English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduThree clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated significant positive results from novel triplet therapies in the treatment of relapsed or refractory and newly diagnosed leukemias. The results were presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition. More information on all ASH Annual Meeting content from MD Anderson can be found at MDAnderson.org/ASH.
Bringing dark comets to light
Where did Earth’s water come from? It’s a fundamental scientific question that has never been answered. In fact, NASA reports that we can only observe and understand 5% of the universe — with a whopping 95% remaining a complete mystery because of unobservable dark matter and dark energy.
Could Venetoclax Improve Outcomes of CAR T for Patients with Resistant B-Cell Lymphomas? New Insights at ASH
About a third of patients with diffuse large B cell lymphoma (DLBCL), a fast-growing form of lymphoma, will see their disease advance or recur following treatment. Seeking a new treatment strategy that might boost the effectiveness of existing DLBCL therapies, a team from Roswell Park has been working to understand the underlying mechanisms of the targeted chemotherapy venetoclax. Their findings, to be presented during a talk today at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California, provide strong preclinical evidence that adding venetoclax to standard treatment may improve outcomes in patients with treatment-resistant B-cell lymphomas.
Could US-style summer holiday programs boost Aussie kids’ health?
As the school year winds up, thousands of Aussie kids are looking forward to the summer holidays. But hand-in hand with this freedom comes an abundance of screentime, unhealthy snacks, and a lack of routine, and it has the potential to affect children’s physical and mental health.
New Members Named to CSUF Philanthropic Foundation Board of Governors
Community leaders and entrepreneurs are among the newest members of Cal State Fullerton’s Philanthropic Foundation Board of Governors, the nonprofit auxiliary organization established to build and strengthen CSUF’s relations with the community and encourage advocacy, investment in and support of the university.
Toxoplasma gondii parasite uses unconventional method to make proteins for evasion of drug treatment
A study sheds new light on how Toxoplasma gondii parasites make the proteins they need to enter a dormant stage that allows them to escape drug treatment.
Four Argonne researchers recognized on the American Nuclear Society’s “40 Under 40” list
Dave Grabaskas, Paul Romano, Ben Lindley and April Novak are recognized by American Nuclear Society on Nuclear News’ highly selective list of rising stars in nuclear research
ASH: Monoclonal antibody therapy improves survival in cancer-associated hyper-inflammatory disorder
Adult patients with newly diagnosed malignancy-associated hemophagocytic lymphohistiocytosis (mHLH) – a rare, aggressive hyperinflammatory condition – who were treated with the first-in-class monoclonal antibody, ELA026, experienced a 100% response rate and an improved survival rate at two months, according to researchers from The University of Texas MD Anderson Cancer Center.
Lighting Campus for Hope: A Winter Wonderland of Resilience and Community
More than just a holiday gathering, this free, family-friendly event marked the culmination of a year-long appeal that raised $255,000 to provide 1,350 life-saving cancer screenings in our Borderplex community. Every dollar from event sponsorships will directly support cancer screenings and diagnostics, emphasizing the transformative impact of early detection and care.
Considering social and genetic factors in addition to clinical factors improves prediction of heart disease risk
A cohort study evaluated how polygenic risk scores (PRS) and polysocial scores (PSS), which include social determinants of health (SDOH) and lifestyle-psychological factors, correlate to risk of coronary heart disease (CHD) by developing a CHD prediction model incorporating these elements.
Experts debate management of patient with gastroesophageal reflux symptoms
In a new Annals “Beyond the Guidelines” feature, two physicians, a primary care practitioner and a gastroenterologist, discuss the management of a patient with gastroesophageal reflux disease (GERD) symptoms. GERD is a common medical condition presenting with heartburn, regurgitation, cough, hoarseness and/or wheezing.
The VR Technologist Will See You Now
If your heart rate increases each time you hear the word “injection,” you’re not alone. Every 1 in 4 adults has a fear of needles—a fear that most attribute to an experience they had when they were children.For kids who visit the hospital frequently, anxiety around even routine procedures might interfere with each visit and even lead to long-term trauma.
