Exposure to Marijuana in the Womb May Increase Risk of Addiction to Opioids Later in Life, Study Finds

University of Maryland School of Medicine Researchers Identify Neurobiological Changes Leading to Increase Release of the Brain Chemical Dopamine and Its Target Neurons Linked to Addiction-Like Behavior With the increased legalization of recreational cannabis, as many as 1 in 5 pregnant women in the U.S. are now using the drug to help with morning sickness, lower back pain or anxiety.

Study: Online E-Cigarette Retailers Fail to Comply with Sale Regulations

Online e-cigarette retailers are not consistently adhering to laws aimed at preventing the sale of vaping products to minors, including regulations on age verification, shipping methods and flavor restrictions, report researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego.

Brain Imaging of Neuromelanin May be Key to Understanding Extensive Substance Use

A study that used a specialized type of magnetic resonance imaging (MRI), named neuromelanin-sensitive MRI, showed that this type of MRI signal was increased in regions of the midbrain in young adults ages 20 to 24 who had an extensive alcohol and drug use history. The findings are published early online in the American Journal of Psychiatry.

Patients with Alcohol Use Disorder at Risk of Liver Disease May be Less Commonly Referred for Liver Treatment if they are primarily seen for Mental Health Disorders

People with alcohol use disorder (AUD) who are at risk of advanced liver disease are less likely to be referred for liver evaluation and care if they present primarily with alcohol-related mental health issues or a mental health diagnosis, according to a study of referral practices in Virginia’s largest health system. The findings point to the possibility of widespread missed opportunities for treating three conditions that commonly co-occur: AUD, mental health disorders, and liver disease. Recent years have seen notable increases in the USA in alcohol-related deaths, mental health disorders, and hospital admissions relating to alcohol use and concurrent mental health conditions. AUD is a significant cause of liver disease, and both addiction and co-occurring mental illness can be barriers to successful liver treatment. Integrating AUD treatment, mental health care, and hepatology (liver care) is necessary to improve outcomes, but data suggests this approach is not the norm. For the st

National Academy of Medicine Selects FAU for Substance Use, Opioid Crises Collaborative

FAU joins the National Academy of Medicine’s Action Collaborative on Combating Opioid Crises. This pilot project, involving more 80 organizations, aims to enhance coordination and address addiction challenges through collaboration among public, private and nonprofit sectors.

Unveiling the Brain’s Reward Circuitry

A research team – co-led by Penn Nursing – has made a significant breakthrough in understanding the complex neural circuitry underlying reward and addiction by identifying 34 distinct subtypes of medium spiny neurons (MSNs) in the nucleus accumbens (NAc), a key brain region involved in pleasure and motivation. The findings, published in the journal Scientific Reports by Nature, offer insights into the diversity of these neurons and their potential roles in substance use disorders.

UNC Health Researchers Present Preliminary Data on Weight Loss Drugs on Alcohol Addiction

Christian Hendershot, PhD, associate professor of psychiatry and director of the Clinical and Translational Addiction Research Program at the UNC School of Medicine, presented early findings from the first completed randomized controlled trial of semaglutide for reducing alcohol consumption in heavy drinkers.

Stopping a spreading fire: identifying connections between adverse childhood events and substance use disorders

Physical and sexual abuse, having parents who misuse substances, and witnessing violent crime are tragic events that don’t remain locked in a single point in time. Rather, they are termed adverse childhood experiences (ACEs) and 64 percent of American adults who participated in a recent survey reported experiencing at least one ACE prior to turning 18 years old.

Retrospective Study Based on Electronic Health Records Finds Popular Diabetes and Weight-Loss Drugs Associated with Reduction in Incidence and Recurrence of Alcohol-Use Disorder by at Least Half

A new study by researchers at the Case Western Reserve University School of Medicine reveals that the popular diabetes and weight-loss drugs Wegovy and Ozempic are linked to reduced incidence and recurrence of alcohol abuse or dependence.

Expert on rural Appalachia champions coalition building and local knowledge

Research from a West Virginia University scholar of rural Appalachia shows how even the most marginalized communities can assert power and create change when they come together to form coalitions.

A Common Pathway in the Brain That Enables Addictive Drugs to Hijack Natural Reward Processing Has Been Identified by Mount Sinai

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

Bloomberg American Health Initiative at the Johns Hopkins Bloomberg School of Public Health Announces Seventh Cohort of Bloomberg Fellows

The Bloomberg American Health Initiative at the Johns Hopkins Bloomberg School of Public Health announces the 2023 Bloomberg Fellows, each selected from organizations working to improve one of five critical public health challenges facing the country: addiction and overdose, adolescent health, environmental challenges, food systems for health, and violence.

Cannabis use disorder and schizophrenia connection: expert says the drug, “seems to be amplifying some of the consequences that we are seeing”

What: A new study in Psychological Medicine found an association between young men with cannabis use disorder and a higher risk of developing schizophrenia. Furthermore, intense cannabis use may trigger and/or worsen schizophrenia.  Who: Katharine Sperandio, Ph.D., LPC, ACS, NCC, assistant professor of…

IU researchers receive $8.6M NIH grant renewal to study alcohol use, binge drinking

A multi-disciplinary team of Indiana University researchers is focusing their efforts on a growing public health concern: binge and “high-intensity” drinking—extreme drinking behaviors that are increasingly prevalent among college-age adults.

Brain-gut connection may reveal way to prevent cocaine addiction

Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research from the University of Wisconsin–Madison.Cocaine increases levels of a hormone called norepinephrine in users’ intestines, triggering an explosion of growth of proteobacteria, a family of microbes that includes the common and sometimes harmful bacterium E.

Human Cocaine and Heroin Addiction Is Found Tied to Impairments in Specific Brain Circuit Initially Implicated in Animals

Study results suggest the pre-frontal cortex-habenula circuit is potentially amenable for targeted interventions and prevention.

WVU pharmaceutical experts caution ‘one pill can kill’ as new forms of fentanyl become more prevalent

Faculty members with the West Virginia University School of Pharmacy are issuing warnings about the rise of fentanyl in Mountain State communities and elsewhere following the recent seizure of a large amount of “rainbow fentanyl,” potent illegal pills resembling candy, by law enforcement officers in Monongalia County.