online tool that reveals the overlap between cancer disparities and social determinants of health (SDOH) using advanced heat maps of U.S. counties. The Cancer Equity Compass can identify high-opportunity targets for policies and programs to achieve equitable health outcomes in underserved populations.
Statement on the Kansas State Employees Health Care Commission’s Decision to Increase Access to Breast Imaging
Kansas State Employees Health Care Commission voted unanimously to eliminate the out-of-pocket costs for diagnostic and supplemental imaging for Kansas state employees with an effective date of January 1, 2024.
Xylyx Bio Awarded $2.26M NIH SBIR Grant from National Cancer Institute
Award supports development of a pre-clinical cell-based assay platform to help
scientists discover and test drug candidates for metastatic breast cancer
Statement on Passage of Legislation Increasing Funding for Colorado’s Breast and Cervical Cancer Screening Program
Susan G. Komen®, the world’s leading breast cancer organization, today issued the following statement on the passage of SB 24-086, which provides critical funding for the Women’s Wellness Connection (WWC), Colorado’s breast and cervical cancer screening program.
Introduction of Breast Imaging Legislation Will Benefit Thousands of Ohioans
Breast imaging legislation in Ohio will save thousands of lives.
How tumor stiffness alters immune cell behavior to escape destruction
Researchers at Sanford Burnham Prebys, with collaborators, illuminate how the fibrotic tumor microenvironment creates an inhospitable milieu for anti-tumor immunity, not just by creating a physical barrier but through metabolic changes that suppress the anti-tumor function of responding immune cells.
Early menopause linked to greater risk for breast, and possibly ovarian cancer
Some women who experience menopause early—before age 40—have an increased risk for developing breast and ovarian cancer, according to research being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
High insulin levels contribute to worse outcomes for Black women with aggressive form of breast cancer
High insulin levels contribute to worse outcomes for Black women compared to white women who have an aggressive form of breast cancer called triple-negative breast cancer, according to a study presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.
Almost 20% of breast cancer survivors may experience excess weight gain
Almost one out of five breast cancer survivors may experience weight gain of more than 10%, suggests a study presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. A number of factors are associated with excessive weight gain, the researchers found.
Study Reveals Worse Clinical Outcomes in Breast Cancer Patients Who Reported Higher Pain and Stress
Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).
Study Shows Polygenic Risk Score (PGS) Could Predict Breast Cancer Survival Outcomes
Data from a large prospective cohort study reveal that a polygenic risk score has the potential to predict survival outcomes in patients with breast cancer.
Promising New Treatment for Patients with HR+ HER-2 Negative Metastatic Breast Cancer
New research from Yale Cancer Center reveals first-of-its-kind data from a phase I study in patients with hormone receptor positive HER2-negative metastatic breast cancer. The results, which assess the safety and efficacy of a treatment known as PF-07248144, offer new hope for treating this aggressive type of breast cancer.
A phase 1 dose expansion study of a first-in-class KAT6 inhibitor (PF-07248144) in patients with advanced or metastatic ER+ HER2− breast cancer.
For this presentation at ASCO 2024, please email the media contact for more information.
Trilaciclib use for prevention of hematological adverse events in chemotherapy: A meta-analysis of real-world studies and clinical trials
Background: Trilaciclib, a cyclin-dependent kinase (CDK)-4 and -6 inhibitor, is the only FDA-approved agent that preemptively protects hematopoietic stem cells from chemotherapy-induced myelosuppression (CIM) without compromising efficacy. It transiently arrests hematopoietic stem cells in the G1 phase, thus temporarily blocking progression…
Get Ready for ASCO 2024 Annual Meeting
ASCO, the largest event in cancer research, is approaching on May 31st. This year’s meeting promises to be particularly groundbreaking, with new findings and innovations that could revolutionize cancer treatment.
