In addition to its predictive value, the discovery could lead to new treatments to prevent deadly cytokine storms. It also may help explain why diabetes contributes to worse outcomes in patients with COVID-19.
Tag: Diabetes
Ohio State Study: Exercise Increases Benefits Of Breastmilk For Babies
A new study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine finds even moderate exercise during pregnancy increases a compound in breast milk that reduces a baby’s lifelong risks of serious health issues such as diabetes, obesity and heart disease.
The Association of Diabetes Care & Education Specialists Foundation and Certification Board for Diabetes Care and Education announce mentored postdoctoral fellowship in integrated diabetes management
Diabetes organizations collaborate to offer mentored fellowship in integrated diabetes management. Applications must be submitted by July 31, 2020.
New technique allows scientists to measure mitochondrial respiration in frozen tissue
UCLA scientists have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples. By speeding up research, investigators hope to accelerate the diagnosis of people living with mitochondrial diseases and secondary disorders in which mitochondria play a key role, including diseases related to aging, metabolism and the heart.
2020 Warren Alpert Prize Recognizes Seminal Discoveries in Metabolism
The 2020 Warren Alpert Foundation Prize has been awarded to a trio of researchers for seminal discoveries about the function of key intestinal hormones, their effects on metabolism and the subsequent design of treatments for type 2 diabetes, obesity and short bowel syndrome.
Registration Opens for the Virtual ADCES 2020 Annual Conference
Access the latest in diabetes, prediabetes and cardiometabolic care at the Virtual ADCES 2020 Annual Conference from Thursday, Aug. 13 to Sunday, Aug. 16.
Continuous Glucose Monitoring Reduces Hypoglycemia in Older Adults with Type 1 Diabetes
Results from a six-month, multi-site clinical trial called the Wireless Innovation for Seniors with Diabetes Mellitus (WISDM) Study Group have been published by the Journal of the American Medical Association (JAMA).
Blocking brain signals detected in the kidney could help unlock future treatments for kidney failure, heart disease, and stroke
Scientists have discovered an important cell signalling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.
Study: National calorie menu labeling law will add years of healthy living, save billions
The national law requiring calorie labeling on menus at large chain restaurants is estimated to prevent tens of thousands of new heart disease and type 2 diabetes cases—and save thousands of lives—in just five years, according to a new study that estimates the law’s impact.
Health care organizations issue joint framework to increase utilization of diabetes self-management education and support
Seven leading diabetes organizations issued a consensus report today highlighting the value of diabetes self-management education and support (DSMES) services as part of comprehensive diabetes medical care. The report provides compelling evidence for the need for increased utilization of DSMES, four key times that DSMES is most beneficial, and specific recommendations for both clinicians and health systems to increase access to and participation in DSMES services.
Hospitalized COVID-19 patients with diabetes represent more than 20 percent of ICU population
The COVID-19 pandemic presents new challenges for clinicians caring for infected patients with diabetes, according to new guidance published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Leaders Call for ‘Moonshot’ on Nutrition Research
Leading nutrition and food policy experts outline a bold case for strengthening federal nutrition research in a live interactive session as part of NUTRITION 2020 LIVE ONLINE, a virtual conference hosted by the American Society for Nutrition (ASN).
Swelling of Tissues Drives Immune System Activity, UCLA Researchers Find
A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.
Eating Whole Grains Could Help Lower Diabetes Risk
A new analysis of more than 200,000 people found that eating high-quality carbohydrates, such as whole grains, was associated with a lower risk for type 2 diabetes.
People with Type 1 Diabetes Spend About $2,500 a Year in Health Care Costs
Adults and children with type 1 diabetes will spend an average of $2,500 a year out-of-pocket for health care – but insulin isn’t always the biggest expense – new research suggests
Sea Snail, Human Insulin Hybrid Could Lead to Better Diabetes Treatments Sea Snail, Human Insulin Hybrid Could Lead to Better Diabetes Treatments Sea Snail, Human Insulin Hybrid Could Lead to Better Diabetes Treatments Sea Snail, Human Insul
Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world’s smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails. The finding, based on animal studies, could jumpstart the development of insulin treatments capable of improving the lives of those with diabetes.
