AACR 2023: Ohio State experts share new findings on immuno-oncology, ‘smart-drugs,’ obesity-related endometrial cancers and other research topics

New smart-drug treatment options for pancreatic cancer, immuno-oncology treatments and real-time immune-monitoring strategies are among the research topics to be presented by investigators at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) at the American Association for Cancer Research (AACR) annual meeting held April 14-19 at the Orange County Convention Center in Orlando, Florida.

Living Beyond Breast Cancer to Host 17th Annual Thriving Together Conference on Metastatic Breast Cancer April 28–30, 2023 in Philadelphia

Living Beyond Breast Cancer’s Thriving Together 2023 Conference on Metastatic Breast Cancer, the nation’s premier and longest-running conference for people affected by stage IV breast cancer, will be held April 28–30, 2023 at the Hilton Philadelphia at Penn’s Landing as well as virtually.

MD Anderson Research Highlights for March 8, 2023

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

Breast cancer disparity equally impacted by social determinants of health, tumor biology

Researchers calculated the effect of social determinants of health — specifically neighborhood disadvantage and insurance status — on mortality and found they accounted for 19% of the disparity. They also calculated the effect of biological characteristics of the tumors by looking at data from genomic laboratory test results, which were used to anticipate tumor response to chemotherapy and likelihood of recurrence. They found tumor biology accounted for 20% of the disparity.

Introduction of Diagnostic and Supplemental Imaging Legislation Would Benefit Thousands of Marylanders

Susan G. Komen®, the world’s leading breast cancer organization, applauds Senator Pamela Beidle (D-Anne Arundel) and Delegate Sheree Sample-Hughes (D-Dorchester) for working with Komen to introduce legislation that would remove financial barriers to imaging that can rule out breast cancer or confirm the need for a biopsy. In 2023, more than 5,760 people will be diagnosed with breast cancer and more than 850 will die of the disease in Maryland alone.

Legislation Introduced In Oklahoma Would Increase Access to Treatments for Metastatic Cancer Patients

Susan G. Komen®, the world’s leading breast cancer organization, applauds Representative Nicole Miller (R-Edmond) for working with Komen to introduce legislation that would prohibit step therapy requirements for metastatic cancer patients. Komen believes patients and their physicians should be able to make treatment decisions based on the particular needs of each patient without the burden of harmful insurer policies.

MD Anderson Research Highlights for February 1, 2023

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

Study finds large gap in breast cancer treatment recommendations for patients aged 70 vs 69

Age-based heuristics can lead to large differences in breast cancer treatment based on small differences in chronologic age, according to a new analysis of more than 500,000 patient records. Patients aged 70 were nearly twice as likely to be passed over for standard-of-care radiation as those aged 69. There were no similar gaps between other age pairs. The study is among the first to demonstrate an age cutoff heuristic in oncology.

Expert Available for Comment on Black Women, Breast Cancer and Clinical Trials

While there has been an overall decline in breast cancer deaths over the last 30 years, there is a persistent and significant mortality gap between Black women and white women. Black women are also disproportionately affected by more aggressive subtypes of…

Breast Cancer Risk Calculator Can Assess Risk of Advanced Breast Cancer

Breast cancer is now the leading cause of global cancer incidence among women but determining who will develop breast cancer is still a challenge for the medical community. A new tool, developed by researchers from UCSF and several other medical institutions, helps to calculate risk for those who may develop advanced breast cancer that goes undiagnosed despite regular screenings.

Mayo Clinic researchers identify women with twice the risk of cancer in both breasts

Women with cancer in one breast may be at higher risk of developing cancer in the opposite breast if they are carriers of specific genetic changes that predispose them to develop breast cancer, according to a study led by the Mayo Clinic Comprehensive Cancer Center. The findings, published in the Journal of Clinical Oncology, will help personalize approaches to breast cancer screening and risk factors, study authors say.

MD Anderson Research Highlights: SABCS 2022 Special Edition

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into basic, translational and clinical cancer research from MD Anderson experts. This special edition features breast cancer presentations at the 2022 San Antonio Breast Cancer Symposium (SABCS) focused on the combination of everolimus and hormone therapy, a new driver for brain metastases in inflammatory breast cancer, improving treatment for men with breast cancer, and a new understanding of the importance of HER2 expression for patients with early-stage triple-negative breast cancers.

Women with Elevated Breast Cancer Risk Could See Mortality Benefit from Estrogen-Blocking Drugs

While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developing new breast cancers, a new computer modeling study led by researchers at Georgetown Lombardi Comprehensive Cancer Center and colleagues showed that these treatments could also reduce the risk of dying from the disease in women who are at high risk.

Study in mice suggests that expression of estrogen-related gene can impact post-menopausal breast cancer risk and prevention strategies

In a study using a first-of-its kind mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues have determined that over-expression, or switching on of the Esr1 gene, could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women.

Breast Cancer Survivor Uses Personal and Professional Experience to Help Others

Rensselaer Polytechnic Institute Professor of Computer Science, Cognitive Science, and Industrial and Systems Engineering Deborah McGuinness was diagnosed with breast cancer nearly 10 years ago. Her treatments were emotionally and physically challenging: McGuinness endured six months of chemotherapy, 33 radiation treatments, and four surgeries before emerging with current “no evidence of disease” status.

Breast Cancer Research Foundation Renews Support for Mount Sinai Research on Triple-Negative Breast Cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer. The latest installment of $225,000 brings the total to almost $2 million over the past nine years. It will fund research into the immune microenvironment of triple-negative breast cancer in order to identify new strategies to enhance cancer-fighting immune responses for this aggressive breast cancer, which traditionally has few options for treatment.

Spreading hope through humor — Markey Cancer patient, comedian shares her story

As a stand-up comedian, Debra Faulk is an expert at transforming the most difficult and uncomfortable moments of her life into something that lifts others. Active in the local comedy scene, the 54-year-old Lexington native uses standup as a platform to shine a light on serious health issues, with much of her routine inspired by her family’s experiences: one sister dealt with intellectual disabilities while another had breast cancer, her brother served in Desert Storm and came back with PTSD, her father had dementia, and her mother was on dialysis.

MD Anderson Research Highlights for October 19, 2022

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include a combination approach to overcome PARP inhibitor resistance in breast and ovarian cancers, a deeper understanding of STAT3 mutations as drivers of disease progression, insights into the “obesity paradox” in men with advanced melanoma, a prognostic model for rapidly progressing vestibular schwannoma, and a role for cellular trafficking proteins in creating a metastasis-promoting lung cancer microenvironment.

FSU faculty available to speak for Breast Cancer Awareness Month

By: Bill Wellock | Published: October 10, 2022 | 1:11 pm | SHARE: More than 264,000 people are diagnosed with breast cancer every year in the United States. Although deaths from breast cancer have declined over time, it remains the second-leading cause of cancer death among women.October is Breast Cancer Awareness Month, an opportunity to focus on the impact of this disease.