Stem cell treatment for dementia clears major hurdle

UCLA researchers have successfully grown restorative brain cells in large batches suitable for transplantation in patients. The therapy is designed to repair damage to the brain from white matter stroke, a “silent stroke” that can kick off years of cognitive deterioration and can accelerate Alzheimer’s disease. A new paper is published in the journal Stem Cell Research.

Stem cell treatment for dementia clears major hurdle

UCLA researchers have successfully grown restorative brain cells in large batches suitable for transplantation in patients. The therapy is designed to repair damage to the brain from white matter stroke, a “silent stroke” that can kick off years of cognitive deterioration and can accelerate Alzheimer’s disease. A new paper is published in the journal Stem Cell Research.

Study finds recent change in EMS transport policy could improve stroke outcomes

A new EMS transport policy implemented in Chicago showed that sending patients suspected of experiencing large vessel occlusion directly to comprehensive stroke centers led to an increase in the use of endovascular therapy, an important treatment for acute ischemic stroke.

Understanding Alzheimer’s Progression with Improvements to Imaging, Image Processing, Machine Learning

Because there is no ethical way to extract brain tissue from patients to look for clues about how amyloid plaques and protein aggregates proliferate, supplementary techniques are needed to better understand the progression of Alzheimer’s disease. During ACA’s 71st annual meeting, Abdullah Al Bashit, from Northeastern University, will discuss using computational techniques to help address these challenges. His work demonstrates how using small and wide-angle scattering along with state-of-the-art detection techniques will help probe the molecular structure and proliferation.

Metabolic Syndrome Linked to Increased Risk of Second Stroke, Death

People with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at higher risk for having a second stroke and even dying than people who do not have metabolic syndrome, according to a meta-analysis published in the July 28, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Study: Adding Color to Your Plate May Lower Risk of Cognitive Decline

A new study shows that people who eat a diet that includes at least half a serving per day of foods high in flavonoids like strawberries, oranges, peppers and apples may have a 20% lower risk of cognitive decline. The research is published in the July 28, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at several types of flavonoids, and found that flavones and anthocyanins may have the most protective effect.

Obesity and Cardiovascular Factors Combine to Cause Cognitive Decline in Latinos

Obesity is a major public health issue among Latinos, and a risk factor for Alzheimer’s disease. But in a new study, researchers at UC San Diego report that cardiometabolic abnormalities, such as hypertension, are more strongly associated with cognitive decline than obesity alone.

UT Southwestern Among Top 25 in Nation in Eight Specialties Ranked By U.S. News ‘Best Hospitals’

UT Southwesternonce again is ranked the No. 1 hospital in Dallas-Fort Worth – the nation’s fourth-largest metro area – among 132 regional hospitals and second in Texas among 566 hospitals for the fifth consecutive year. The recognition comes several months after UT Southwestern completed expansion of its William P. Clements Jr. University Hospital.

UC San Diego Health Ranked #1 by U.S. News & World Report

UC San Diego Health, the region’s only academic health system, is ranked #1 in San Diego and #5 in California, placing it among the nation’s best hospitals, according to the 2021-2022 U.S. News & World Report survey. UC San Diego Health was ranked in the top 50 in 10 specialties.

Rush University Medical Center Again on U.S. News & World Report Honor Roll

Of the more than 3,000 U.S. hospitals evaluated, Rush University Medical Center ranked No. 19 in the nation by U.S. News & World Report, with nine of specialties rated among the country’s very best.

Think About This: Keeping Your Brain Active May Delay Alzheimer’s Dementia 5 Years

Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer’s dementia by up to five years. The research is published in the July 14, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Innovative Gene Therapy ‘Reprograms’ Cells To Reverse Neurological Deficiencies

A new method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities. The study was led by researchers at The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine.

Henry Ford Health System Therapeutic Choir Finds Its Voice Through COVID-19

DETROIT – Henry Ford Health System is using the healing power of singing to help patients with voice disorders that result from various medical conditions such as Parkinson’s disease, stroke and vocal cord paralysis to help improve their voices. Patients in a therapeutic choir called the Motor City Upbeats regain their vocal strength and range and breathing through a series of simple exercises and techniques taught in a welcoming, cheerful environment where just hearing the sound of your voice is music to the ears.