Featured research from NUTRITION 2020 LIVE ONLINE
Press materials are now available for NUTRITION 2020 LIVE ONLINE, a dynamic virtual event showcasing new research findings and timely discussions on food and nutrition. The online meeting will be held June 1–4, 2020.
First map of proinsulin’s “social network” reveals new drug target for type 2 diabetes
Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study, published in Diabetes, also revealed one protein—called PRDX4—that may be essential for proinsulin folding and insulin production. The research suggests that boosting PRDX4 levels may be a novel therapeutic approach to improving the health of people with diabetes.
Blood test could predict diabetes years before it strikes
Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness during pregnancy.
Drug combination could eliminate side effects of once-popular diabetes treatment
A new UT Southwestern study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side effects.
Announcing NUTRITION 2020 LIVE ONLINE
Journalists and bloggers are invited to attend NUTRITION 2020 LIVE ONLINE, a dynamic virtual event showcasing new research findings and timely discussions on food and nutrition. The online meeting will be held June 1–4, 2020.
Patients prefer their consent to share their data and to manage it digitally
A group of patients with diabetes were surveyed on their understanding of the consent process to have their medical data shared with digital platforms offering innovations to the management of their condition.
Insulin Resistance Contributes to Racial Disparities in Breast Cancer Prognosis in U.S. Women, Mount Sinai Researchers Reveal
New study identifies that differences in insulin resistance can explain in part the disparities in breast cancer survival between black and white women
Diabetes Drug May Protect Breastfed Children from Future Metabolic Disorder
A new study suggests that treating a breastfeeding parent with a common diabetes drug may provide male offspring lifelong protection against diabetes and obesity. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism. It was chosen as an APSselect article for May.
First-in-Kind Study Reveals Genetic Markers of Type 2 Diabetes in East Asians
This research, published in Nature, shows how different populations of people share most of the genetic susceptibilities to developing type 2 diabetes but do have some different genetic variations that can make them more or less susceptible to developing the condition.
Diabetes Drug May Protect Breastfed Sons from Future Metabolic Disorder
Article title: Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner Authors: Zach Carlson, Hannah Hafner, Molly Mulcahy, Kaylie Bullock, Allen Zhu, Dave Bridges, Ernesto Bernal-Mizrachi, Brigid Gregg From the authors: “Future…
Heart attack, stroke risk declines among people with diabetes
The rate of heart attacks, strokes and other cardiovascular complications has improved among people with diabetes over the past 20 years, narrowing the gap in cardiovascular mortality rates between individuals with and without diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Older men with sarcopenia are more likely to develop diabetes over time
Older men who have lower lean body mass as they age are more prone to developing diabetes, while similar findings were not found in older women, according to a new study published in Journal of the Endocrine Society.
Wake Forest School of Medicine Receives NIH Diabetes Research Center Grant with Partner Institutions
Wake Forest School of Medicine, in partnership with University of North Carolina School of Medicine (UNC), Duke University School of Medicine and North Carolina Agricultural and Technical State University (NC A&T), has been awarded a $5.7 million Diabetes Research Center grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health (NIH).
High-altitude adaptations connected with lower risk for chronic diseases
High-altitude adaptations in the Himalayas may lower risk for some chronic diseases, according to a research team including faculty from Binghamton University, State University of New York, the University of New Mexico, and the Fudan University School of Life Sciences.
Diabetes reversed in mice with genetically edited stem cells derived from patients
Researchers at Washington University School of Medicine in St. Louis have used induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes, transformed the stem cells into insulin-producing cells, used the CRISPR gene-editing tool to correct a defect that caused a form of diabetes, and implanted the cells into mice to reverse diabetes in the animals.
Impaired Blood Clotting May Explain Higher COVID-19 Risk
A new review suggests that higher-than-normal levels of an enzyme involved in blood clot prevention may be a common risk factor for developing COVID-19—a respiratory disease caused by the novel coronavirus SARS-CoV-2—in some populations. The review is published in Physiological Reviews.
Impaired Immunity, Gene Expression May Explain Higher COVID-19 Risk in People with Diabetes
The behavior of previous coronaviruses together with physiological characteristics of diabetes may help explain why people with diabetes have a higher risk of developing COVID-19, a respiratory disease caused by the novel coronavirus SARS-CoV-2.