Why the FDA Should Move Fast to Regulate Nicotine Pouches
In a commentary published in JAMA, experts at the Rutgers Institute for Nicotine & Tobacco Studies have issued a call to action to head off the proliferation of nicotine pouches based on lessons learned from electronic-cigarette regulation
Loneliness and isolation: Back to pre-pandemic levels, but still high, for older adults
Loneliness and isolation among older Americans have mostly returned to pre-pandemic rates, but that still means more than one third of people age 50 to 80 feel lonely, and nearly as many feel isolated, a new national study shows.
RATE-XR Guideline Sets New Standard for XR Clinical Research
A landmark guideline in extended reality clinical research sets a new standard in reporting, ensuring transparency, safety, and quality.
Machine Learning for Predicting Corporate Violations: How Do CEO Characteristics Matter?
Abstract Based on upper echelon theory, we employ machine learning to explore how CEO characteristics influence corporate violations using a large-scale dataset of listed firms in China for the period 2010–2020. Comparing ten machine learning methods, we find that eXtreme…
STUDENTS ARE LESS LIKELY TO FEEL SAFE AT THEIR SCHOOLS, COMPARED TO STAFF AND PARENTS
Researchers at the University of Southern California (USC) conducted a nationwide study of K-12 parents, K-12 teachers, and recently graduated high school students to test their responses to three hypothetical “threat scenarios.” The goal was to measure their perception of school safety as well as their likelihood to report a threat at school.
Fusion with a Twist: Improving Stellarators
Plasma many times hotter than the surface of the sun swirls inside of a large device. From the outside, the device looks like a metal ring surrounded by scaffolding and walkways. But inside, the device is creating the conditions needed to achieve fusion – the process that powers our sun and every star.
Did Facebook Cheat?: A Test Case of Antitrust Ethics
Abstract Citing corporate concentration and lax enforcement since the Reagan era, the Biden administration has declared a new era of aggressive antitrust prosecution, bringing antimonopoly actions against tech giants such as Meta, Google, and Amazon. But what’s so bad about…
Learning from Failures of Co-owned Firms: Common Ownership and Information Disclosure Fraud
Abstract This study focuses on learning effects between firms connected by common ownership. We explore the learning effects in a certain setting that how decision-makers in focal firms learn from punishments for fraudulent disclosure in their co-owned firms. Baseline results…
Woods Hole Oceanographic Institution and partners discover new ocean predator in the Atacama Trench
This crustacean is the first large, active predatory amphipod from these extreme depths.
Chula Pioneers Responsible Use of Generative AI for Higher Education in Thailand with the Inauguration of ‘ChulaGENIE,’ in Collaboration with Google Cloud
Chulalongkorn University (Chula), Thailand’s pre-eminent higher education institution, and Google Cloud today announced the inauguration of ChulaGENIE, a continuous application delivery project that makes the world’s most advanced generative AI (gen AI) capabilities safely, securely, and freely available to Chula’s entire community. ChulaGENIE will be initially available to Chula staff and faculty members in January 2025, with all students receiving access in March 2025. ChulaGENIE stands for ‘Chula’s Generative AI Environment for Nurturing Intelligence and Education.’
Precision diabetes management: glucose-triggered insulin delivery membrane
Scientists have developed an innovative glucose-responsive membrane capable of self-regulating insulin release, offering a potential revolution in diabetes management. This cutting-edge material responds to glucose levels by contracting, functioning as an automatic chemical valve that controls insulin delivery.
Top Managers’ Rice Culture and Corporate Social Responsibility Performance
Abstract Ecological psychology regards culture as a response to the demands of the environment. As rice farming in history has significantly influenced the formation of human cultural consciousness, we investigate how the rice culture of a chairperson’s birthplace affects a…
Giving a gift? Better late than never, study finds
If you feel terrible about giving a late gift to a friend for Christmas or their birthday, a new study has good news for you. Researchers found that recipients aren’t nearly as upset about getting a late gift as givers assume they will be.
Vincent Aurentz Joins Forward Therapeutics’ Board of Directors
Forward Therapeutics, Inc., a pioneering biopharmaceutical company committed to transforming the treatment of chronic inflammatory disorders, today announced the appointment of Vincent Aurentz to its board of directors.