Donepezil Does Not Improve Chemotherapy-Related Cognitive Impairment
Researchers at Wake Forest University School of Medicine conducted a Phase III randomized, placebo-controlled trial to test donepezil, a cognitive-enhancing medicine used in the treatment of Alzheimer’s disease. The research team found that donepezil did not improve memory or other cognitive functions in survivors with cancer-related cognitive impairment.
Plant virus treatment shows promise in fighting metastatic cancers in mice
An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego.
Lifestyle interventions with dietary strategies after breast cancer diagnosis: a systematic review
Purpose: Obesity can increase mortality and morbidity in breast cancer survivors. Healthy lifestyle factors such as diet can help manage weight in this population. This systematic review examined lifestyle interventions with dietary strategies for breast cancer survivors and their effect on…
This Mother’s Day – A NJ Mother & Daughter Are Grateful to Survive Breast Cancer – Together
Merlise Diaz, 48, and her daughter, Leslie Grullon, 32, were diagnosed with triple negative breast cancer and HER2-positive breast cancer three years apart and have no other confirmed family history of the disease. When Diaz received her stage two diagnosis…
MD Anderson Research Highlights for May 8, 2024
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Sylvester Researchers Develop a Nanoparticle That Can Penetrate the Blood-Brain Barrier
Researchers at Sylvester Comprehensive Cancer Center have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer tumors and brain metastases in one treatment.
New breast cancer screening recommendations aim to address health inequities, especially among Black women
Challenges remain in ensuring equitable access to screening and addressing gaps in evidence regarding supplemental screening modalities and the adoption of artificial intelligence (AI) technologies, notes Joann Elmore, MD, MPH, a professor of medicine at the David Geffen School of Medicine at UCLA in a newly published editorial in JAMA.
ACR statement on final USPSTF breast cancer screening recommendations
The final United States Preventive Services Task Force (USPSTF) Breast Cancer Screening Recommendations, while an improvement over previous guidance, do not go far enough to save more women’s lives. Women at average risk for breast cancer should start annual screening at age 40.
The Aspirin Conundrum: Navigating Negative Results, Age, Aging Dynamics and Equity
A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers from Georgetown University’s Lombardi Comprehensive Cancer Center.
Ferrum Health Expands AI Offerings in Partnership with Radiology Associates of Albuquerque (RAA)
Ferrum Health, the leading artificial intelligence platform for healthcare, is excited to announce that Gleamer’s BoneView is now available to assist clinicians in the detection of bone trauma in Albuquerque, New Mexico.
AI-assisted breast-cancer screening may reduce unnecessary testing
Researchers at Washington University School of Medicine in St. Louis and Whiterabbit.ai showed that AI assistance potentially could improve breast-cancer screening by reducing the number of false positives without missing true positives.
Radiation before mastectomy cuts time delays for reconstructive surgery in breast cancer patients
Researchers at The University of Texas MD Anderson Cancer Center showed that altering the sequence of breast cancer treatment to administer radiation before mastectomy allowed for concurrent breast reconstruction surgery, which reduced the number of operations required, minimized treatment delays and improved patient satisfaction.
Introduction of Legislation to Expand Access to Breast Cancer Treatment for Missourians
Susan G. Komen®, commends Representative Chantelle Nickson-Clark (D-Florissant) for working with Komen to expand eligibility for the MO HealthNet Breast and Cervical Cancer Treatment (BCCT) program, providing increased access to vital breast and cervical cancer treatment services.
Breakthrough in triple negative breast cancer shows optimal timing for immunotherapy
Abstract presented at the European Breast Cancer Conference: “The ALEXANDRA/IMpassion030 trial is the first study to look at the role of chemotherapy with or without atezolizumab post-surgery for early-stage triple-negative breast cancer.” – Dr. McArthur Interviews with study author and…
Susan G. Komen® Urges U.S. House, Senate to Pass Critical Breast Health Legislation After House Committee Vote
Susan G. Komen is urging the U.S. House and Senate to bring the SCREENS for Cancer Act to a floor vote as soon as possible so breast health services are available to those who need them now.
