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UrduResearchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD).
Tag: Ion Channel
Surprising discovery by UCI-led team links Piezo1 and cholesterol during brain development
A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.
Sonothermogenetic pulse controls mouse behavior
Bioengineers are using focused ultrasound to modulate motor activity in the brain without surgical device implantation, a first step toward non-invasive brain stimulation therapies.
Depth of perception
Minuscule tunnels through the cell membrane help cells to perceive and respond to mechanical forces, such as pressure or touch. Using tip-growing cells in moss and pollen tubes of flowering plants, a new study is among the first to directly investigate what one type of these mechanosensitive ion channels — PIEZO channels — is doing in plant cells, and how.
Researchers Identify Brain Ion Channel as New Approach to Treating Depression
Researchers from the Icahn School of Medicine at Mount Sinai have identified a drug that works against depression by a completely different mechanism than existing treatments.
Researchers Discover a Novel Potassium Channel Activator Which Acts as a Potential Anticonvulsant
Corresponding Authors: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience, Director, Center for Neurotechnology & Behavior, Icahn School of Medicine at Mount Sinai, New York (lead) Avner Schlessinger, PhD, Associate Professor, Department of Pharmacological Sciences, Associate…
Chemotherapy and Cancer Gang up to Cause a Neurological Side Effect, Study Says
Chemotherapy has been the lone suspect in a neurological ailment, but cancer may be also to blame. The havoc they wreak is much more than additive.