Inspiring Minds: Nobel Laureates Illuminate CityUHK
City University of Hong Kong (CityUHK) recently hosted two inspiring events featuring Nobel Laureates, offering students and faculty members a rare opportunity to engage with world-renowned scientists.
New Study Reveals Key Insights on Sarcoma Rates in Military vs. Civilian Men
Researchers at the Uniformed Services University of the Health Sciences (USU) have uncovered compelling insights into the incidence of soft tissue sarcomas among U.S. active-duty servicemen, revealing significant age-related differences compared to the general male population. The findings shed light on the interplay between occupational exposures, healthcare access, and cancer risk, paving the way for targeted prevention strategies and future research.
Children’s Hospital of Philadelphia Researchers Find Rotavirus Vaccine is Safe for Use in NICU Babies
Researchers found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks. The findings could serve as the basis for a change in clinical practice.
Developing wastewater treatment units that treat right where it’s generated
Dr. Sang Hoon Kim, Extreme Materials Research Center, Dr. Jong Min Kim, Materials Architecturing Research Center, and Dr. Sang Soo Han, Computation Science Research Center, all from the Korea Institute of Science and Technology (KIST), have developed an electrochemical device that can treat sewage and wastewater from pollution sites to the level of discharge. In particular, it can rapidly and completely decompose recalcitrant materials into inorganic substances and discharge them on its own.
Resistance Training Can Reduce Fatigue, Pain in Multiple Myeloma Patients, Roswell Park Team Shows
Researchers from Roswell Park Comprehensive Cancer Center will present compelling findings showcasing significant benefits of resistance training for patients with multiple myeloma, in a talk at the 66th American Society of Hematology (ASH) Annual Meeting. The study, led by Jens Hillengass, MD, PhD, and Janine Joseph, MS, MBA, presents new evidence documenting that targeted exercise regimens can alleviate fatigue, improve sleep and reduce pain, offering new hope for enhancing quality of life in cancer care.
Roswell Park Experts Report Insights on CAR T for Follicular Lymphoma, KEYNOTE-667 Combo in Hodgkin Lymphoma
The results of two important lymphoma studies led by experts at Roswell Park Comprehensive Cancer Center will be presented during oral abstract sessions this morning at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California. Lymphoma is a type of blood cancer that causes white blood cells called lymphocytes to grow out of control and behave abnormally.
ASH 2024: Antibody Shows Encouraging Results for Treating High-risk Follicular Lymphoma and Marginal Zone Lymphoma
ASH 2024 Presentations: Two clinical trials testing the antibody loncastuximab tesirine (Zynlonta) showed encouraging results in patients with high-risk forms of two blood cancers – follicular lymphoma and marginal zone lymphoma.
Multi-center study shows education level, income impact access to stem cell transplantation for acute myeloid leukemia patients
Patients with acute myeloid leukemia who have lower education levels and lower income are less likely to receive a allogeneic hematopoietic stem cell transplant for acute myeloid, however, if they can access the treatment, are equally likely to benefit from transplant as patients with more education and higher income, according to a new study from Fred Hutch Cancer Center presented at the annual meeting of the American Society of Hematology.
Preclinical Study Shows Targeted Drug Strengthens the Power of CAR T-Cell Therapy in Two Pediatric Leukemias
A preclinical study led by a faculty member at Roswell Park Comprehensive Cancer Center shows that gilteritinib (brand name Xospata), a targeted cancer treatment, can strengthen chimeric antigen receptor (CAR) T-cell immunotherapy in two high-risk pediatric leukemias that have poor survival rates — FLT3-mutated acute myeloid leukemia (AML) and KMT2A-rearranged acute lymphoblastic leukemia (ALL). Lisa Niswander, MD, PhD, Assistant Professor of Oncology in the Department of Pediatric Oncology, will deliver the results this afternoon in an oral abstract session at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California.
Roswell Park Study Reveals How Venetoclax Boosts Immune Response to CAR T for Chronic Lymphocytic Leukemia
Research out of Roswell Park Comprehensive Cancer Center has shed light on how the drug venetoclax (brand name Venclexta) works synergistically with CAR T-cell immunotherapy to combat chronic lymphocytic leukemia (CLL), the most common type of leukemia in the U.S. Matthew Cortese, MD, MPH, Assistant Professor of Oncology in Roswell Park’s departments of Medicine and Cancer Genetics & Genomics, is first author of the study, which he will present during an oral abstract session today at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California.
