Study of AI-enabled EKGs finds that a difference between numerical age and biological age significantly affects health, longevity

You might be older ― or younger ― than you think. A new study found that differences between a person’s age in years and his or her biological age, as predicted by an artificial intelligence (AI)-enabled EKG, can provide measurable insights into health and longevity.

Accounting for finance is key for climate mitigation pathways

A new study highlights the opportunity to complement climate mitigation scenarios with scenarios that capture the interdependence among investors’ perception of future climate risk, the credibility of climate policies, and the allocation of investments across low- and high-carbon assets in the economy.

Why are some Covid-19 vaccines working better for men than women?

If there’s one take-home message for the general public about the coronavirus vaccines approved in the U.S., it’s that they are remarkably effective. But Michigan State University’s Morteza Mahmoudi is raising awareness about an important subtlety: The vaccines developed by Moderna and Pfizer-BioNTech appear to work slightly better for men than for women.

SPECIAL ISSUE ON THE COVID-19 PANDEMIC

The international journal Risk Analysis has published a timely special issue for May 2021, “Global Systemic Risk and Resilience for Novel Coronavirus and COVID-19.” Featuring 11 papers written for this issue over the past year, the collection represents a sampling of insights and viewpoints from scholars across risk sciences and resilience analytics to guide decision-making and operations related to the COVID-19 pandemic.

Older Adults with Functional Impairments Linked to Prescription Drug Use/Misuse

Researchers at University of California San Diego School of Medicine found that functional impairments among adults aged 50 and older are associated with a higher risk of medical cannabis use; and prescription opioid and tranquilizer/sedative use and misuse.

Nearly 3% of Americans take immune-weakening drugs that may limit COVID vaccine response

A study of more than 3 million insured U.S. adult patients under 65 found that nearly 3% take immunosuppressive drugs that may elevate risk for severe COVID-19 symptoms and hospitalization if they became infected. There is growing evidence that immunosuppressive drugs may also reduce the COVID vaccine’s efficacy.

New AI-based tool can find rare cell populations in large single-cell datasets

MD Anderson researchers have developed a first-of-its-kind AI tool to identify rare groups of biologically important cells from the noise of large, complex single-cell datasets. The new tool, called SCMER, can help reserachers gain new insights across many applications.

Weight cycling linked to increased sleep problems in women

Women with a history of weight cycling – losing and regaining 10 pounds or more, even once – have increased rates of insomnia and other sleep problems, reports a study in The Journal of Cardiovascular Nursing, official journal of the Preventive Cardiovascular Nurses Association. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Deep Learning Enables Dual Screening for Cancer and Cardiovascular Disease

In research published today in Nature Communications, a team of engineers from Rensselaer Polytechnic Institute and clinicians from Massachusetts General Hospital developed a deep learning algorithm that can help assess a patient’s risk of cardiovascular disease with the same low-dose computerized tomography (CT) scan used to screen for lung cancer. This approach paves the way for more efficient, more cost-effective, and lower radiation diagnoses, without requiring patients to undergo a second CT scan.

Experimental Drug Makes Radiation Therapy More Effective, Less Damaging

DALLAS – May 20, 2021 – An experimental drug that has shown promise in protecting healthy tissue from collateral damage caused by radiation therapy for cancer also appears to enhance radiation’s capacity to kill tumors, a new study led by UT Southwestern scientists shows. The findings, published online in Science Translational Medicine, could provide a much-needed boost to the radiation treatments used against a variety of tumor types.

Multi-story buildings made of wood sell for 9% more than other construction in Helsinki

Building more homes and buildings with wood has been on the radar for years as a way to offset carbon emissions, though construction companies have been hesitant to take the material in broader use. A study at Aalto University in Finland is now the first to show that building with wood can be a sound investment.

New NUS technology completes vital class of industrial reactions five times faster

Researchers from NUS Engineering have developed a new method to increase the rate of an important chemical reaction known as hydrogenation by more than 5 times. Hydrogenation is used in the production of everyday items like plastics, fertilisers, and pharmaceuticals. The NUS team’s novel approach is a more direct and effective method that can lead to higher yields for industries and lower environmental impacts.

Children’s sleep and adenotonsillectomy

While a pint-sized snorer may seem adorable, studies shows that children with sleep disordered breathing are likely to show aggressive and hyperactive behaviours during the day. The recommended treatment is an adenotonsillectomy – not only to fix the snore, but also the behaviour. Now, new research from the University of South Australia, shows that while surgery can cure a child’s snoring it doesn’t change their behaviour, despite common misconceptions by parents and doctors alike.

Researchers find that blocking a protein in liver cells protects against insulin resistance and fatty liver disease

A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice. ABCB10 activity also prompted insulin resistance in human liver cells.

Final results of SPRINT study confirm controlling blood pressure critically important in preventing heart disease and stroke

News release about the follow-up data from the landmark SPRINT study of the effect of high blood pressure on cardiovascular disease have confirmed that aggressive blood pressure management — lowering systolic blood pressure to less than 120 mm Hg — dramatically reduces the risk of heart disease, stroke, and death from these diseases, as well as death from all causes, compared to lowering systolic blood pressure to less than 140 mm Hg.

Experts Available and Research to Be Presented in Bladder Cancer, Disparities in Cancer and Other Areas at the 2021 ASCO Annual Meeting

The virtual Annual Meeting of the American Society of Clinical Oncology (ASCO), the largest medical meeting on the latest cancer research findings, will include several presentations by investigators from The Tisch Cancer Institute at Mount Sinai. Mount Sinai physician scientists will present leading research studies, including oral presentations on bladder cancer and disparities in cancer.

Combination therapy achieves high rates of response for patients with acute lymphoblastic leukemia

A combination of ponatinib and blinatumomab was found to be safe and highly effective in patients with newly diagnosed or relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL), according to researchers at The University of Texas MD Anderson Cancer Center. The study may support a regimen to produce complete remission with front-line therapy, without the increased risks associated with systemic chemotherapy or a stem cell transplant.

Dana-Farber researchers present key studies at ASCO annual meeting

Dana-Farber Cancer Institute researchers are presenting dozens of research studies at the 2021 Annual Meeting of the American Society of Clinical Oncology (ASCO). The studies will be presented during the virtual program on June 4-8, 2021. ASCO is the world’s largest clinical cancer research meeting, attracting more than 30,000 oncology professionals from around the world.

Physicists Crack the Code to Signature Superconductor Kink Using Supercomputing

A team performed simulations on the Summit supercomputer and found that electrons in cuprates interact with phonons much more strongly than was previously thought, leading to experimentally observed “kinks” in the relationship between an electron’s energy and the momentum it carries.

More affirmation, less punishment may reduce harm to Black girls in schools, researchers assert

To improve the experiences of Black children in schools, particularly Black girls, a pair of researchers have conceptualized a new framework to help school leaders rethink anti-Black policies and practices, and help Black children recognize and celebrate their cultural identity.