Researchers identify proteins that prevent COVID-19 transmission through the placenta

Researchers from Boston Medical Center’s Maxwell Finland Laboratory for Infectious Diseases have identified properties in placenta tissue that may play an important role in preventing the transmission of COVID-19 from a mother with the virus to her fetus.

An Unprecedented Discovery of Cell Fusion

Understanding how bacteria interact is critical to solving growing problems such as antibiotic resistance, in which infectious bacteria form defenses to thwart the medicines used to fight them. Researchers at the University of Delaware have discovered that bacterial cells from different species can combine into unique hybrid cells by fusing their cell walls and membranes and sharing cellular contents, including proteins and ribonucleic acid (RNA), the molecules which regulate gene expression and control cell metabolism.

After Medicaid Expansion, ‘Unmet Need’ for Joint Replacement Surgery

States that have expanded Medicaid eligibility under the Affordable Care Act have seen an “early surge in demand” for hip and knee replacement surgery, reports a study in the September 2, 2020 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

New study on migration success reinforces need for monarch butterfly milkweed habitat

A recently published study presents evidence that the migration success of monarchs hasn’t declined in recent years and thus cannot explain the steep decline in the monarch population over the last few decades. The study drew on data collected on 1.4 million monarch butterflies that were tagged in the United States Midwest from 1998 to 2015 and emphasizes the need for new monarch habitat.

Study Details How General Anesthetics And ‘Benzos’ Act on Receptors in The Brain

As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor. Now UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines – which also bind to the GABAA receptor. The findings were published online today in the journal Nature.

Paper ballots, risk-limiting audits can help defend elections and democracy, IU study finds

With just over two months before the 2020 election, three professors at the Indiana University Kelley School of Business offer a comprehensive review of how other nations are seeking to protect their democratic institutions and presents how a multifaceted, targeted approach is needed to achieve that goal in the U.S., where intelligence officials have warned that Russia and other rivals are again attempting to undermine our democracy.

Adjusting Jailed Women’s Beliefs about Their Friends’ Substance Use May Help Reduce Their Drinking and Risk of Reoffending

Brief interventions can potentially reduce incarcerated women’s alcohol use when they leave jail, according to a new study. Researchers explored jailed women’s impressions of how their friends and acquaintances drank and used drugs (“social norms”). Research shows that people who perceive their friends drinking heavily are more likely to drink heavily themselves, while individuals who realize that their friends in fact drink moderately tend to reduce their own alcohol use. Often, perceptions of substance use in a social network are skewed. Past research on this phenomenon has focused on college students, with slight attention to people involved in the criminal justice system. Two in three incarcerated adults have a substance use disorder — compared to one in ten of the general population — and consequently may regard their own alcohol and drug use as typical. Substance use is strongly implicated in criminal justice involvement and reoffending, especially for women. This study in Alcoho

Guilt by Dissociation: Study Sheds Light on Serotonin in Autism

A study on serotonin, a mood-regulating molecule in the brain that regulates many brain synapses, is helping to unravel the puzzle surrounding its role in autism. The activity and regulation of the serotonin transporter (SERT), protein is critically dependent on a number of other proteins that tell the protein where to locate on nerve cells and how to act. Shifts in the transporter’s activity can significantly impact the ability of serotonin to act in the brain.

Anxiety and loneliness decline since the COVID-19 pandemic began, but more than one-third of Americans report increased depression, study by the USC Center for the Digital Future finds

Increased levels of loneliness and anxiety reported early in the COVID-19 pandemic have declined in recent months, but about one-third of Americans say they are more depressed since the pandemic began, according to a study by the USC Center for the Digital Future.

HSS Doctors Offer Practical Advice on Reaching Peak Performance During Surgical Training in AAOS Journal

Studies show that athletes and musicians achieve peak performance by constant practice, by setting specific goals, having strong mentors and cultivating perseverance, stoicism and grit. Could incorporating these principles into the training of surgeons improve their residency experience?

Effective Cancer Immunotherapy Further Linked To Regulating A Cell ‘Suicide’ Gene

Johns Hopkins Medicine researchers have added to evidence that a gene responsible for turning off a cell’s natural “suicide” signals may also be the culprit in making breast cancer and melanoma cells resistant to therapies that use the immune system to fight cancer. A summary of the research, conducted with mice and human cells, appeared Aug. 25 in Cell Reports.

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Food insecurity and schools during the pandemic

The coronavirus pandemic has brought a number of challenges to schools, which were forced to close in the spring to help slow the spread of infection. One major challenge for schools was ensuring that students’ nutritional supplementation needs were met when they were not attending school in person.As schools across the country begin to welcome students back in person or for virtual learning, equity must be at the forefront of decisions pertaining to school emergency food services, finds a new study from the Brown School at Washington University in St. Louis.

Face Shield or Face Mask to Stop the Spread of COVID-19?

If CDC guidelines aren’t enough to convince you that face shields alone shouldn’t be used to stop the spread of COVID-19, then maybe a new visualization study will. Researchers simulated coughing and sneezing from a mannequin’s mouth using a laser light to visualize droplets expelled. They tested a plastic face shield and found that they block the initial forward motion of the exhaled jet, however, aerosolized droplets are able to move around the visor with relative ease.

Decorating Windows for Optimal Sound Transmission

Glass windows typically offer some amount of sound proofing, sometimes unintentionally. In general, ventilation is required to achieve large sound transmission. But some applications — like gas explosion studies — require a transparent partition that allows for acoustic propagation without the presence of airflow. In those cases, ventilation is not allowed. In Applied Physics Letters, researchers discuss a layered glass material they developed that allows for efficient sound transmission with no air ventilation.

Detecting Small Amounts of Virus in Early Infections

Diagnostic devices that are used at home or in doctors’ offices are often not sensitive enough to detect small amounts of a virus that might be present in samples from asymptomatic patients, which can occur in early stage COVID-19. In Biomicrofluidics, scientists report a membrane-based invention that can concentrate the virus content of a sample of urine or saliva, allowing it to be detected.