Keto diet metabolite may power up CAR T cells to kill cancer
A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center, presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition (Abstract 4).
New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented during the plenary session at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego on December 8.
Cedars-Sinai Pharmacists Attending Midyear Clinical Meeting 2024
Cedars-Sinai experts in pharmacy services attending the Dec. 8-12 American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting 2024 in New Orleans are available for interviews about the latest developments in patient safety and pharmacy practice.
Thawing Permafrost Reveals Complex Microbiome–Metabolite Interplay
Research led by a multi-institutional study found that microbes interact with sulfur- and nitrogen-rich compounds, possibly from mosses in bogs. This interaction appears to contribute to greenhouse gas production.
CSUF Among Top 5 National Institutions for Bachelor’s Degrees to Latinx Students
Cal State Fullerton ranked No. 4 in the nation among four-year schools for the total number of bachelor’s degrees awarded to Latinx students in both Hispanic Outlook in Higher Education’s 2024 “Top 100 Colleges and Universities for Hispanics” and Diverse: Issues In Higher Education’s 2024 “Top 100 Degree Producers” rankings.
Illinois research illuminates signal transduction mechanisms in Cys-loop receptors
University of Illinois researchers discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the field of ion-channel physiology and contributing to rational drug design.
How Caregivers of People With Dementia Can Navigate the Holidays
Although the holiday season brings joy to many, it may mean added stress for those supporting a family member with memory loss. Mary-Catherine Lundquist, the program director of Care2Caregivers, a peer counseling helpline (800-424-2494) for caregivers of individuals with Alzheimer’s disease and related memory disorders operated by Rutgers Behavioral Health Care, discusses how families can make the most of the season.
Navigating the holiday season: MSU experts can comment
It’s the most wonderful time of the year, right? Not necessarily. We all know that the holidays can cause stress and angst as we cook, shop, entertain and spend time with family and friends we may not see often. Michigan State University experts offer suggestions on navigating the holiday — from the economy and food prices to religion and spirituality to health and relationships.
Sacrificing Sleep During the Holiday Season
A new survey from the American Academy of Sleep Medicine reveals that more than half of Americans (55%) say they are extremely or somewhat tired during the holiday season.
Expert Available to Talk about South Korea’s Martial Law Updates
George A. Lopez is the Rev. Theodore M. Hesburgh, C.S.C., Professor Emeritus of Peace Studies at the Kroc Institute for International Peace Studies in the Keough School of Global Affairs at the University of Notre Dame, and a former member of the UN Panel of Experts…
Researchers are Going to Map Cells Crucial to Child Respiratory Health and Disease
A research project co-led by researchers at the UNC School of Medicine and colleagues, will create an atlas of the cells in the nasal and oral cavities, throat, and lower airways of pediatric populations in unprecedented detail.
VUMC to study the effect of breathing tube size on breathing, speaking, swallowing
Vanderbilt University Medical Center has been approved for $7 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) to study the effect of breathing tube size on breathing, speaking and swallowing after critical illness.
Calculation Sharpens Imaging of Protons’ Insides
Nuclear scientists used a new theoretical approach to calculate a value essential for unraveling the three-dimensional motion of quarks within a proton. The researchers obtained a significantly more accurate picture of these internal building blocks’ transverse motion. The work will aid in calculations of 3D motion of quarks and gluons in future collider experiments.
Dark Energy Camera Spies the Outskirts of the Swirling Southern Pinwheel Galaxy
Twelve million light-years away lies the galactic masterpiece Messier 83, also known as the Southern Pinwheel Galaxy. Its swirling spiral arms display a high rate of star formation and have been host to six observed supernovae. This image was captured with the Department of Energy-fabricated Dark Energy Camera, mounted on the U.S. National Science Foundation Víctor M. Blanco 4-meter Telescope at Cerro Tololo Inter-American Observatory in Chile, a Program of NSF NOIRLab.