Medical teams need to be alert to the extra risks faced by diabetics from COVID-19
Doctors need to pay particular attention to patients with endocrine disorders and diabetes mellitus in relation to COVID-19 infections, say leading endocrinologists.
AADE7 Self-Care Behaviors revised in new guidance from the Association of Diabetes Care & Education Specialists
The framework for the AADE7 Self-Care Behaviors were recently published, highlighting changes in diabetes care and management.
Individuals taking class of steroid medications at high risk for COVID-19
Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Coconut oil reduces features of metabolic syndrome in obese females, animal study finds
Obese females that ate a small amount of coconut oil daily, even as part of a high-fat diet, had decreased features of metabolic syndrome, a cluster of risk factors that raise the chances of developing diabetes, heart disease and stroke, an animal study finds. The study results were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.
Wearable delivery device allows patients with type 2 diabetes to safely use more affordable insulin option
Adults with type 2 diabetes requiring insulin therapy can safely achieve good blood sugar control using regular human insulin (RHI) in a wearable, patch-like insulin delivery device called V-Go®, a new study finds. Results of the randomized controlled study—which was accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society—suggest “a more affordable option” for insulin therapy than newer insulin types, the researchers said.
Artificial intelligence could help predict future diabetes cases
A type of artificial intelligence called machine learning can help predict which patients will develop diabetes, according to an ENDO 2020 abstract that will be published in a special supplemental section of the Journal of the Endocrine Society.
Two types of diabetes drugs similarly effective in reducing heart and kidney disease
Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
Technology use by adults with type 1 diabetes lower among African Americans, Hispanics
Continuous glucose monitor (CGM) and continuous subcutaneous insulin infusion (CSII) devices are known to improve outcomes in patients with type 1 diabetes (T1D), yet African American and Hispanic patients face barriers to the use of these devices, according to results of a small single-center retrospective study. The results of the ENDO 2020 abstract will be published in the Journal of the Endocrine Society.
Loss of gland in eyelids may be a biomarker for elevated blood glucose in diabetes
In patients with diabetes, loss of the gland that helps lubricate the eye may be a sign of elevated blood glucose levels, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The study will be published in the Journal of the Endocrine Society.
Medtronic MiniMed 670G insulin pump allows “excellent” blood glucose control
Patients with type 1 diabetes who use Medtronic’s MiniMedTM 670G insulin pump system are able to maintain blood glucose levels in the targeted range over 71% of the time, according to a study that analyzed some 6 million days of real-world data. Results of the industry-supported study were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental issue of the Journal of the Endocrine Society.
Bariatric surgery before diabetes develops leads to greater weight loss
Obese patients may lose more weight if they undergo bariatric surgery before they develop diabetes, suggests a study accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The research will be published in a special supplemental issue of the Journal of the Endocrine Society.
Better controlled diabetes is associated with preserved cognitive function following stroke
Better glucose control can help people with diabetes who have a common type of stroke to preserve their cognitive function, according to a study accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The abstract will be published in a special supplemental issue of the Journal of the Endocrine Society.
Diabetes care reaches new heights as drone delivers insulin for patient
The international medical team that accomplished the world’s first documented drone delivery of insulin for a patient living in a remote community described the project in an ENDO 2020 abstract that will be published in the Journal of the Endocrine Society.
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW–Madison study shows.
Virtual ENDO 2020 news conferences to highlight advances in technology, thyroid health
Researchers will discuss how artificial intelligence and drones are being incorporated into health care when they share the latest emerging science during the Endocrine Society’s ENDO 2020 virtual news conferences March 30-31.
Reducing Kidney Failure Rate Among Patients with Diabetic Kidney Disease
Now, as part of an effort to reduce the rate of patients with diabetic kidney disease who develop kidney failure, researchers at Penn Medicine are spearheading a collaboration to better understand the progression of DKD and advance research aimed at preserving kidney function in these patients.
For the evaluation and treatment of diabetic eye disease, ultra-wide field imaging techniques cannot be used interchangeably
Diabetic retinopathy can be diagnosed and graded with the use of a newer scanning technology called ultra-wide field (UWF) imaging, a system that generates high-quality pictures showing most of the retina. Research from the Joslin Diabetes Center’s Beetham Eye Institute has now shown that one technique, UFW fluorescein angiography, detects over three times more microaneurysms than UWF color imaging