Laboratorios de Mayo Clinic detectan nueva enfermedad autoinmunitaria vinculada al cáncer de testículo

Los Laboratorios de Mayo Clinic pusieron en marcha la primera prueba autoinmunitaria en su clase para el anticuerpo contra la proteína tipo Kelch 11 (KLHL11), que sirve para detectar una enfermedad autoinmunitaria relacionada con el cáncer de testículo. La prueba está disponible a nivel nacional e internacional.

After Stroke, More than One Try to Remove Blood Clots May Be Tied to Worse Outcome

After a stroke, doctors can try to remove clots in blood vessels to keep blood flowing freely to the brain. But even though most of these procedures are successful, less than half of people have a successful recovery from the stroke. A new study published in the June 23, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology, sheds light on why that may be.

Researchers Identify New Gene that May Increase Risk of ALS

Researchers have identified a new gene that may increase a person’s risk of developing ALS, according to a new study published in the June 16, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The gene, called TP73, produces a protein to help regulate the life cycle of a cell. Researchers found that some people with ALS have mutations in this gene and that the mutations may interfere with nerve cell health.

Brain Cell Membranes’ Lipids May Play Big Role in Alzheimer’s Progression

Links between lipid imbalance and disease have been established, in which lipid changes increase the formation of amyloid plaques, a hallmark of Alzheimer’s disease. This imbalance inspired researchers to explore the role of lipids comprising the cellular membranes of brain cells. In Biointerphases, the researchers report on the significant role lipids may play in regulating C99, a protein within the amyloid pathway, and disease progression.

Story Tips from Johns Hopkins Experts on COVID-19

NEWS STORIES IN THIS ISSUE:

-Physician and Musician: Johns Hopkins Doctor Brings Passion for Music to Medicine During Pandemic
-Rapid, At-Home Blood Test Could Confirm COVID-19 Vaccination in Minutes
-What to Expect and Prepare for As You Return to Regular Health Care Appointments
-Study Suggests Sudden Hearing Loss Not Associated with COVID-19 Vaccination
-Vaccination May Not Rid COVID-19 Risk for Those with Rheumatic, Musculoskeletal Diseases

Concussion with Loss of Consciousness May Be Linked to Life with Some Disability

People who have had a concussion where they lost consciousness may be more likely to have some disability or limitations later in life—such as difficulty walking or limitations in the amount or type of work they can do—than people who have never had a concussion, according to a study published in the May 26, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Penn Medicine Launches Region’s First Post-COVID-19 Neurological Care Clinic

As many as one in three COVID-19 survivors experience a mental health or neurological disorder, adding to a growing body of evidence that show COVID-19 can have serious and potentially long-lasting effects on the brain. The Penn Neuro COVID Clinic aims to assess and treat long-haul COVID patients suffering from neurological symptoms.

New Finding Suggests Cognitive Problems Caused by Repeat Mild Head Hits Could Be Treated

A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified. The finding suggests that tailored drug therapy can be designed and developed to reactivate and normalize cognitive function, say neuroscientists at Georgetown University Medical Center.

What Parkinson’s Disease Patients Reveal About How Art is Experienced and Valued

Altered neural functioning, like that experienced in patients with Parkinson’s disease, changes the way art is both perceived and valued. People with neurological motor dysfunction demonstrated decreased experiences of motion in abstract art and enhanced preferences for high-motion art, compared to a healthy control group.

Exercise May Help Slow Cognitive Decline in Some People with Parkinson’s Disease

For people with Parkinson’s disease, problems with thinking and memory skills are among the most common nonmotor symptoms of the disease. A new study shows that exercise may help slow cognitive decline for some people with the disease. The study is published in the March 31, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.

National Neurosurgery Organizations Collaborate to Establish Professionalism Policy for Meetings, Professional Events

Ellen Air, M.D., Ph.D., director of the Neurosurgery Residency Program at Henry Ford Health System and Chair-Elect of the American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Joint Section on Women in Neurosurgery, is co-author of a new Professionalism and Harassment Model Policy created to provide a code of ethical behavior that promotes professional growth and the free exchange of ideas at neurosurgical meetings, educational courses, conferences and other sponsored events.