news, journals and articles from all over the world.
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk — in opposite directions — for developing colon cancer.
A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease. In 14 countries, including the United States, rates are increasing in young adults while stabilizing in those 50 years and older. The research is published today in the journal The Lancet Oncology.
BACKGROUNDRecent advancements in nanomedicine have highlighted the potential of exosome (Ex)-based therapies, utilizing naturally derived nanoparticles, as a novel approach to targeted cancer treatment. AIMTo explore the targetability and
Think you’re too young for colon cancer? Think again! He was a teenage heart throb and pop icon as a young star on “Dawson’s Creek.” Now James Van Der Beek is once again an icon for people his age. The…
Younger adults with colon cancer tend to be diagnosed at a later stage and have more aggressive types of tumors. Additionally, young patients living with colorectal cancer have long-term, adverse consequences on their lives, which are different from the impact the disease* has on older adults, according to two studies being presented at the American College of Surgeons (ACS) Clinical Congress 2024 in San Francisco, California.
National Cleveland Clinic Survey Examines Generational Divide in Men’s Health
A mouthwash-like rinse to predict head and neck cancer recurrence, new research identifies biomarkers to predict which colon cancer patients benefit from adjuvant chemotherapy, the Dolphins Cancer Challenge and more are included in this month’s tip sheet.
Harrisburg, PA – Welcome to your July 2024 Harrisburg University of Science and Technology (HU) Research Roundup! Our talented students and faculty members are busy presenting at conferences, publishing boundary-pushing research, and building fruitful partnerships with schools, agencies, and organizations.…
An analysis of data from a randomized clinical trial for patients with stage 3 colon cancer found that those with PIK3CA mutations who took celecoxib, an anti-inflammatory drug, after surgery lived significantly longer and had longer disease-free survival compared to those without the mutation.
In a trial analyzing how messages were framed in an underserved population, offering colorectal cancer screening options resulted in the highest screening rate
An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego.
Researchers at Case Western Reserve University’s School of Medicine believe they have found information that could lead to developing new treatment options for people with metastatic colorectal cancer.
Two researchers from The University of Texas MD Anderson Cancer Center will be honored with Scientific Achievement Awards at the American Association for Cancer Research (AACR) Annual Meeting 2024 for accomplishments in clinical and translational research as well as outstanding leadership in oncology.
SEATTLE — April 3, 2024 — Below are summaries of recent Fred Hutchinson Cancer Center research findings, patient stories and other news. If you’re covering the American Association for Cancer Research (AACR) Annual Meeting, please see our list of and contact to set up interviews.
The American College of Gastroenterology Free Virtual Event on March 28, 2024, at 8:00 pm ET, “Tune It Up: A Concert To Raise Colorectal Cancer Awareness”
David Winter, MD, at Baylor Scott & White Health, discusses why cancer is impacting more young people. What You Need to Know: People aged 50 and older are living longer because of better cancer detection and treatments. Cancer diagnosis in…
The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers. New research in mice from investigators at the Johns Hopkins Kimmel Cancer Center demonstrates that these regions also have distinct transcriptional programs, or cellular processes, that regulate the development of normal and cancerous cells.
New research from the University of Ottawa proposes using vanoxerine as a safe method for potentially eliminating cancer stem cells in colorectal tumors.
In new findings led by researchers at the American Cancer Society, Martin-Luther University in Germany, and many other institutes worldwide, fewer than one in 20 patients diagnosed with potentially curable colorectal cancer received standard of care in Sub-Saharan Africa.
Mayo Clinic Comprehensive Cancer Center researchers have identified key findings that can assist clinicians in predicting whether a patient with advanced colorectal cancer will benefit from immunotherapy.
Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster.
More than 4 out of 5 older women survivors of colorectal cancer may be experiencing a range of gastrointestinal symptoms many years after being diagnosed and treated, a new study suggests.
Baylor Scott & White Health once again leads the state of Texas in the number of accolades earned in U.S. News & World Report’s 2023-24 Best Hospitals, released today. A total of 26 Baylor Scott & White hospitals were recognized, including four facilities with a nationally ranked specialty – more than any other health system in Texas.
Baylor Scott & White Health once again leads the state of Texas in the number of accolades earned in U.S. News & World Report’s 2023-24 Best Hospitals, released today. A total of 26 Baylor Scott & White hospitals were recognized, including four facilities with a nationally ranked specialty – more than any other health system in Texas.
New AI tool accurately predicts both overall survival and disease-free survival after colorectal cancer diagnosis.
The model uses visual markers on pathology images to glean insights into a tumor’s genomic profile and predicts tumor behavior, disease progression, treatment response.