Moncrief Cancer Institute debuts new Mobile Screening Clinic funded by Tarrant County
Moncrief Cancer Institute debuted its new Mobile Screening Clinic prior to the Tarrant County Commissioners Court meeting today. The $1 million, 36-foot cancer screening clinic was funded by Tarrant County through a three-year, $9 million grant awarded to Moncrief Cancer Institute in 2022. Part of the federal funding Tarrant County received through the American Rescue Plan Act (ARPA), the grant enabled Moncrief to expand its comprehensive cancer screening program to more underserved residents in Tarrant County.
How Olivia Munn’s doctor knew she was at risk for breast cancer
Deborah Farr, M.D. is a surgical oncologist who specializes in treating breast cancer. When Dr. Farr heard about Olivia Munn’s diagnosis, she immediately knew what tool gave her the lifesaving information that she needed. “The breast cancer risk assessment tool…
Breast Cancer Diagnoses Plummeted During First Year of Pandemic
There was a 15-20% decrease in newly diagnosed breast cancer cases reported to American College of Surgeons Commission on Cancer sites in 2020 compared to 2019.
¿La soja aumenta el riesgo de cáncer de mama?
Ha generado varios debates. ¿Hay alguna conexión entre la soja y el cáncer de mama? La soja contiene isoflavonas, que son los estrógenos vegetales. Se han relacionado los niveles altos de estrógeno con un mayor riesgo de cáncer de mama. Sin embargo, hay estudios que demuestran que los productos de soja no contienen niveles de estrógeno lo suficientemente altos como para aumentar las probabilidades de desarrollar cáncer de mama.
Researchers Perform Anatomical Dissection to Identify Sensory Nerves for Improved Cancer Treatment
Researchers from the London Health Sciences Centre use anatomical dissection to identify undocumented nerve pathways for the most diagnosed cancer worldwide.
Study Identifies Successful Methods to Recruit South Asian Women for Breast Cancer Research
Rutgers Health experts, conducting research during the COVID-19 pandemic, found that radio is an effective recruitment tool
Launch of a pioneering translational research programme in Europe
– The TRIP initiative establishes three new joint laboratories that bring together fundamental biomedical research and clinical research with the aim of accelerating the delivery of results to patients.
– TRIP will focus on emerging fields such as immuno-oncology, inflammation, and cellular senescence.
NCCN Updates Treatment Recommendations for Breast, Colorectal, Lung, and other Cancer Types Based on Emerging Evidence
Recent NCCN Guidelines updates—along with the supporting evidence—will be presented during the NCCN 2024 Annual Conference held in Orlando, Florida April 5-7, and simultaneously online. Visit NCCN.org/conference to learn more and register.
Study Underscores Social Factors of Low Breast Cancer Screening in the U.S.
To identify major social factors hindering breast cancer screening in U.S. women aged 40 and older, researchers focused on race/ethnicity, employment, education, food security, insurance status, housing and access to quality health care. Access to health care emerged as a statistically significant theme (61 percent) and insurance status was the most reported sub-categorical factor. Language was the third highest issue, highlighting its significance as an influential factor of screening behavior. Race/ethnicity, sex/gender and sexual orientation were additional factors reported.
National Breast Cancer Foundation Gives Grant to Help Breast Care Center Patients at Texas Tech Physicians of El Paso
In addition to assisting with access to care, such as transportation and general needs like groceries, the grant will allow the Breast Care Center to screen for mental and emotional distress using tablets. Currently, patients participate in an online distress screening survey that prompts questions about financial and psychosocial stressors in a patient’s life.
The Wistar Institute Announces New Caspar Wistar Fellow, Dr. Irene Bertolini
Wistar Institute is pleased to announce the recruitment of Irene Bertolini, Ph.D., to pursue research in breast and brain cancers.