The new model could help augment clinical decision-making.
Because the AI tool relies on images alone, it could be particularly valuable for hospitals lacking the technology or expertise to perform sophisticated genomic profiling of tumor tissues.
A new editorial paper was published in Oncoscience (Volume 10) on March 23, 2023, entitled, “New method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing.”
Article title: Genomic and epigenomic responses to aspirin in human colonic organoids Authors: David Witonsky, Margaret C. Bielski, Jinchao Li, Kristi M. Lawrence, Ishmael N. Mendoza, Hina Usman, Sonia S. Kupfer From the authors: “This is the first study to…
Studies show that certain bacteria may contribute to the development of colorectal cancer by producing toxins that may damage colon cells or cause an accumulation of DNA mutations and/or intestinal inflammation. Now, researchers are looking at the possibility that certain…
Researchers studied human colon cancer tissue samples and animal models and found that exposure to salmonella was linked with colon cancers that developed earlier and grew larger.
New research in JNCCN finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).
Researchers have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells.
Nikolaos T. Pyrsopoulos, chief of the division of gastroenterology and hepatology at Rutgers New Jersey Medical School, is available to discuss the NEJM study on the efficacy of colonoscopy in detecting colon cancers and extending life. If you do not…
A research team from the lab of Quing Zhu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering at the McKelvey School of Engineering at Washington University in St. Louis, has combined optical coherence tomography (OCT) and machine learning to develop a colorectal cancer imaging tool that may one day improve the traditional endoscopy currently used by doctors.
Younger adults living in the U.S. are less likely to be screened for colorectal cancer than older U.S. adults, despite now being eligible under new screening guidelines, and face greater disparities than older U.S. adults who are eligible for screening, according to research from UTHealth Houston.
A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system’s “natural killer” cells, shows a study by researchers at the University of California San Diego. In mouse models of colon cancer, the combination therapy eliminated all tumors and prevented their recurrence, which in turn resulted in 100% survival. The therapy also increased survival in mouse models of melanoma.
Researchers from Wake Forest University School of Medicine have discovered a possible new approach in treating solid tumors through the creation of a novel nanoparticle.
A multi-institutional, international study, led by researchers at the Johns Hopkins Kimmel Cancer Center and WEHI in Melbourne, Australia, found that testing for ctDNA after surgery and directing chemotherapy to ctDNA-positive patients reduced the use of chemotherapy overall without compromising recurrence-free survival.
Zulu Social Aid and Pleasure Club Presents Men’s Health Fair, Sponsored by Ochsner Xavier Institute of Health Equity and Research.
Chula Engineering and Chula Medicine co-invent an innovative device for a rapid gastrointestinal cancer detection that yields accurate results hoping to foster preventive medicine in gastrointestinal malignancy and reduce the number of cancer patients.
Colonoscopies performed with artificial intelligence saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, according to new data presented at the 2022 Digestive Disease Week Annual Meeting.
Investigators from Rutgers Cancer Institute of New Jersey, New Jersey’s only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.
A safe, localized treatment for chronic inflammation in the intestinal tract will move one step closer to helping patients reduce their risk of developing colon cancer.
Fight Colorectal Cancer Hosts Gut-Friendly Cooking Event Alongside Best-Selling Cookbook Author and Former Food Director at Real Simple.
Two research teams have developed new noninvasive tests that use either blood or saliva samples to diagnose cases of colorectal cancer or prostate cancer, respectively. Presented today at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo, these tests could facilitate screening efforts for colorectal cancer and allow clinicians to better distinguish early-stage prostate cancer from more benign prostate conditions.
Researchers are finding a link between the increased presence of certain bacteria in a gut biome and colon cancer.
Infants whose mothers were obese during pregnancy may have a heightened risk of developing colorectal cancer later in life, according to new research led by public health experts at The University of Texas Health Science Center at Houston (UTHealth).
Selected Recipients of the New “Back to Screening Award for Research Advocacy Excellence” will be Honored at Fight Colorectal Cancer’s “Path to a Cure” Event in December 2021.
New and updated patient and caregiver resources from National Comprehensive Cancer Network (NCCN) offer jargon-free, state-of-the-art information on diagnosis, treatment, and surveillance for anal, colon, and rectal cancers.
In many countries around the world, patients under age 50 are fighting, some dying, of colon and rectal cancers. Early-Age Onset Colorectal Cancer is an urgent issue in cancer research and patient care around the globe. We all want to know why this is happening, fully aware that for some, time is running out.
Dr. Rachel Issaka, a gastroenterologist and assistant professor with UW Medicine, talks about the significance of the new recommendation and what it may mean for the Black community.
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